Browsing by Author "Orfanoudakis, G."
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Internal translation initiation stimulates expression of the ARF/core+1 open reading frame of HCV genotype 1b
Boumlic, A.; Vassilaki, N.; Dalagiorgou, G.; Kochlios, E.; Kakkanas, A.; Georgopoulou, U.; Markoulatos, P.; Orfanoudakis, G.; Mavromara, P. (2011)The hepatitis C virus possesses an alternative open reading frame overlapping the Core gene, whose products are referred to as Core+1 or alternative reading frame (ARF) or F protein(s). Extensive studies on genotype HCV-1 ... -
Molecular and evolutionary analysis of HPV16 E6 and E7 genes in Greek women
Tsakogiannis, D.; Papadopoulou, A.; Kontostathi, G.; Ruether, I. G. A.; Kyriakopoulou, Z.; Dimitriou, T. G.; Orfanoudakis, G.; Markoulatos, P. (2013)Human papillomavirus type 16 (HPV16) non-European variants have been associated with persistent infection and cervical cancer development, while the L83V variant of the E6 gene has been correlated with the progression of ... -
Prevalence of HPV16 E1-1374 boolean AND 63nt variants in Greek women
Tsakogiannis, D.; Kyriakopoulou, Z.; Darmis, F.; Ruether, I. G. A.; Dimitriou, T. G.; Orfanoudakis, G.; Panotopoulou, E.; Markoulatos, P. (2014)Recent studies have focused on sequence variation of the HPV16 E1 gene. The present study investigates the prevalence of E1-1374<^>63nt duplication in the Greek population, and the sequence variation at the 5 ' end of the ... -
Sites of disruption within E1 and E2 genes of HPV16 and association with cervical dysplasia
Tsakogiannis, D.; Gortsilas, P.; Kyriakopoulou, Z.; Ruether, I. G. A.; Dimitriou, T. G.; Orfanoudakis, G.; Markoulatos, P. (2015)Integration of HPV16 DNA into the host chromosome usually disrupts the E1 and/or E2 genes. The present study investigated the disruption of E1, E2 genes in a total of eighty four HPV16-positive precancerous and cervical ...