Browsing by Author "Asimaki, O."
Now showing items 1-5 of 5
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Cannabinoid 1 receptor-dependent transactivation of fibroblast growth factor receptor 1 emanates from lipid rafts and amplifies extracellular signal-regulated kinase 1/2 activation in embryonic cortical neurons
Asimaki, O.; Leondaritis, G.; Lois, G.; Sakellaridis, N.; Mangoura, D. (2011)G-protein coupled receptors may mediate their effects on neuronal growth and differentiation through activation of extracellular signal-regulated kinases 1/2 (ERK1/2), often elicited by transactivation of growth factor ... -
CB1R-dependent activation of Fyn tyrosine kinase and protein kinase C Delta, PKCδ, in lipid rafts
Asimaki, O.; Sakellaridis, N.; Mangoura, D. (2008)Cannabinoid 1 receptors (CB1Rs) are heptahelical transmembrane receptors which may exert their effects through the activation of the extracellular signal-regulated kinases (ERKs). We have previously shown that stably ... -
A CB1R-FGFR signaling module in plasma membrane lipid rafts is required for ERK activation in CNS neurons
Mangoura, D.; Sakellaridis, N.; Asimaki, O. (2010) -
PKC-epsilon activation is required for recognition memory in the rat
Zisopoulou, S.; Asimaki, O.; Leondaritis, G.; Vasilaki, A.; Sakellaridis, N.; Pitsikas, N.; Mangoura, D. (2013)Activation of PKC epsilon, an abundant and developmentally regulated PKC isoform in the brain, has been implicated in memory throughout life and across species. Yet, direct evidence for a mechanistic role for PKC epsilon ... -
Transactivation of epidermal growth factor receptor EGFR by CB1 cannabinoid receptor agonists
Asimaki, O.; Sakellaridis, N.; Mangoura, D. (2007)Cannabinoids have long been used as therapeutic agents. The recent identification of the endogenous cannabinoid system in the brain, namely the abundance of the CB1 receptor (CB1R) in the CNS and the discovery of the ...