Browsing by Subject "Migfilin"

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Experimental evidence of Migfilin as a new therapeutic target of hepatocellular carcinoma metastasis

Gkretsi, V.; Bogdanos, D. P. (2015)

Migfilin is a novel cell-matrix adhesion protein known to interact with Vasodilator Stimulated Phosphoprotein (VASP) and be localized both at cell-matrix and cell-cell adhesions. To date there is nothing known about its ...
Migfilin's elimination from osteoarthritic chondrocytes further promotes the osteoarthritic phenotype via beta-catenin upregulation

Gkretsi, V.; Papanikolaou, V.; Dubos, S.; Papathanasiou, I.; Giotopoulou, N.; Valiakou, V.; Wu, C. Y.; Malizos, K. N.; Tsezou, A. (2013)

Osteoarthritis (OA) is a debilitating disease of the joints characterized by cartilage degradation but to date there is no available pharmacological treatment to inhibit disease progression neither is there any available ...
Mitogen-inducible gene-2 (MIG2) and migfilin expression is reduced in samples of human breast cancer

Gkretsi, V.; Papanikolaou, V.; Zacharia, L. C.; Athanassiou, E.; Wu, C.; Tsezou, A. (2013)

Background: Cell adhesion proteins that connect each cell to neighboring cells and the extracellular matrix play a fundamental role in metastasis. Mitogen-inducible gene-2 (MIG2), is a cell-matrix adhesion protein, which ...