Browsing by Subject "biological activity"

Anthocyanin-rich extracts from purple and red potatoes as natural colourants: Bioactive properties, application in a soft drink formulation and sensory analysis

Sampaio S.L., Lonchamp J., Dias M.I., Liddle C., Petropoulos S.A., Glamočlija J., Alexopoulos A., Santos-Buelga C., Ferreira I.C.F.R., Barros L. (2021)

Aqueous extracts from seven coloured potato varieties (three red-fleshed, three-purple fleshed, and one marble-fleshed) were studied for their anthocyanin content, in vitro biological activities, colouring properties and ...

Assessment of antioxidant and antimutagenic properties of red and white wine extracts in vitro

Tekos F., Makri S., Skaperda Z.-V., Patouna A., Terizi K., Kyriazis I.D., Kotseridis Y., Mikropoulou E.V., Papaefstathiou G., Halabalaki M., Demetrios K. (2021)

Wine is an alcoholic beverage of complex composition obtained through the fermentation of grape must. The consumption of wine has already been associated with a multitude of beneficial effects due to its high polyphenolic ...

Bioactive properties of Sanguisorba minor L. cultivated in central Greece under different fertilization regimes

Finimundy T.C., Karkanis A., Fernandes Â., Petropoulos S.A., Calhelha R., Petrović J., Soković M., Rosa E., Barros L., Ferreira I.C.F.R. (2020)

In this study, the chemical characterization and bioactive properties of S. minor cultivated under different fertilization rates (control, half rate and full rate) were evaluated. Twenty-two phenolic compounds were identified, ...

Biological properties of bee bread collected from apiaries located across Greece

Didaras N.A., Kafantaris I., Dimitriou T.G., Mitsagga C., Karatasou K., Giavasis I., Stagos D., Amoutzias G.D., Hatjina F., Mossialos D. (2021)

Bee bread is the only fermented product of the beehive. It constitutes the main source of proteins, lipids, vitamins, and macro-and microelements in honeybee nutrition and it exerts antioxidant and antimicrobial properties, ...

Chemical composition and bioactive compounds of garlic (Allium sativum L.) as affected by pre- and post-harvest conditions: A review

Martins N., Petropoulos S., Ferreira I.C.F.R. (2016)

Garlic (Allium sativum L.) is considered one of the twenty most important vegetables, with various uses throughout the world, either as a raw vegetable for culinary purposes, or as an ingredient of traditional and modern ...

Chemical composition and biological activity of cardoon (Cynara cardunculus L. var. altilis) seeds harvested at different maturity stages

Mandim F., Petropoulos S.A., Pinela J., Dias M.I., Giannoulis K.D., Kostić M., Soković M., Queijo B., Santos-Buelga C., Ferreira I.C.F.R., Barros L. (2022)

Cardoon seeds collected in Greece at four different maturity stages (samples S1 to S4) were analysed in terms of chemical composition and in vitro bioactivities. The content of phenolic compounds (six compounds in total) ...

Chronic obstructive pulmonary disease as a main factor of premature aging

Karametos I., Tsiboli P., Togousidis I., Hatzoglou C., Giamouzis G., Gourgoulianis K.I. (2019)

(1) Background: Chronic obstructive pulmonary disease (COPD) is defined as an inflammatory disorder that presents an increasingly prevalent health problem. Accelerated aging has been examined as a pathologic mechanism of ...

IFNs-signaling effects on lung cancer: an up-to-date pathways-specific review

Galani V., Kastamoulas M., Varouktsi A., Lampri E., Mitselou A., Arvanitis D.L. (2017)

IFNs have found important applications in clinical medicine, including the treatment of lung malignancies. The biological effect of the IFN-receptor signaling is regulated essentially by three factors: the expression profile ...

In Vivo Estimation of the Biological Effects of Endocrine Disruptors in Rabbits after Combined and Long-Term Exposure: Study Protocol

Karzi V., Tzatzarakis M.N., Alegakis A., Vakonaki E., Fragkiadoulaki I., Kaloudis K., Chalkiadaki C., Apalaki P., Panagiotopoulou M., Kalliantasi A., Kouretas D., Docea A.O., Calina D., Tsatsakis A. (2022)

Recently, an increasing number of chemical compounds are being characterized as endocrine disruptors since they have been proven to interact with the endocrine system, which plays a crucial role in the maintenance of ...

Inflammaging and Skeletal Muscle: Can Protein Intake Make a Difference?

Draganidis D., Karagounis L.G., Athanailidis I., Chatzinikolaou A., Jamurtas A.Z., Fatouros I.G. (2016)

Inflammaging is the chronic low-grade inflammatory state present in the elderly, characterized by increased systemic concentrations of proinflammatory cytokines. It has been shown that inflammaging increases the risk of ...

An integrated approach for assessing the in vitro and in vivo redox-related effects of nanomaterials

Vardakas P., Skaperda Z., Tekos F., Trompeta A.-F., Tsatsakis A., Charitidis C.A., Kouretas D. (2021)

Over the last few decades, nanotechnology has risen to the forefront of both the research and industrial interest, resulting in the manufacture and utilization of various nanomaterials, as well as in their integration into ...

Multicomponent reaction of aldehydes, amines and oxalacetate analogues leading to biologically attractive pyrrole derivatives

Manta S., Kollatos N., Mitsos C., Chatzieffraimidi G.-A., Papanastasiou I., Gallos J.K., Komiotis D. (2020)

Pyrrole is a very important pharmacophoric moiety. It has been widely incorporated into the skeleton of antitumor, anti-inflammatory, antibacterial, antioxidant and antifungal active substances. Access to this key heterocycle ...