Browsing by Subject "Bentham Science Publishers B.V."
Now showing items 1-20 of 29
-
Affinity crystallography reveals the bioactive compounds of industrial juicing byproducts of Punica granatum for glycogen phosphorylase
(2018)Background: Glycogen phosphorylase (GP) is a pharmaceutical target for the discovery of new antihyperglycaemic agents. Punica granatum is a well-known plant for its potent antioxidant and antimicrobial activities but so ... -
Analytical side-to-side related anastomotic strategies and artery patching
(2015)Suture line stress concentration and intimal hyperplasia are related to the long-term complications of end-toside and side-to-side anastomosis. Several factors, such as hemodynamic effects, biological activities and the ... -
Application of efficient nanoparticles for early diagnosis and treatment of cancer
(2015)Cancer is considered as a prevalent cause of human deaths and undoubtedly, is the most complex disease with multiple cellular physiological systems involved. During the last decade, the application of nanotechnological ... -
Applications of nanotechnology in diagnostics and therapeutics of Alzheimer's and Parkinson's disease
(2015)In this paper, an extended review analysis has been presented concerning the developments in brain drug delivery through new and efficient applications of nanotechnology. Modern nanotechnological approaches for the diagnosis ... -
Applied proteomics in companion animal medicine
(2016)Background: Proteomics in companion animal medicine has been used chiefly, in order to identify proteins, which may be used as biomarkers for early diagnosis of a variety of pathological conditions, as well as to elucidate ... -
Biomarkers for Alzheimer’s disease diagnosis
(2017)Objective: The dramatic increase in the population with dementia expected in the next decades is accompanied by the establishment of novel and innovated methods that will offer accurate and efficient detection of the disease ... -
Current status and future prospects of small–molecule protein–protein interaction (PPI) inhibitors of tumor necrosis factor (TNF) and receptor activator of NF-κB ligand (RANKL)
(2018)The overexpression of Tumor Necrosis Factor (TNF) is directly related to the development of several autoimmune diseases, such as rheumatoid and psoriatic arthritis, inflammatory bowel disease, Crohn’s disease, refractory ... -
The effect of strain hardening on the dynamic response of human artery segments
(2017)Background: When subjected to time-dependent blood pressure, human arteries undergo large deformations, exhibiting mainly nonlinear hyperelastic type of response. The mechanical response of arteries depends on the health ... -
Effects of yeast and bacterial commensals and pathogens of the female genital tract on the transepithelial electrical resistance of HeLa cells
(2016)Commensals of the human body can shift to a pathogenic phase when the host immune system is impaired. This study aims to investigate the effect of seven yeast and two bacterial commensals and opportunistic pathogens isolated ... -
The emerging role of helicobacter pylori-induced metabolic gastrointestinal dysmotility and neurodegeneration
(2017)Helicobacter pylori infection (Hp-I) is a prevalent disorder identified in themajority of the population in many countries around the world and is responsible for substantial gastrointestinal morbidity. Likewise, ... -
End-stage dementia spark of life: Reliability and validity of the “GATOS” questionnaire
(2015)Background: Floor effects are present in most dementia assessment tools as dementia progresses and the in–depth assessment of patients considered more or less on vegetative state is questionable. Objective: To develop a ... -
Epilepsy and neurosurgery: Historical highlights
(2017)Epilepsy has been known since antiquity and trepanation has been documented as a therapeutic option. The Greek born physician Aretaeus of Cappadocia (2nd century BC) was the first to recommend trepanation for the treatment ... -
Full blood count and peripheral arterial disease severity and prognosis
(2017)[No abstract available] -
Genes and conditions controlling mammalian pre-and post-implantation embryo development
(2015)Embryo quality during the in vitro developmental period is of great clinical importance. Experimental genetic studies during this period have demonstrated the association between specific gene expression profiles and the ... -
Historical hallmarks of anticoagulation and antiplatelet agents
(2016)Thrombosis is a well known phenomenon among physicians since antiquity. A variety of peculiar agents, such as leeches and bark, were used to prevent it. Hirudin was used during the 19th century. The next eon, heparin, ... -
The impact of combination therapy with a-blockers and 5ARIs on the progression of BPH
(2015)Benign prostatic hyperplasia (BPH) can be a progressive disease for some men with significant impact on their quality of life due to worsening of symptoms, risk of acute urinary retention (AUR) and surgery. Certain clinical ... -
Intra-renal hemodynamic changes after habitual physical activity in patients with chronic kidney disease
(2016)Background: Chronic Kidney Disease (CKD) is considered a silent epidemic with a continuously growing prevalence around the world. Due to uremia many functional and morphological abnormalities occur in almost all systems. ... -
Magnetic nanoparticles in medical diagnostic applications: Synthesis, characterization and proteins conjugation
(2016)Background: Magnetic nanoparticles (NPs) used in biomedical applications should be discrete with small particle sizes, narrow size distribution and superparamagnetic. NPs can be tailored to target, through chemical bonds, ... -
Management of blood pressure and heart rate in chronic kidney disease
(2017)Background: Hypertension is considered a major health problem in patients with chronic kidney disease (CKD) as approximately 80-85% of CKD patients’ suffer from hypertension in the United States. Hypertension is the second ... -
Mitochondrial dynamics and proteins related to neurodegenerative diseases
(2018)Disruptions in the regulation of mitochondrial dynamics and the occurrence of proteins misfolding lead to neuronal death, resulting in Age-related Dementia and Neurodegenerative diseases as well as Frailty. Functional, ...