Browsing by Title

Lack of an association between SCFD1 rs10139154 polymorphism and amyotrophic lateral sclerosis

Siokas V., Aloizou A.-M., Liampas I., Bakirtzis C., Nasios G., Paterakis K., Sgantzos M., Bogdanos D.P., Spandidos D.A., Tsatsakis A., Mitsias P.D., Dardiotis E. (2022)

Amyotrophic lateral sclerosis (AL S) is a progressive neurodegenerative disease. Through a genome-wide association study (GWAS), the Sec1 family domain-containing protein 1 (SCFD1) rs10139154 variant at 14q12 has emerged ...

Lack of association between appendectomy and primary biliary cirrhosis

Rigopoulou, E. I.; Georgiadou, S. P.; Barbanis, S.; Dalekos, G. N. (2006)

Objective. In view of the possible implication of various environmental factors in the pathogenesis of primary biliary cirrhosis (PBC), the role of appendectomy in patients with PBC and other chronic liver diseases from ...

Lack of association between claw lesions or claw overgrowth and inflammation of the urinary bladder of culled sows from Greek herds

Skampardonis V., Cernat M., Papadopoulos G.A., Kroustallas F., Chalvatzi S., Psychas V., Marouda C., Fortomaris P., Leontides L. (2022)

Factors associated with decreased frequency of micturition appeared to predispose sows to urinary tract infections (UTI) which are characterized by cystitis, ureteritis and pyelonephritis. We aimed to investigate the ...

Lack of Association Between Common Endothelial Nitric Oxide Synthase Gene Haplotypes and Left Ventricular Hypertrophy in Hypertension

Kitsios, G. D.; Stefanidis, I.; Zintzaras, E. (2010)

The endothelial nitric oxide synthase (NOS3) gene has been implicated in the pathogenesis of hypertension-related left ventricular hypertrophy (LVH). Candidate-gene studies have examined the role of NOS3 variation, but ...

Lack of association between retention of fetal membranes and mastitis in ewes

Leontides, L.; Fthenakis, G. C.; Tzora, A. (2001)

Lack of association between the UDP-glucuronosyltransferase 1A1 (UGT1A1) gene polymorphism and the risk of benign prostatic hyperplasia in Caucasian men

Karatzas, A.; Tzortzis, V.; Giannatou, E.; Gravas, S.; Zachos, I.; Oeconomou, A.; Melekos, M.; Tsezou, A. (2013)

Glucuronidation, mediated by the UDP-glucuronosyltransferase 1A1 (UGT1A1) enzyme, is an important metabolic process during which steroids are converted to more easily excreted compounds in steroid target tissues, such as ...

Lack of association between TREM2 rs75932628 variant and amyotrophic lateral sclerosis

Siokas V., Aloizou A.-M., Liampas I., Tsouris Z., Mentis A.-F.A., Nasios G., Papadimitriou D., Bogdanos D.P., Hadjigeorgiou G.M., Dardiotis E. (2021)

Amyotrophic lateral sclerosis (ALS) is a multifactorial neurodegenerative disease. Inflammatory processes are among the mechanisms that are implicated in ALS pathogenesis. The TREM2 rs75932628 T variant may influence the ...

Lack of association of acute phase response proteins with hormone levels and antidepressant medication in perimenopausal depression

Karaoulanis, S. E.; Rizouli, K. A.; Rizoulis, A. A.; Angelopoulos, N. V. (2014)

Background: Major depression is associated with higher plasma levels of positive acute-phase proteins, as well as with lower plasma levels of negative acute-phase proteins. The aim of this study is to examine the levels ...

Lack of association of single nucleotide polymorphism in LRCH1 with knee osteoarthritis susceptibility

Jiang, Q.; Shi, D.; Nakajima, M.; Dai, J.; Wei, J.; Malizos, K. N.; Qin, J.; Miyamoto, Y.; Kamatani, N.; Liu, B.; Tsezou, A.; Nakamura, T.; Ikegawa, S. (2008)

A genetic association of knee osteoarthritis (OA) and a C/T transition single nucleotide polymorphism (SNP) (rs912428) located in intron 1 of the LRCH1 gene has recently been reported in European Caucasians; however, the ...

Lack of Association of the rs11655081 ARSG Gene with Blepharospasm

Siokas V., Kardaras D., Aloizou A.-M., Asproudis I., Boboridis K.G., Papageorgiou E., Spandidos D.A., Tsatsakis A., Tsironi E.E., Dardiotis E. (2019)

Blepharospasm (BSP) is a sub-phenotype of focal dystonia. A few genetic risk factors are considered to be implicated in the risk of developing BSP. There is recent evidence, based on results from GWAS and meta-analyses, ...

Lack of Association of the UCHL-1 Gene with Parkinson's Disease in a Greek Cohort: A Haplotype-Tagging Approach

Xiromerisiou, G.; Kyratzi, E.; Dardiotis, E.; Bozi, M.; Tsimourtou, V.; Stamboulis, E.; Ralli, S.; Vassilatis, D.; Gourbali, V.; Kountra, P. M.; Fountas, K.; Papadimitriou, A.; Stefanis, L.; Hadjigeorgiou, G. M. (2011)

Lack of evidence for a genetic association between FGF20 and Parkinson's disease in Finnish and Greek patients

Clarimon, J.; Xiromerisiou, G.; Eerola, J.; Gourbali, V.; Hellstrom, O.; Dardiotis, E.; Peuralinna, T.; Papadimitriou, A.; Hadjigeorgiou, G. M.; Tienari, P. J.; Singleton, A. B. (2005)

Background: Fibroblast growth factor 20 (FGF20) is a neurotrophic factor preferentially expressed in the substantia nigra of rat brain and could be involved in dopaminergic neurons survival. Recently, a strong genetic ...

