Browsing by Subject "5 aryl 4 acyl 3 hydroxy 3 pyrrolin 2 one derivative"

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Multicomponent reaction of aldehydes, amines and oxalacetate analogues leading to biologically attractive pyrrole derivatives

Manta S., Kollatos N., Mitsos C., Chatzieffraimidi G.-A., Papanastasiou I., Gallos J.K., Komiotis D. (2020)

Pyrrole is a very important pharmacophoric moiety. It has been widely incorporated into the skeleton of antitumor, anti-inflammatory, antibacterial, antioxidant and antifungal active substances. Access to this key heterocycle ...