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Browsing by Subject "protein deficiency"

Now showing items 1-3 of 3

    • Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection 

      Xu, H. C.; Huang, J.; Khairnar, V.; Duhan, V.; Pandyra, A. A.; Grusdat, M.; Shinde, P.; McIlwain, D. R.; Maney, S. K.; Gommerman, J.; Löhning, M.; Ohashi, P. S.; Mak, T. W.; Pieper, K.; Sic, H.; Speletas, M.; Eibel, H.; Ware, C. F.; Tumanov, A. V.; Kruglov, A. A.; Nedospasov, S. A.; Häusinger, D.; Recher, M.; Lang, K. S.; Lang, P. A. (2015)
      The B cell-activating factor (BAFF) is critical for B cell development and humoral immunity in mice and humans. While the role of BAFF in B cells has been widely described, its role in innate immunity remains unknown. Using ...

    • Genetic determinants of C1 inhibitor deficiency angioedema age of onset 

      Gianni P., Loules G., Zamanakou M., Kompoti M., Csuka D., Psarros F., Magerl M., Moldovan D., Maurer M., Speletas M.G., Farkas H., Germenis A.E. (2017)
      Background: In view of the large heterogeneity in the clinical presentation of hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE), great efforts are being made towards detecting measurable biological ...

    • MBL deficiency-causing B allele (rs1800450) as a risk factor for severe COVID-19 

      Speletas M., Dadouli K., Syrakouli A., Gatselis N., Germanidis G., Mouchtouri V.A., Koulas I., Samakidou A., Nikolaidou A., Stefos A., Mimtsoudis I., Hatzianastasiou S., Koureas M., Anagnostopoulos L., Tseroni M., Tsinti G., Metallidis S., Dalekos G., Hadjichristodoulou C. (2021)
      The COVID-19 pandemic represents one of the greatest challenges in modern medicine. The disease is characterized by a variable clinical phenotype, ranging from asymptomatic carriage to severe and/or critical disease, which ...