Browsing by Subject "Sulfolobus"
Now showing items 1-2 of 2
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A freestanding proofreading domain is required for protein synthesis quality control in Archaea
(2004)Threonyl-tRNA synthetase (ThrRS) participates in protein synthesis quality control by selectively editing the misacylated species Ser-tRNAThr. In bacteria and eukaryotes the editing function of ThrRS resides in a highly ... -
A unique hydrophobic cluster near the active site contributes to differences in borrelidin inhibition, among threonyl-tRNA synthetases
(2005)Borrelidin, a compound with anti-microbial and anti-angiogenic properties, is a known inhibitor of bacterial and eukaryal threonyl-tRNA synthetase (ThrRS). The inhibition mechanism of borrelidin is not well understood. ...