Browsing by Subject "dementia"

Adherence to Mediterranean Diet and Frailty

Ntanasi E., Yannakoulia M., Kosmidis M.-H., Anastasiou C.A., Dardiotis E., Hadjigeorgiou G., Sakka P., Scarmeas N. (2018)

Objective: Το investigate associations between adherence to the Mediterranean diet and frailty in a Greek population of older adults. Design: Cross-sectional study. Setting: Data were drawn from the Hellenic longitudinal ...

Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study

Lipnicki D.M., Crawford J.D., Dutta R., Thalamuthu A., Kochan N.A., Andrews G., Lima-Costa M.F., Castro-Costa E., Brayne C., Matthews F.E., Stephan B.C.M., Lipton R.B., Katz M.J., Ritchie K., Scali J., Ancelin M.-L., Scarmeas N., Yannakoulia M., Dardiotis E., Lam L.C.W., Wong C.H.Y., Fung A.W.T., Guaita A., Vaccaro R., Davin A., Kim K.W., Han J.W., Kim T.H., Anstey K.J., Cherbuin N., Butterworth P., Scazufca M., Kumagai S., Chen S., Narazaki K., Ng T.P., Gao Q., Reppermund S., Brodaty H., Lobo A., Lopez-Anton R., Santabárbara J., Sachdev P.S., Cohort Studies of Memory in an International Consortium (COSMIC) (2017)

Background: The prevalence of dementia varies around the world, potentially contributed to by international differences in rates of age-related cognitive decline. Our primary goal was to investigate how rates of age-related ...

Alzheimer’s disease in patients with obstructive sleep apnea syndrome

Siachpazidou D.I., Stavrou V.T., Astara K., Pastaka C., Gogou E., Hatzoglou C., Economou N.-T., Gourgoulianis K.I. (2020)

Background: Obstructive sleep apnea syndrome (OSAS) is a disorder with high prevalence among adults and is an independent risk factor for various diseases, especially those affecting the central nervous system (CNS). ...

Anosognosia in Dementia: Evaluation of Perfusion Correlates Using 99mTc-HMPAO SPECT and Automated Brodmann Areas Analysis

Valotassiou V., Sifakis N., Tzavara C., Lykou E., Tsinia N., Kamtsadeli V., Sali D., Angelidis G., Psimadas D., Theodorou E., Tsougos I., Papageorgiou S.G., Georgoulias P., Papatriantafyllou J. (2022)

(1) Background: Considerable inconsistency exists regarding the neural substrates of anosognosia in dementia in previous neuroimaging studies. The purpose of this study was the evaluation of anosognosia perfusion correlates ...

Antihypertensive Medication Class and the Risk of Dementia and Cognitive Decline in Older Adults: A Secondary Analysis of the Prospective HELIAD Cohort

Liampas I., Hatzimanolis A., Siokas V., Yannakoulia M., Kosmidis M.H., Sakka P., Hadjigeorgiou G.M., Scarmeas N., Dardiotis E. (2022)

Background: It is unclear whether the main antihypertensive medication classes (diuretics, calcium channel blockers, beta-blockers, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers (ARBs)) are ...

Apolipoprotein ϵ4 allele is associated with frailty syndrome: Results from the hellenic longitudinal investigation of ageing and diet study

Mourtzi N., Ntanasi E., Yannakoulia M., Kosmidis M., Anastasiou C., Dardiotis E., Hadjigeorgiou G., Sakka P., Scarmeas N. (2019)

Apolipoprotein (APOE) ϵ4 allele has been associated with a number of age-related diseases but previous studies failed to identify any link with Frailty syndrome. The aim of the present study is to investigate the association ...

Assessing functional status using the IADL-extended scale: Results from the HELIAD study

Kalligerou F., Fieo R., Paraskevas G.P., Zalonis I., Kosmidis M.H., Yannakoulia M., Ntanasi E., Dardiotis E., Hadjigeorgiou G., Sakka P., Scarmeas N. (2020)

Objectives: Instrumental activities of daily living (IADL) have been operationalized as exhibiting a greater level of complexity than basic ADL. In the same way, incorporating more advanced ADLs may increase the sensitivity ...

Association between 9p21–23 Locus and Frailty in a Community-Dwelling Greek Population: Results from the Hellenic Longitudinal Investigation of Ageing and Diet

Mourtzi N., Hatzimanolis A., Xiromerisiou G., Ntanasi E., Georgakis M.K., Ramirez A., Heilmann-Heimbach S., Grenier-Boley B., Lambert J.C., Yannakoulia M., Kosmidis M., Dardiotis E., Hadjigeorgiou G., Sakka P., Scarmeas N. (2022)

Background: Frailty is a complex geriatric syndrome arising from a combination of genetic and environmental factors and is associated with adverse health outcomes and mortality. A recent study reported an association between ...

Association between Motor Signs and Cognitive Performance in Cognitively Unimpaired Older Adults: A Cross-Sectional Study Using the NACC Database

Siokas V., Liampas I., Lyketsos C.G., Dardiotis E. (2022)

Aiming to examine whether specific motor signs are associated with worse performance in specific cognitive domains among cognitively unimpaired (CU) individuals, we performed a cross-sectional analysis of data from the ...

Association Between Sleep Disturbances and Frailty: Evidence From a Population-Based Study

Balomenos V., Ntanasi E., Anastasiou C.A., Charisis S., Velonakis G., Karavasilis E., Tsapanou A., Yannakoulia M., Kosmidis M.H., Dardiotis E., Hadjigeorgiou G., Sakka P., Scarmeas N. (2021)

Objective: To explore the association between both self-reported quality and quantity sleep characteristics and frailty status in a large non–sex-specific population of older individuals in Greece. Design: Cross-sectional ...

