Browsing by Subject "Allosteric Regulation"
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Glycogen phosphorylase revisited: Extending the resolution of the R- And T-state structures of the free enzyme and in complex with allosteric activators
(2021)The crystal structures of free T-state and R-state glycogen phosphorylase (GP) and of R-state GP in complex with the allosteric activators IMP and AMP are reported at improved resolution. GP is a validated pharmaceutical ...