Πλοήγηση ανά Συγγραφέα "Spandidos, D. A."
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Loss of heterozygosity in DNA mismatch repair genes in human atherosclerotic plaques
Flouris, G. A.; Arvanitis, D. A.; Parissis, J. T.; Arvanitis, D. L.; Spandidos, D. A. (2001)To detect the incidence of loss of heterozygosity (LOH) in DNA mismatch repair genes (MMR) occurring in atherosclerosis, fifty human autopsy cases of atherosclerosis were examined for LOH using 19 microsatellite markers, ... -
Microsatellite instability in human atherosclerotic plaques
Spandidos, D. A.; Ergazaki, M.; Arvanitis, D.; Kiaris, H. (1996)The aetiopathology of atherosclerosis remains obscure. Although histologically the accumulation of lipids and the proliferation of the smooth muscle cells represents the main feature of the disease, little is known as ... -
Miliary tuberculosis with no pulmonary involvement in myelodysplastic syndromes: A curable, yet rarely diagnosed, disease: Case report and review of the literature
Neonakis, I. K.; Alexandrakis, M. G.; Gitti, Z.; Tsirakis, G.; Krambovitis, E.; Spandidos, D. A. (2008)Background: Although tuberculosis is not uncommon among patients with myelodysplastic syndrome (MDS), only a few reports of such patients suffering from miliary tuberculosis (MT) exist. MT often presents as a fever of ... -
Molecular diagnostic tools in mycobacteriology
Neonakis, I. K.; Gitti, Z.; Krambovitis, E.; Spandidos, D. A. (2008)Although the diagnosis of mycobacteriosis and susceptibility testing are still primarily based on conventional methods (staining, culture, biochemical analysis, proportional method), a series of molecular assays are ... -
Mycobacterial species diversity at a general hospital on the island of Crete: First detection of Mycobacterium lentiflavum in Greece
Neonakis, I. K.; Gitti, Z.; Kourbeti, I. S.; Michelaki, H.; Baritaki, M.; Alevraki, G.; Papadomanolaki, E.; Tsafaraki, E.; Tsouri, A.; Baritaki, S.; Krambovitis, E.; Spandidos, D. A. (2007)The objective of the present study was to investigate the diversity of mycobacterial isolates in a general hospital in Crete, Greece. 48 positive Lowenstein-Jensen cultures over a 3-y period were analysed by means of ... -
Mycobacterium arupense pulmonary infection: Antibiotic resistance and restriction fragment length polymorphism analysis
Neonakis, I. K.; Gitti, Z.; Kontos, F.; Baritaki, S.; Petinaki, E.; Baritaki, M.; Liakou, V.; Zerva, L.; Spandidos, D. A. (2010)Mycobacterium arupense is a novel mycobacterium species. It was first identified from clinical specimens in 2006 and since then there have been only two reports of its recovery from clinical samples. In the present case ... -
Mycobacterium thermoresistibile: Case report of a rarely isolated mycobacterium from Europe and review of literature
Neonakis, I. K.; Gitti, Z.; Kontos, F.; Baritaki, S.; Petinaki, E.; Baritaki, M.; Zerva, L.; Spandidos, D. A. (2009)Mycobacterium thermoresistibile is a non-tuberculous mycobacterium strongly associated with human infections. Since 1966, there have only been six reports of its isolation from clinical samples. We report on the first case ... -
Polymorphisms of Cx(3)CR1 and CXCR6 receptors in relation to HAART therapy of HIV type 1 patients
Passam, A. M.; Sourvinos, G.; Krambovitis, E.; Miyakis, S.; Stavrianeas, N.; Zagoreos, I.; Spandidos, D. A. (2007)The chemokine polymorphisms CXCR6-3E/K, In1.1T/C, H7 haplotype, CX(3)CR1-V249I, and CX(3)CR1-T280M have been shown to affect the course of HIV infection. We studied their influence on immunologic and virologic response to ... -
Polyphenolic composition of grape stem extracts affects antioxidant activity in endothelial and muscle cells
Goutzourelas, N.; Stagos, D.; Spanidis, Y.; Liosi, M.; Apostolou, A.; Priftis, A.; Haroutounian, S.; Spandidos, D. A.; Tsatsakis, A. M.; Kouretas, D. (2015)The aim of the present study was the assessment of the antioxidant effects of polyphenolic extracts derived from the stems of three Greek grape varieties (Moshomayro, Mavrotragano and Mandilaria) in endothelial (EA.hy926) ... -
A primary cardiac leiomyosarcoma with mutation at H-ras codon 12
Parissis, J.; Arvanitis, D. L.; Sourvinos, G.; Spandidos, D. A. (1997)The presence of activating ras mutations in a cardiac leiomyosarcoma which occurred in the right atrium of the heart of a female patient was examined. The tumor had the appearance of leiomyosarcoma in rutine histopathological ... -
Protein and mRNA expression levels of VEGF-A and TGF-B1 in different types of human coronary atherosclerotic lesions
Panutsopulos, D.; Papalambros, E.; Sigala, F.; Zafiropoulos, A.; Arvanitis, D. L.; Spandidos, D. A. (2005)It is well documented that inflammation plays a major role in the establishment and progression of atherosclerosis. Endothelial cells, vascular smooth muscle cells and m onocytes/macrophages are involved in this process ... -
RANTES promoter gene polymorphisms and susceptibility to severe respiratory syncytial virus-induced bronchiolitis
Amanatidou, V.; Sourvinos, G.; Apostolakis, S.; Neonaki, P.; Tsilimigaki, A.; Krambovitis, E.; Spandidos, D. A. (2008)Background: Severe respiratory syncytial virus (RSV) infection is characterized by enhanced chemokine activity. Several studies have linked increased regulated on activation, normal T cell expressed and secreted (RANTES) ... -
Report of 2 indigenous cases of leprosy from a European country: use of polymerase chain reaction-restriction fragment length polymorphism analysis of hsp65 gene for identification of Mycobacterium leprae directly from a clinical sample
Neonakis, I. K.; Gitti, Z.; Kontos, F.; Baritaki, S.; Zerva, L.; Krambovitis, E.; Spandidos, D. A. (2009)In this article, we report on 2 indigenous cases of leprosy detected in a European country. We also report on the use of polymerase chain reaction-restriction fragment length polymorphism analysis of hsp65 gene for rapid ... -
Resistance status of Mycobacterium tuberculosis on the island of Crete, Greece
Neonakis, I. K.; Gitti, Z.; Baritaki, M.; Kourbeti, I. S.; Baritaki, S.; Petinaki, E.; Maraki, S.; Krambovitis, E.; Spandidos, D. A. (2007) -
Use of loop-mediated isothermal amplification of DNA for the rapid detection of Mycobacterium tuberculosis in clinical specimens
Neonakis, I. K.; Spandidos, D. A.; Petinaki, E. (2011)Loop-mediated isothermal amplification (LAMP) is a recently developed molecular method that has been successfully implemented in the detection of Mycobacterium tuberculosis in clinical specimens. LAMP has several advantages, ...