Auflistung Nach Schlagwort "adenine"

Association Between Level of Hepatitis D Virus RNA at Week 24 of Pegylated Interferon Therapy and Outcome

Keskin O., Wedemeyer H., Tüzün A., Zachou K., Deda X., Dalekos G.N., Heidrich B., Pehlivan S., Zeuzem S., Yalçin K., Gürel S., Tabak F., Idilman R., Bozkaya H., Manns M., Yurdaydin C. (2015)

Background & Aims: Interferon is the only effective treatment for chronic hepatitis D virus (HDV) infection. No rules have been set for stopping treatment based on viral kinetics. We analyzed data from an international ...

Clinical immunology quiz-Case 6

Speletas, M.; Boukas, K.; Louies, G.; Germenis, A. E. (2009)

Evidence for the molecular heterogeneity of sickle cell anemia chromosomes bearing the βS/benin haplotype

Patrinos, G. P.; Samperi, P.; Nigro, L. I.; Kollia, P.; Schiliro, G.; Papadakis, M. N. (2005)

There are at least four distinct African and one Asian chromosomal backgrounds (haplotypes) on which the sickle cell mutation has arisen. Additionally, previous data suggest that the βS/Bantu haplotype is heterogeneous at ...

In vivo base editing by a single i.v. vector injection for treatment of hemoglobinopathies

Li C., Georgakopoulou A., Newby G.A., Everette K.A., Nizamis E., Paschoudi K., Vlachaki E., Gil S., Anderson A.K., Koob T., Huang L., Wang H., Kiem H.-P., Liu D.R., Yannaki E., Lieber A. (2022)

Individuals with β-thalassemia or sickle cell disease and hereditary persistence of fetal hemoglobin (HPFH) possessing 30% fetal hemoglobin (HbF) appear to be symptom free. Here, we used a nonintegrating HDAd5/35++ vector ...

Tales around the clock: Poly(A) tails in circadian gene expression

Beta R.A.A., Balatsos N.A.A. (2018)

Circadian rhythms are ubiquitous time-keeping processes in eukaryotes with a period of ~24 hr. Light is perhaps the main environmental cue (zeitgeber) that affects several aspects of physiology and behaviour, such as ...

Targeted next-generation sequencing for the molecular diagnosis of hereditary angioedema due to C1-inhibitor deficiency

Loules G., Zamanakou M., Parsopoulou F., Vatsiou S., Psarros F., Csuka D., Porebski G., Obtulowicz K., Valerieva A., Staevska M., López-Lera A., López-Trascasa M., Moldovan D., Magerl M., Maurer M., Speletas M., Farkas H., Germenis A.E. (2018)

SERPING1 genotyping of subjects suspicious for hereditary angioedema due to C1-INH deficiency (C1-INH-HAE) is important for clinical practice as well as for research reasons. Conventional approaches towards the detection ...