Πλοήγηση ανά Συγγραφέα "Eleftheriadis T., Pissas G., Antoniadi G., Liakopoulos V., Stefanidis I."
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Allopurinol protects human glomerular endothelial cells from high glucose-induced reactive oxygen species generation, p53 overexpression and endothelial dysfunction
Eleftheriadis T., Pissas G., Antoniadi G., Liakopoulos V., Stefanidis I. (2018)Purpose: Mitochondrial reactive oxygen species (ROS) overproduction in capillary endothelial cells is a prerequisite for the development of diabetic nephropathy. Inhibition of xanthine oxidase, another ROS generator, ... -
Cell death patterns due to warm ischemia or reperfusion in renal tubular epithelial cells originating from human, mouse, or the native hibernator hamster
Eleftheriadis T., Pissas G., Antoniadi G., Liakopoulos V., Stefanidis I. (2018)Ischemia–reperfusion injury contributes to the pathogenesis of many diseases, with acute kidney injury included. Hibernating mammals survive prolonged bouts of deep torpor with a dramatic drop in blood pressure, heart, and ... -
A comparative analysis between proteasome and immunoproteasome inhibition in cellular and humoral alloimmunity
Eleftheriadis T., Pissas G., Antoniadi G., Liakopoulos V., Stefanidis I. (2017)Triggered by the successful administration of the proteasome inhibitor bortezomib in kidney transplant recipients with acute or chronic antibody-mediated rejection, we evaluated the effect of the proteasome inhibitor ... -
Kynurenine, by activating aryl hydrocarbon receptor, decreases erythropoietin and increases hepcidin production in HepG2 cells: A new mechanism for anemia of inflammation
Eleftheriadis T., Pissas G., Antoniadi G., Liakopoulos V., Stefanidis I. (2016)It is known that inadequate erythropoietin (EPO) production contributes to the pathogenesis of anemia of inflammation, although the exact molecular mechanism is unknown. Aryl hydrocarbon receptor (AhR) may compete with ... -
Proteasome or immunoproteasome inhibitors cause apoptosis in human renal tubular epithelial cells under normoxic and hypoxic conditions
Eleftheriadis T., Pissas G., Antoniadi G., Liakopoulos V., Stefanidis I. (2016)Purpose: Ischemic acute kidney injury is characterized by apoptosis of tubular epithelial cells. Proteasome plays a key role in cellular processes such as proliferation, apoptosis and inflammation. The results of animal ...