Πλοήγηση ανά Θέμα "Virology"
Αποτελέσματα 21-40 από 40
-
Low Oxygen Tension Enhances Hepatitis C Virus Replication
(2013)Low oxygen tension exerts a significant effect on the replication of several DNA and RNA viruses in cultured cells. In vitro propagation of hepatitis C virus (HCV) has thus far been studied under atmospheric oxygen levels ... -
Molecular and phylogenetic analysis of haemagglutinin and neuraminidase sequences from recent human influenza type A (H3N2) viral isolates in Southern Greece
(2001)Eighteen haemagglutinin (HAI) gene segments and eleven neuraminidase (NA) genes of human influenza type A (H3N2) viruses isolated from non-vaccinated individuals presenting severe influenza-like illness at peak influenza ... -
Molecular and phylogenetic analysis of the HPV 16 E4 gene in cervical lesions from women in Greece
(2012)The HPV16 E1(a )E4 protein is thought to contribute to the release of newly formed viral particles from infected epithelia. In order to investigate amino acid mutations in the HPV16 E1(a )E4 protein, the complete E4 ORF ... -
Molecular characterization of a new intergenotype Norovirus GII recombinant
(2012)Human noroviruses (NoVs) of the Caliciviridae family are a major cause of epidemic gastroenteritis. The NoV genus is genetically diverse and recombination of viral RNA is known to depend upon various immunological and ... -
Molecular identification and full genome analysis of an echovirus 7 strain isolated from the environment in Greece
(2010)Two enteroviruses from river water and four from sewage treatment plant were isolated in Larissa, Greece, that all shared the same sequence. A full genome analysis was conducted in an attempt to reveal the evolutionary ... -
Molecular phylogeny of VP1, 2A, and 2B genes of echovirus isolates: epidemiological linkage and observations on genetic variation
(2006)Phylogenetic relationships between 37 echovirus clinical isolates, most of them originating from an aseptic meningitis outbreak during 2001 in Greece, were investigated by RT-PCR and sequencing. The generic primers 292 and ... -
Nucleotide analysis and phylogenetic study of the homology boundaries of coxsackie A and B viruses
(2005)Modern molecular methods use VP1 coding region as a target for RT-PCR assays followed by sequencing, in order to identify new untyped enteroviruses' strains. In the present study, two different genomic portions of VP1 and ... -
Nucleotide polymorphisms of the human papillomavirus 16 E1 gene
(2014)The E1 ORF is one of the most conserved regions in the human papillomavirus (HPV) genome. The complete E1 gene of the HPV16 genome was amplified with four overlapping primer sets in 16 high-grade (CIN II, III) and 13 ... -
Pathological Evaluation of Reproductive System of Porcine Reproductive and Respiratory Syndrome Virus-Vaccinated and Nonvaccinated Anestrus Sows and Gilts
(2015)The purpose of the study was to evaluate pathologically the reproductive system of nonvaccinated and porcine reproductive and respiratory syndrome virus (PRRSV)-vaccinated sows/gilts, as well as the assessment of vaccination ... -
Phylogenetic analysis of strains of Orf virus isolated from two outbreaks of the disease in sheep in Greece
(2012)Background: Although orf is endemic around the world, there are few descriptions of Orf virus strains and comparisons of these strains. We report the sequence and phylogenetic analysis of the partial B2L gene of Orf virus ... -
Polymorphisms of Cx(3)CR1 and CXCR6 receptors in relation to HAART therapy of HIV type 1 patients
(2007)The chemokine polymorphisms CXCR6-3E/K, In1.1T/C, H7 haplotype, CX(3)CR1-V249I, and CX(3)CR1-T280M have been shown to affect the course of HIV infection. We studied their influence on immunologic and virologic response to ... -
Prevalence of HPV16 E1-1374 boolean AND 63nt variants in Greek women
(2014)Recent studies have focused on sequence variation of the HPV16 E1 gene. The present study investigates the prevalence of E1-1374<^>63nt duplication in the Greek population, and the sequence variation at the 5 ' end of the ... -
Real-time quantification of human telomerase reverse transcriptase mRNA in liver tissues from patients with hepatocellular cancer and chronic viral hepatitis
(2007)We determined, for the first time, the human telomerase reverse transcriptase (hTERT) mRNA expression, using real-time quantitative PCR, in liver tissues from patients with hepatocellular cancer (HCC; n = 13), chronic ... -
Recombination among human non-polio enteroviruses: implications for epidemiology and evolution
(2015)Human enteroviruses (EV) belong to the Picornaviridae family and are among the most common viruses infecting humans. They consist of up to 100 immunologically and genetically distinct types: polioviruses, coxsackieviruses ... -
Role of siderophores in cystic fibrosis pathogenesis: Foes or friends?
(2009)Cystic fibrosis (CF) is one of the most common genetic disorders among Caucasians. CF patients are susceptible to chronic lung infections caused by diverse microorganisms, therefore CF should be regarded as a polymicrobial ... -
Safety and efficacy of lamivudine in patients with severe acute or fulminant hepatitis B, a multicenter experience
(2006)Acute hepatitis B progresses to liver failure with the need of liver transplantation in about 1% of cases. We treated patients with severe acute or fulminant hepatitis B with lamivudine in an attempt to prevent hepatitis ... -
Sequence variation analysis of the E2 gene of human papilloma virus type 16 in cervical lesions from women in Greece
(2012)The E2 gene of human papilloma virus is expressed at the early stage of the viral life cycle, encoding the E2 transcription factor, and regulates the expression of E6 and E7 oncogenes. Disruption of E2 gene due to viral ... -
Serological and molecular investigation into the role of wild birds in the epidemiology of West Nile virus in Greece
(2012)Background: A West Nile virus (WNV) disease outbreak occurred in 2010 in northern Greece with a total of 262 laboratory-confirmed human cases and 35 deaths. A serological and molecular surveillance was conducted on samples ... -
Sites of disruption within E1 and E2 genes of HPV16 and association with cervical dysplasia
(2015)Integration of HPV16 DNA into the host chromosome usually disrupts the E1 and/or E2 genes. The present study investigated the disruption of E1, E2 genes in a total of eighty four HPV16-positive precancerous and cervical ... -
Telomerase reverse transcriptase mRNA expression in peripheral lymphocytes of patients with chronic HBV and HCV infections
(2005)Telomerase activity is present at low levels in peripheral lymphocytes (PL) and is upregulated upon activation, possibly protecting PL from telomere shortening. As decreased telomere length is considered a sign of cellular ...