Browsing by Subject "Osteoporosis"

Bovine colostrum supplementation improves bone metabolism in an osteoporosis-induced animal model

Kydonaki E.K., Freitas L., Fonseca B.M., Reguengo H., Simón C.R., Bastos A.R., Fernandes E.M., Canadas R.F., Oliveira J.M., Correlo V.M., Reis R.L., Vliora M., Gkiata P., Koutedakis Y., Ntina G., Pinto R., Carrillo A.E., Marques F., Amorim T. (2021)

Osteoporosis is characterized by bone loss. The present study aims to investigate the effects of bovine colostrum (BC) on bone metabolism using ovariectomized (OVX) and orchidec-tomized (ORX) rat models. Twenty-seven-week-old ...

Comparable or higher prevalence of comorbidities in antiphospholipid syndrome vs rheumatoid arthritis: A multicenter, case-control study

Panopoulos S., Thomas K., Georgiopoulos G., Boumpas D., Katsiari C., Bertsias G., Drosos A.A., Boki K., Dimitroulas T., Garyfallos A., Papagoras C., Katsimbri P., Tziortziotis A., Adamichou C., Kaltsonoudis E., Argyriou E., Vosvotekas G., Sfikakis P.P., Vassilopoulos D., Tektonidou M.G. (2021)

Objectives: Evidence on comorbidity prevalence in antiphospholipid syndrome (APS) and its difference from high comorbidity burden rheumatic diseases is limited. Herein, we compare multiple comorbidities between APS and RA. ...

Cortical and trabecular bone analysis of professional dancers using 3D-DXA: a case–control study

Freitas L., Amorim T., Humbert L., Fonollá R., Flouris A.D., Metsios G.S., Jamurtas A.Z., Koutedakis Y. (2019)

Given the lack of relevant data, the aim of this study was to examine femur cortical and trabecular bone in female and male professional ballet dancers. 40 professional ballet dancers and 40 sex- and age-matched non-exercising ...

Do Calcium Supplements Predispose to Urolithiasis?

Kozyrakis D., Paridis D., Karatzas A., Soukias G., Dailiana Z. (2017)

Purpose of Review: The purpose of this study was to investigate the role of calcium supplements, with or without vitamin D, in urinary stone formation in healthy population and in osteoporotic patients as well. Moreover, ...

Genetic variation in Wnt/β-catenin and ER signalling pathways in female and male elite dancers and its associations with low bone mineral density: a cross-section and longitudinal study

Amorim T., Durães C., Machado J.C., Metsios G.S., Wyon M., Maia J., Flouris A.D., Marques F., Nogueira L., Adubeiro N., Koutedakis Y. (2018)

Summary: The association of genetic polymorphisms with low bone mineral density in elite athletes have not been considered previously. The present study found that bone mass phenotypes in elite and pre-elite dancers are ...

MR imaging findings in early osteoarthritis of the knee

Karachalios, T.; Zibis, A.; Papanagiotou, P.; Karantanas, A. H.; Malizos, K. N.; Roidis, N. (2004)

Purpose: To carry out a modern diagnostic survey among patients with a clinical and radiological diagnosis of early osteoarthritis of the knee. Materials and methods:A magnetic resonance imaging survey was performed on 70 ...

A neuroprotective bovine colostrum attenuates apoptosis in dexamethasone‐treated mc3t3‐e1 osteoblastic cells

Martin‐aragon S., Bermejo‐bescós P., Benedí J., Raposo C., Marques F., Kydonaki E.K., Gkiata P., Koutedakis Y., Ntina G., Carrillo A.E., Amorim T. (2021)

Glucocorticoid‐induced osteoporosis (GIO) is one of the most common secondary forms of osteoporosis. GIO is partially due to the apoptosis of osteoblasts and osteocytes. In addition, high doses of dexamethasone (DEX), a ...

Novel Sequence Variations in the CER1 Gene Are Strongly Associated with Low Bone Mineral Density and Risk of Osteoporotic Fracture in Postmenopausal Women

Koromila, T.; Dailiana, Z.; Samara, S.; Chassanidis, C.; Tzavara, C.; Patrinos, G. P.; Aleporou-Marinou, V.; Kollia, P. (2012)

Osteoporosis is a common skeletal disease characterized by a combination of low bone mass and increased fragility. In this case-control study, we investigated the possible association of two novel candidate genes, CER1 and ...

Nutraceutical Supplementation Based on Colostrum as Osteoporosis Treatment: A Pilot Study

Styliani Ziaka; Tânia Amorim; Maria Vliora; Paraskevi Gkiata; Konstantinos Mantzios; Georgia Ntina; Eirini K. Kydonaki; Vasileios Gkizlis; Yiannis Koutedakis (2021)

Introduction: Naturally based treatments for osteoporosis are currently limited. The purpose of this investigation was to ascertain whether bovine colostrum supplementation can improve bone health in humans. Methods: In ...

Pharmacological and Non-Pharmacological Agents versus Bovine Colostrum Supplementation for the Management of Bone Health Using an Osteoporosis-Induced Rat Model

Kydonaki E.K., Freitas L., Reguengo H., Simón C.R., Bastos A.R., Fernandes E.M., Canadas R.F., Oliveira J.M., Correlo V.M., Reis R.L., Vliora M., Gkiata P., Koutedakis Y., Ntina G., Pinto R., Carrillo A.E., Marques F., Amorim T. (2022)

Osteoporosis is defined by loss of bone mass and deteriorated bone microarchitecture. The present study compared the effects of available pharmacological and non-pharmacological agents for osteoporosis [alendronate (ALE) ...

Prevalence of comorbidities in systemic sclerosis versus rheumatoid arthritis: a comparative, multicenter, matched-cohort study

Panopoulos S., Tektonidou M., Drosos A.A., Liossis S.-N., Dimitroulas T., Garyfallos A., Sakkas L., Boumpas D., Voulgari P.V., Daoussis D., Thomas K., Georgiopoulos G., Vosvotekas G., Vassilopoulos D., Sfikakis P.P. (2018)

BACKGROUND: Comorbidities are common in chronic systemic connective tissue diseases and are associated with adverse outcomes, increased morbidity and mortality. Although the prevalence of comorbidities has been well-studied ...

Searching for the ‘winner’ hip fracture patient: the effect of modifiable and non-modifiable factors on clinical outcomes following hip fracture surgery

Makridis K.G., Badras L.S., Badras S.L., Karachalios T.S. (2021)

Background: Various factors, other than the quality of surgery, may influence clinical outcomes of hip fracture patients. We aimed to evaluate the relative impact of several factors on functional outcome, quality of life, ...