• Mediterranean diet and risk for dementia and cognitive decline in a Mediterranean population 

      Charisis S., Ntanasi E., Yannakoulia M., Anastasiou C.A., Kosmidis M.H., Dardiotis E., Hadjigeorgiou G., Sakka P., Scarmeas N. (2021)
      Background: Current evidence suggests that nutrition in general and specific dietary patterns in particular, such as the Mediterranean type diet (MeDi), can be employed as potential preventive strategies against the ...
    • The nitric oxide donor molsidomine antagonizes age-related memory deficits in the rat 

      Pitsikas, N.; Rigamonti, A. E.; Cella, S. G.; Sakellaridis, N.; Muller, E. E. (2005)
      The effects of the nitric oxide (NO) donor molsidomine on aged rats' cognition were evaluated in two different behavioral tasks: the step-through passive avoidance paradigm and the object recognition test. Post-training ...
    • The novel dehydroepiandrosterone (DHEA) derivative BNN27 counteracts cognitive deficits induced by the D1/D2 dopaminergic receptor agonist apomorphine in rats 

      Pitsikas N., Zoupa E., Gravanis A. (2021)
      Rationale: Schizophrenia is a devastating mental disease that affects nearly 1% of the population worldwide. It is well documented that the dopaminergic (DAergic) system is compromised in schizophrenia. It is of note that ...
    • Objective and Subjective Measurements of Motor Function: Results from the HELIAD Study 

      Kalligerou F., Paraskevas G., Zalonis I., Kosmidis M.H., Yannakoulia M., Dardiotis E., Hadjigeorgiou G., Sakka P., Scarmeas N. (2022)
      Background: Slow gait speed has recently emerged as a potential prodromal feature of cognitive decline and dementia. Besides objective measurements, subjective motor function (SMF) difficulties might be present prior to ...
    • Pancultural nostalgia: Prototypical conceptions across cultures 

      Hepper, E. G.; Wildschut, T.; Sedikides, C.; Ritchie, T. D.; Yung, Y. F.; Hansen, N.; Abakoumkin, G.; Arikan, G.; Cisek, S. Z.; Demassosso, D. B.; Gebauer, J. E.; Gerber, J. P.; González, R.; Kusumi, T.; Misra, G.; Rusu, M.; Ryan, O.; Stephan, E.; J. Vingerhoets, A. J.; Zhou, X. (2014)
      Nostalgia is a frequently experienced complex emotion, understood by laypersons in the United Kingdom and United States of America to (a) refer prototypically to fond, self-relevant, social memories and (b) be more pleasant ...
    • Patterns of cognitive impairment in neurological disease 

      Markopoulou, K. (2010)
      Cognitive impairment is present in neurodegenerative disease, usually as part of a spectrum of symptoms that includes different domains of cognitive function. While the nature of the cognitive impairment tends to be ...
    • Reduced language abilities in adolescents who snore 

      Andreou, G.; Agapitou, P. (2007)
      Polysomnographic assessment of 20 adolescents who were referred to hospital for loud and frequent snoring showed they suffered from obstructive sleep apnea syndrome (OSAS). Their apneas and desaturation rates (SaO2) were ...
    • A roadmap towards a functional paradigm for learning & memory in plants 

      Michmizos D., Hilioti Z. (2019)
      In plants, the acquisition, processing and storage of empirical information can result in the modification of their behavior according to the nature of the stimulus, and yet this area of research remained relatively ...
    • The Role of Ketamine in Object Recognition Memory in Rodents 

      Pitsikas N. (2018)
      The object recognition test (ORT) was developed to assess the role of brain structures and neurochemical systems in memory processes in rodents, mainly rats and mice. It is based on spontaneous exploratory behaviour; hence ...
    • Simulating real-life exposures to uncover possible risks to human health: A proposed consensus for a novel methodological approach 

      Tsatsakis A.M., Kouretas D., Tzatzarakis M.N., Stivaktakis P., Tsarouhas K., Golokhvast K.S., Rakitskii V.N., Tutelyan V.A., Hernandez A.F., Rezaee R., Chung G., Fenga C., Engin A.B., Neagu M., Arsene A.L., Docea A.O., Gofita E., Calina D., Taitzoglou I., Liesivuori J., Hayes A.W., Gutnikov S., Tsitsimpikou C. (2017)
      In real life, consumers are exposed to complex mixtures of chemicals via food, water and commercial products consumption. Since risk assessment usually focuses on individual compounds, the current regulatory approach doesn't ...
    • Sleep and subjective cognitive decline in cognitively healthy elderly: Results from two cohorts 

