Browsing by Subject "radiation injury"
Now showing items 1-15 of 15
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Addressing the post-irradiation hypothalamic-pituitary endocrine abnormalities of brain tumors in pediatric patients
(2017)Purpose: Hypothalamic-pituitary axis is susceptible to radiotherapy, causing endocrine disorders to childhood cancer survivors. We conducted a systematic review in order to assess the radiation-induced toxicity that leads ... -
Benign intracranial lesions-radiotherapy: An overview of treatment options, indications and therapeutic results
(2020)Background: Radiation Therapy (RT) is an established treatment option for benign intracranial lesions. The aim of this study is to display an update on the role of RT concerning the most frequent benign brain lesions and ... -
Breast radiotherapy and early adverse cardiac effects. The role of serum biomarkers and strain echocardiography
(2019)Breast cancer radiotherapy has a clear benefit for both long-term survival and local recurrence rate. However, there is still much concern about the early radiation-induced heart toxicity. This article aimed to clarify the ... -
Dosimetric and radiobiological evaluation of four radiation techniques in preoperative rectal cancer radiotherapy
(2021)Purpose: To compare tumour dose distribution, conformality, homogeneity, normal tissue avoidance, tumour control probability (TCP) and normal tissue complication probability (NTCP) using 3D conformal radiation therapy ... -
Flash proton radiotherapy spares normal epithelial and mesenchymal tissues while preserving sarcoma response
(2021)In studies of electron and proton radiotherapy, ultrahigh dose rates of FLASH radiotherapy appear to produce fewer toxicities than standard dose rates while maintaining local tumor control. FLASHproton radiotherapy (F-PRT) ... -
High resolution computed tomography findings on the lung of early breast-cancer patients treated by postoperative breast irradiation with a hypofractionated radiotherapy schedule
(2005)BACKGROUND: Hypofractionated breast radiotherapy (RT), although convenient for patients and health care systems, could have a negative impact on normal tissues such as lung. AIM: To evaluate radiation-induced lung toxicity ... -
Honey against radiation-induced oral mucositis in head and neck cancer patients. An umbrella review of systematic reviews and meta-analyses of the literature
(2020)Backround: Oral mucositis (OM) consists of a major side effect of radiotherapy (RT) in head and neck (H-N) cancer patients and natural honey is gaining more and more scientific interest due to its beneficial effects in ... -
How can we effectively address the paraneoplastic dermatomyositis: Diagnosis, risk factors and treatment options
(2017)Purpose: Dermatomyositis (DM) represents an auto-immune inflammatory myopathy. In this review, we analyzed the incidence of DM as a clinical manifestation highlighting the peculiar clinical and treatment characteristics ... -
Intraoperative radiation therapy (IORT) in head and neck cancer: A systematic review
(2016)Background: Multimodality therapy constitutes the standard treatment of advanced and recurrent head and neck cancer. Since locoregional recurrence comprises a major obstacle in attaining cure, the role of intraoperative ... -
Is locally advanced head-neck cancer one more candidate for accelerated hypofractionation?
(2021)Background/Aim: Hypofractionated accelerated radiotherapy (HypoAR) is widely applied for the treatment of early laryngeal cancer. Its role in locally advanced head-neck cancer (LA-HNC) is unexplored. Patients and Methods: ... -
Late results of a randomized trial on the role of mild hypofractionated radiotherapy for the treatment of localized prostate cancer
(2020)Background: Prostate cancer is considered to be highly sensitive to changes in radiation therapy dose per fraction, specifically to hypofractionation. An increase in the fractionation dose could cause a higher increase to ... -
Molecular determinants of radiosensitivity in normal and tumor tissue: A bioinformatic approach
(2017)Although radiation therapy is a treatment of choice for cancer, a high percentage of patients develop adverse effects in normal tissue following radiotherapy, mainly, due to genetic factors. Notably, although it is established ... -
A Retrospective Analysis of Toxicity and Efficacy for 2 Hypofractionated Irradiation Schedules Versus a Conventional One for Post-Mastectomy Adjuvant Radiotherapy in Breast Cancer
(2016)Introduction: The aim of this analysis was a retrospective evaluation of the efficacy and toxicity of 2 hypofractionated irradiation schedules compared to conventional therapy in post-mastectomy patients. Methods: 3 ... -
Stage-II thymoma and emergency coronary artery bypass. To irradiate or not to irradiate to avoid radiation induced vascular injury? Case report and literature review
(2017)Purpose: The purpose of this study was to present the controversial role of adjuvant radiotherapy to a 72-year-old male patient with Masaoka stage II thymoma and coronary artery bypass and to review the relevant literature. ... -
Vaginal dilator use to promote sexual wellbeing after radiotherapy in gynecological cancer survivors
(2022)AbstractThis study investigated the efficacy of a vaginal dilator (VD) for the treatment of radiation-induced vaginal stenosis (VS) and the effect of a VD on sexual quality of life.Fifty three patients with endometrial or ...