Posterior reversible encephalopathy in a GT1a positive oculopharyngeal variant of Guillain-Barré syndrome: A case-report and review of the literature
Date
2020Language
en
Sujet
Résumé
Guillain-Barre syndrome (GBS) is the most common cause of acute flaccid paralysis and its incidence increases with age, although all age groups can be affected. The cranial subtypes of GBS account for approximately 5% of cases. Posterior reversible encephalopathy syndrome (PRES) is an acute neurological disorder, mostly reversible but with increased morbidity with permanent neurological sequelae in severe cases. The coexistence of these two syndromes is very rare and underdiagnosed. To the best of our knowledge, there are several dozen cases reported in the literature including ours with the coexistence of these two syndromes in adult patients. We present a rare case of oculopharyngeal type of GBS followed by PRES syndrome. Based on the reviewed cases we discuss various pathogenic mechanisms that support the association between these two entities. This review illustrates the importance of detecting PRES syndrome in the context of acute inflammatory immune-mediated polyneuropathies especially when the patients present early dysautonomia. We also discuss the importance of early administration of immunoglobulin (IVIG) treatment but the possible risks that poses to the occurrence of PRES syndrome as well. © 2020 Elsevier B.V.
Collections
Related items
Showing items related by title, author, creator and subject.
-
Association between Helicobacter pylori infection and Guillain-Barré Syndrome: A meta-analysis
Dardiotis E., Sokratous M., Tsouris Z., Siokas V., Mentis A.-F.A., Aloizou A.-M., Michalopoulou A., Bogdanos D.P., Xiromerisiou G., Deretzi G., Kountouras J., Hadjigeorgiou G.M. (2020)Background: Helicobacter pylori (H pylori) is a Gram-negative bacterium, considered to trigger autoimmune gastrointestinal disorders. This pathogen has also been linked to the autoimmune sequelae in extra-gastrointestinal ... -
Non-alcoholic steatohepatitis or autoimmune hepatitis? Sometimes a closer look under the surface is needed
Dalekos G.N., Gatselis N.K., Koukoulis G.K. (2020)Non-alcoholic fatty liver disease (NAFLD) is nowadays the most common liver disease worldwide. Autoimmune hepatitis (AIH) is a relatively rare disease of the liver characterised by female predominance, circulating ... -
(2-Heremans-schmid glycoprotein (fetuin A) downregulation and its utility in inflammatory bowel disease
Manolakis A.C., Christodoulidis G., Kapsoritakis A.N., Georgoulias P., Tiaka E.K., Oikonomou K., Valotassiou V.J., Potamianos S.P. (2017)AIM: To investigate the impact of inflammatory bowel disease (IBD) on α2-Heremans-Schmid Glycoprotein (AHSG/fetuin A) and potential associations with disease and patient characteristics. METHODS: AHSG serum levels were ...