The Association of Sedentary Behaviour and Cognitive Function in People Without Dementia: A Coordinated Analysis Across Five Cohort Studies from COSMIC

Maasakkers C.M., Claassen J.A.H.R., Gardiner P.A., Olde Rikkert M.G.M., Lipnicki D.M., Scarmeas N., Dardiotis E., Yannakoulia M., Anstey K.J., Cherbuin N., Haan M.N., Kumagai S., Narazaki K., Chen T., Ng T.P., Gao Q., Nyunt M.S.Z., Crawford J.D., Kochan N.A., Makkar S.R., Sachdev P.S., Thijssen D.H.J., Melis R.J.F., COSMIC Collaborators (2020)

Background: Besides physical activity as a target for dementia prevention, sedentary behaviour is hypothesized to be a potential target in its own right. The rising number of persons with dementia and lack of any effective ...

Association of the Polygenic Risk Score With the Probability of Prodromal Parkinson’s Disease in Older Adults

Maraki M.I., Hatzimanolis A., Mourtzi N., Stefanis L., Yannakoulia M., Kosmidis M.H., Dardiotis E., Hadjigeorgiou G.M., Sakka P., Ramirez A., Grenier-Boley B., Lambert J.-C., Heilmann-Heimbach S., Stamelou M., Scarmeas N., Xiromerisiou G. (2021)

Several studies have investigated the association of the Parkinson’s disease (PD) polygenic risk score (PRS) with several aspects of well-established PD. We sought to evaluate the association of PRS with the prodromal stage ...

Associations between sleep and obesity indices in older adults: results from the HELIAD study

Mamalaki E., Tsapanou A., Anastasiou C.A., Kosmidis M.H., Dardiotis E., Hadjigeorgiou G.M., Sakka P., Scarmeas N., Yannakoulia M. (2019)

Background: Short sleep duration and low sleep quality are negatively associated with obesity in young adults, but in older people the results are inconsistent. Aims: The aim of the present study was to examine the ...

Atrial fibrillation and cognitive decline: it takes more than an irregular heart beat, to beat the brain

Sagris D., Lip G.Y.H. (2021)

[No abstract available]

Atrial Fibrillation and Dementia: A Report From the AF-SCREEN International Collaboration

Rivard L., Friberg L., Conen D., Healey J.S., Berge T., Boriani G., Brandes A., Calkins H., Camm A.J., Yee Chen L., Lluis Clua Espuny J., Collins R., Connolly S., Dagres N., Elkind M.S.V., Engdahl J., Field T.S., Gersh B.J., Glotzer T.V., Hankey G.J., Harbison J.A., Georg Haeusler K., Hills M.T., Johnson L.S.B., Joung B., Khairy P., Kirchhof P., Krieger D., Lip G.Y.H., Løchen M.-L., Madhavan M., Mairesse G.H., Montaner J., Ntaios G., Quinn T.J., Rienstra M., Rosenqvist M., Sandhu R.K., Smyth B., Schnabel R.B., Stavrakis S., Themistoclakis S., Van Gelder I.C., Wang J.-G., Freedman B. (2022)

Growing evidence suggests a consistent association between atrial fibrillation (AF) and cognitive impairment and dementia that is independent of clinical stroke. This report from the AF-SCREEN International Collaboration ...

Atrial Fibrillation Is Associated with Cognitive Impairment, All-Cause Dementia, Vascular Dementia, and Alzheimer’s Disease: a Systematic Review and Meta-Analysis

Papanastasiou C.A., Theochari C.A., Zareifopoulos N., Arfaras-Melainis A., Giannakoulas G., Karamitsos T.D., Palaiodimos L., Ntaios G., Avgerinos K.I., Kapogiannis D., Kokkinidis D.G. (2021)

Background: Atrial fibrillation (AF) is a risk factor for cognitive impairment and dementia in patients with stroke history. However, the association between AF and cognitive impairment in broader populations is less clear. ...

Can a Virtual Reality Cognitive Training Application Fulfill a Dual Role? Using the Virtual Supermarket Cognitive Training Application as a Screening Tool for Mild Cognitive Impairment

Zygouris, S.; Giakoumis, D.; Votis, K.; Doumpoulakis, S.; Ntovas, K.; Segkouli, S.; Karagiannidis, C.; Tzovaras, D.; Tsolaki, M. (2015)

Background: Recent research advocates the potential of virtual reality (VR) applications in assessing cognitive functions highlighting the possibility of using a VR application for mild cognitive impairment (MCI) screening. ...

Care of Patients with Alzheimer’s Disease

Athanasiadou E., Tsaloglidou A., Koukourikos K., Papathanasiou I.V., Iliadis C.H., Frantzana A., Fradelos E., Kourkouta L. (2021)

Introduction: Alzheimer’s disease is one of the irreversible dementias and leads to death. About 10% of people over 60 years and 20% of people over 80 will have Alzheimer’s sometime in their lives. In the case of Alzheimer’s ...

Cognitive impairment in heart failure

Dardiotis, E.; Giamouzis, G.; Mastrogiannis, D.; Vogiatzi, C.; Skoularigis, J.; Triposkiadis, F.; Hadjigeorgiou, G. M. (2012)

Cognitive impairment (CI) is increasingly recognized as a common adverse consequence of heart failure (HF). Although the exact mechanisms remain unclear, microembolism, chronic or intermittent cerebral hypoperfusion, and/or ...

Construction of joint confidence regions for the optimal true class fractions of Receiver Operating Characteristic (ROC) surfaces and manifolds

Bantis L.E., Nakas C.T., Reiser B., Myall D., Dalrymple-Alford J.C. (2017)

The three-class approach is used for progressive disorders when clinicians and researchers want to diagnose or classify subjects as members of one of three ordered categories based on a continuous diagnostic marker. The ...