Browsing by Subject "SUPEROVULATED WOMEN"

Attenuating activity of the ovary on LH response to GnRH during the follicular phase of the cycle

Dimitraki, M.; Messini, C. I.; Dafopoulos, K.; Gioka, T.; Koutlaki, N.; Garas, A.; Georgoulias, P.; Messinis, I. E. (2014)

Objective Oestradiol sensitizes the pituitary to GnRH, while gonadotrophin surge attenuating factor (GnSAF) may oppose this action. Using the LH response to GnRH during treatment with FSH as an in vivo bioassay for GnSAF, ...

Changes in pituitary sensitivity to GnRH in estrogen-treated post-menopausal women: evidence that gonadotrophin surge attenuating factor plays a physiological role

Dafopoulos, K.; Kotsovassilis, C. G.; Milingos, S.; Kallitsaris, A.; Galazios, G.; Zintzaras, E.; Sotiros, P.; Messinis, I. E. (2004)

BACKGROUND: The purpose of this study was to investigate changes in pituitary response to GnRH in post-menopausal women during substitution treatment with exogenous estrogen and progesterone. METHODS: Seven healthy ...

Evidence that termination of the estradiol-induced luteinizing hormone surge in women is regulated by ovarian factors

Dafopoulos, K.; Mademtzis, I.; Vanakara, P.; Kallitsaris, A.; Stamatiou, G.; Kotsovassilis, C.; Messinis, I. E. (2006)

Background: The endogenous LH surge is the result of the estrogen-positive feedback effect. However, the factors that are responsible for the termination of LH surge are not known. Objective: The objective of the study was ...

From menarche to regular menstruation - Endocrinological background

Messinis, I. E. (2006)

Marked changes in hormone secretion occur from childhood to adulthood. Prior to puberty gonadotropin-releasing hormone (GnRH) secretion is markedly suppressed. At the onset of puberty, the hypothalamic gonadostat is ...

Luteinizing hormone response to gonadotrophin-releasing hormone in normal women undergoing ovulation induction with urinary or recombinant follicle stimulating hormone

Messinis, I. E.; Milingos, S.; Zikopoulos, K.; Hasiotis, G.; Seferiadis, K.; Lolis, D. (1998)

Oestradiol enhances pituitary sensitivity to gonadotrophin-releasing hormone (GnRH) in normal women, while in women undergoing ovulation induction the putative factor gonadotrophin surge attenuating factor (GnSAF) attenuates ...

The recombinant subdomain IIIB of human serum albumin displays activity of gonadotrophin surge-attenuating factor

Tavoulari, S.; Frillingos, S.; Karatza, P.; Messinis, I. E.; Seferiadis, K. (2004)

BACKGROUND: Gonadotrophin surge-attenuating factor (GnSAF) is an as yet unidentified ovarian factor that acts on the pituitary to attenuate the pre-ovulatory LH surge. In a previous study, GnSAF bioactivity was proposed ...