      Tsapanou A., Vlachos G.S., Cosentino S., Gu Y., Manly J.J., Brickman A.M., Schupf N., Zimmerman M.E., Yannakoulia M., Kosmidis M.H., Dardiotis E., Hadjigeorgiou G., Sakka P., Stern Y., Scarmeas N., Mayeux R. (2019)
      Subjective cognitive decline may reflect a dementia prodrome or modifiable risk factor such as sleep disturbance. What is the association between sleep and subjective cognitive decline? Cross-sectional design, from two ...
    • Sleep polygenic risk score is associated with cognitive changes over time 

      Tsapanou A., Mourtzi N., Charisis S., Hatzimanolis A., Ntanasi E., Kosmidis M.H., Yannakoulia M., Hadjigeorgiou G., Dardiotis E., Sakka P., Stern Y., Scarmeas N. (2022)
      Sleep problems have been associated with cognition, both cross-sectionally and longitudinally. Specific genes have been also associated with both sleep regulation and cognition. In a large group of older non-demented adults, ...
    • Sleep quality and duration in relation to memory in the elderly: Initial results from the Hellenic Longitudinal Investigation of Aging and Diet 

      Tsapanou A., Gu Y., O'Shea D.M., Yannakoulia M., Kosmidis M., Dardiotis E., Hadjigeorgiou G., Sakka P., Stern Y., Scarmeas N. (2017)
      Background Sleep is crucial for cognition, particularly for memory, given its complex association with neurodegenerative processes. The aim of the present study was to examine the association between sleep quality as well ...
    • Subjective cognitive decline and rates of incident Alzheimer's disease and non–Alzheimer's disease dementia 

      Slot R.E.R., Sikkes S.A.M., Berkhof J., Brodaty H., Buckley R., Cavedo E., Dardiotis E., Guillo-Benarous F., Hampel H., Kochan N.A., Lista S., Luck T., Maruff P., Molinuevo J.L., Kornhuber J., Reisberg B., Riedel-Heller S.G., Risacher S.L., Roehr S., Sachdev P.S., Scarmeas N., Scheltens P., Shulman M.B., Saykin A.J., Verfaillie S.C.J., Visser P.J., Vos S.J.B., Wagner M., Wolfsgruber S., Jessen F., Boada M., de Deyn P.P., Jones R., Frisoni G., Spiru L., Nobili F., Freund-Levi Y., Soininen H., Verhey F., Wallin Å.K., Touchon J., Rikkert M.O., Rigaud A.-S., Bullock R., Tsolaki M., Vellas B., Wilcock G., Froelich L., Bakardjian H., Benali H., Bertin H., Bonheur J., Boukadida L., Boukerrou N., Chiesa P., Colliot O., Dubois B., Dubois M., Epelbaum S., Gagliardi G., Genthon R., Habert M.-O., Houot M., Kas A., Lamari F., Levy M., Metzinger C., Mochel F., Nyasse F., Poisson C., Potier M.-C., Revillon M., Santos A., Andrade K.S., Sole M., Surtee M., Thiebaud de Schotten M., Vergallo A., Younsi N., van der Flier W.M., Alzheimer's Disease Neuroimaging Initiative, DESCRIPA working group, INSIGHT-preAD study group, SCD-I working group (2019)
      Introduction: In this multicenter study on subjective cognitive decline (SCD) in community-based and memory clinic settings, we assessed the (1) incidence of Alzheimer's disease (AD) and non-AD dementia and (2) determinants ...
    • Synaptic Plasticity: A Unifying Model to Address Some Persisting Questions 

      Michmizos, D.; Koutsouraki, E.; Asprodini, E.; Baloyannis, S. (2011)
      Since it was first observed, synaptic plasticity has been considered as the experimental paradigm most likely to provide us with an understanding of how information is stored in the vertebrate brain. Various types have ...