Lack of macroscopically evident cardiac regeneration or spontaneous functional recovery in infarcted neonatal pigs

Malliaras K., Polychronopoulou E., Poulakida I., Sagris D., Makaritsis K. (2020)

[No abstract available]

Lack of pseudouridine 38/39 in the anticodon arm of yeast cytoplasmic tRNA decreases in vivo recoding efficiency

Lecointe, F.; Namy, O.; Hatin, I.; Simos, G.; Rousset, J. P.; Grosjean, H. (2002)

Many different modified nucleotides are found in naturally occurring tRNA, especially in the anticodon region. Their importance for the efficiency of the translational process begins to be well documented. Here we have ...

Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study

Elbaz, A.; Nelson, L. M.; Payami, H.; Ioannidis, J. P.; Fiske, B. K.; Annesi, G.; Carmine Belin, A.; Factor, S. A.; Ferrarese, C.; Hadjigeorgiou, G. M.; Higgins, D. S.; Kawakami, H.; Krüger, R.; Marder, K. S.; Mayeux, R. P.; Mellick, G. D.; Nutt, J. G.; Ritz, B.; Samii, A.; Tanner, C. M.; Van Broeckhoven, C.; Van Den Eeden, S. K.; Wirdefeldt, K.; Zabetian, C. P.; Dehem, M.; Montimurro, J. S.; Southwick, A.; Myers, R. M.; Trikalinos, T. A. (2006)

Background: A genome-wide association study identified 13 single-nucleotide polymorphisms (SNPs) significantly associated with Parkinson's disease. Small-scale replication studies were largely non-confirmatory, but a ...

Lack of synergistic nephrotoxicity between vancomycin and piperacillin/tazobactam in a rat model and a confirmatory cellular model

Pais G.M., Liu J., Avedissian S.N., Hiner D., Xanthos T., Chalkias A., D'Aloja E., Locci E., Gilchrist A., Prozialeck W.C., Rhodes N.J., Lodise T.P., Fitzgerald J.C., Downes K.J., Zuppa A.F., Scheetz M.H. (2020)

Vancomycin and piperacillin/tazobactam are reported in clinical studies to increase acute kidney injury (AKI). However, no clinical study has demonstrated synergistic toxicity, only that serum creatinine increases. To ...

Lack of validation of genetic variants associated with anti-tumor necrosis factor therapy response in rheumatoid arthritis: a genome-wide association study replication and meta-analysis

Marquez, A.; Ferreiro-Iglesias, A.; Davila-Fajardo, C. L.; Montes, A.; Pascual-Salcedo, D.; Perez-Pampin, E.; Moreno-Ramos, M. J.; Garcia-Portales, R.; Navarro, F.; Moreira, V.; Magro, C.; Caliz, R.; Ferrer, M. A.; Alegre-Sancho, J. J.; Joven, B.; Carreira, P.; Balsa, A.; Vasilopoulos, Y.; Sarafidou, T.; Cabeza-Barrera, J.; Narvaez, J.; Raya, E.; Canete, J. D.; Fernandez-Nebro, A.; Ordonez, M. D.; de la Serna, A. R.; Magallares, B.; Gomez-Reino, J. J.; Gonzalez, A.; Martin, J. (2014)

Introduction: In this study, our aim was to elucidate the role of four polymorphisms identified in a prior large genome-wide association study (GWAS) in which the investigators analyzed the responses of patients with ...

Laconian Vase painter of 6th century

Paleothodoros, D. (2007)

Lactate dehydrogenase isoenzymes in patients with acute exacerbation of chronic obstructive pulmonary disease: An exploratory cross-sectional study

Skopas V., Papadopoulos D., Trakas N., Papaefstathiou E., Koufopoulos C., Makris D., Daniil Z., Gourgoulianis K. (2021)

We aimed to evaluate differences in serum lactate dehydrogenase (LDH) isoenzymes between patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and other lower respiratory tract ...

LaGomiCs - Lagomorph Genomics Consortium: An International Collaborative Effort for Sequencing the Genomes of an Entire Mammalian Order

Fontanesi L., Di Palma F., Flicek P., Smith A.T., Thulin C.-G., Alves P.C., Abrantes J., Andersson L., Angelone C., Boonstra R., Campos R., Carneiro M., Casadio R., Cervantes F.A., Dahal N., Djan M., Esteves P.J., Etherington G., Fan J., Fickel J., Ge D., Husband T., King T., Kovach A.I., Lavazza A., Letty J., Lissovsky A.A., Mage R., Mamuris Z., Martelli P.L., McGreevy T., Jr., Melo-Ferreira J., Muffato M., Ramakrishnan U., Randi E., Reid N., Ribani A., Robinson T.J., Russello M.A., Schiavo G., Schneider-Gricar V., Solari K.A., Streeter I., Tizzani P., Tur A., Utzeri V.J., Velickovic N., Vernesi C., Yang Q., Lagomorph Genomics Consortium (2016)

The order Lagomorpha comprises about 90 living species, divided in 2 families: the pikas (Family Ochotonidae), and the rabbits, hares, and jackrabbits (Family Leporidae). Lagomorphs are important economically and scientifically ...