Browsing by Subject "virus gene"

Amino acid signatures in the HLA class II peptide-binding region associated with protection/susceptibility to the severe West Nile Virus disease

Sarri C.A., Papadopoulos G.E., Papa A., Tsakris A., Pervanidou D., Baka A., Politis C., Billinis C., Hadjichristodoulou C., Mamuris Z. (2018)

The MHC class II region in humans is highly polymorphic. Each MHC molecule is formed by an α and a β chain, produced by different genes, creating an antigen-binding groove. In the groove there are several pockets into which ...

Genetic variability of the HPV16 early genes and LCR. Present and future perspectives

Bletsa G., Zagouri F., Amoutzias G.D., Nikolaidis M., Zografos E., Markoulatos P., Tsakogiannis D. (2021)

Human papillomavirus 16 (HPV16) infection is the aetiologic factor for the development of cervical dysplasia and is regarded as highly carcinogen, because it is implicated in more than 50% of cervical cancer cases, worldwide. ...

Hepatitis B virus and intrahepatic cholangiocarcinoma

Gatselis, N. K.; Tepetes, K.; Loukopoulos, A.; Vasiou, K.; Zafiriou, A.; Gioti, C.; Dalekos, G. N. (2007)

Intrahepatic cholangiocarcinoma (ICC) is a rare type of primary liver cancer that arises from intrahepatic bile ducts. Its etiopathogenesis has been considered to be independent of the presence of chronic viral hepatitis ...

Identification of rearranged sequences of HPV16 DNA in precancerous and cervical cancer cases

Tsakogiannis D., Bletsa M., Kyriakopoulou Z., Dimitriou T.G., Kotsovassilis C., Panotopoulou E., Markoulatos P. (2016)

Integration of HPV16 DNA into the host chromosome is considered to be a crucial step towards genomic instability and cervical cancer development. Aim of the present study was to investigate the presence of HPV16 rearranged ...

Partial 3D gene sequences of Coxsackie viruses reveal interspecies exchanges

Bolanaki, E.; Kottaridi, C.; Markoulatos, P.; Kyriakopoulou, Z.; Margaritis, L.; Katsorchis, T. (2007)

The 3D region of 46 clinical Coxsackievirus strains, primarily belonging to the human enterovirus B species (HEV-B), were analyzed using nucleotide distance matrices and phylogeny software. The conclusions from previously ...

Phylogenetic correlation of Greek and Italian orf virus isolates based on VIR gene

Kottaridi, C.; Nomikou, K.; Teodori, L.; Savini, G.; Lelli, R.; Markoulatos, P.; Mangana, O. (2006)

Thirteen orf virus isolates obtained during the time period between 1995 and 2004 from crusted scab lesions of nine sheep and four goats from different geographical areas of Greece and Italy with suspected contagious ecthyma ...

Polymorphic variability in the exon 19 of the RB1 gene and its flanking intronic sequences in HPV16-associated precancerous lesions in the Greek population

Tsakogiannis D., Moschonas G.D., Daskou M., Stylianidou Z., Kyriakopoulou Z., Kottaridi C., Dimitriou T.G., Gartzonika C., Markoulatos P. (2018)

Purpose. The tumour suppressor protein RB plays a decisive role in negative control of the cell cycle, inhibiting tumour development. The present analysis investigated the prevalence of the nucleotide polymorphism A153104G, ...

WarmStart colorimetric LAMP for the specific and rapid detection of HPV16 and HPV18 DNA

Daskou M., Tsakogiannis D., Dimitriou T.G., Amoutzias G.D., Mossialos D., Kottaridi C., Gartzonika C., Markoulatos P. (2019)

Background and objectives: Persistent infection with High-Risk HPV genotypes is the principal cause for the development of cervical cancer with HPV16 and HPV18 to be the most frequently identified HPV genotypes observed ...