Browsing by Subject "clinical study"
Now showing items 1-16 of 16
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A 13- to 16-year clinical and radiological outcome study of the genesis II cruciate retaining total knee arthroplasty with an oxidised zirconium femoral component
(2019)Purpose: The Genesis II Total Knee Arthroplasty with an oxidized zirconium (OxiniumTM) femoral component (Smith & Nephew, Memphis, TN, USA) was introduced in an attempt to reduce polyethylene wear and osteolysis. Methods: ... -
Adrenocorticotropic hormone: an effective “natural” biologic therapy for acute gout?
(2020)Treatment of acute gout consists of non-steroidal anti-inflammatory drugs (NSAIDs), colchicine and steroids. However, the typical patient with gout has multiple comorbidities such as cardiovascular disease, hypertension, ... -
Angiotensin receptor-neprilysin inhibition in patients with acute decompensated heart failure: an expert consensus position paper
(2022)The short-term mortality and rehospitalization rates after admission for acute heart failure (AHF) remain high, despite the high level of adherence to contemporary practice guidelines. Observational data from non-randomized ... -
Association of IL-10 gene promoter polymorphisms with food allergy susceptibility and serum IL-10 level in a pediatric Caucasian population
(2021)Background: Interleukin 10 has been shown to play a critical role in the regulation of the immune responses in allergic diseases. Aim: To investigate if genetic polymorphisms in the promoter region of the IL-10 gene are ... -
A critical review of exercise as a treatment for clinically depressed adults: Time to get pragmatic
(2017)Objective Although considerable evidence supports the efficacy of exercise as an antidepressant treatment, critical reviews informing routine practice and future research directions are scarce. Methods We critically reviewed ... -
Exercise works for depression: Bridging the implementation gap and making exercise a core component of treatment
(2017)[No abstract available] -
Explainable machine learning for knee osteoarthritis diagnosis based on a novel fuzzy feature selection methodology
(2022)Knee Osteoarthritis (ΚΟΑ) is a degenerative joint disease of the knee that results from the progressive loss of cartilage. Due to KOA’s multifactorial nature and the poor understanding of its pathophysiology, there is a ... -
Fabry disease due to D313Y and novel GLA mutations
(2017)Objectives Our aim is to report four novel α-gal A gene (GLA) mutations resulting in Fabry disease (FD) and provide evidence of pathogenicity of the D313Y mutation regarding which contradictory data have been presented in ... -
Geographical variation in therapy for bloodstream infections due to multidrug-resistant Enterobacteriaceae: a post-hoc analysis of the INCREMENT study
(2017)We describe regional differences in therapy for bloodstream infection (BSI) caused by extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) or carbapenemase-producing Enterobacteriaceae (CPE). Patients (n = ... -
Interrupted versus uninterrupted anticoagulation therapy for catheter ablation in adults with arrhythmias
(2021)Background: The management of anticoagulation therapy around the time of catheter ablation (CA) procedure for adults with arrhythmia is critical and yet is variable in clinical practice. The ideal approach for safe and ... -
Medical-grade honey outperforms conventional treatments for healing cold sores—A clinical study
(2021)Cold sores are nasolabial blisters caused by herpes simplex virus (HSV) infections. Novel therapies demonstrating simultaneously antiviral activity and improved wound healing are war-ranted. The aim of this study was to ... -
Monoclonal Antibody Biosimilars in Oncology: Critical Appraisal of Available Data on Switching
(2018)Purpose: With the introduction of biosimilars of anticancer monoclonal antibodies (mAbs) in oncology, physicians are potentially confronted with the question whether it is clinically adequate to switch patients who are ... -
Prevalence and risk factors of overweight and obesity among adolescents and their parents in central Greece (FETA Project)
(2015)The increasing obesity trend in adolescence is a public health concern. The initial phase of Feeding Exercise Trial in Adolescents (FETA) aimed in investigating the prevalence of overweight and obesity in adolescents and ... -
Repetitive use of levosimendan in advanced heart failure: need for stronger evidence in a field in dire need of a useful therapy
(2017)Patients in the latest stages of heart failure are severely compromised, with poor quality of life and frequent hospitalizations. Heart transplantation and left ventricular assist device implantation are viable options ... -
The role of nitric oxide synthase inhibitors in schizophrenia
(2016)Close to 1% of the world population suffer from schizophrenia. Current medications for this chronic mental disorder have greatly improved treatment over the last half century or more, but, the newer atypical antipsychotics ... -
The second greek–israeli symposium on autoimmunity and rheumatology: Success through synergy
(2019)[No abstract available]