Pneumonia with empyema among children in the first five years of high coverage with 13-valent pneumococcal conjugate vaccine
dc.creator | Syrogiannopoulos G.A., Michoula A.N., Tsimitselis G., Vassiou K., Chryssanthopoulou D.C., Grivea I.N. | en |
dc.date.accessioned | 2023-01-31T10:05:22Z | |
dc.date.available | 2023-01-31T10:05:22Z | |
dc.date.issued | 2016 | |
dc.identifier | 10.1080/23744235.2016.1192720 | |
dc.identifier.issn | 23744235 | |
dc.identifier.uri | http://hdl.handle.net/11615/79558 | |
dc.description.abstract | Abstract: Background: Parapneumonic effusions in children are usually associated with pneumococcal infections. In Greece, the 7-valent pneumococcal conjugate vaccine was replaced by higher-valent pneumococcal conjugate vaccines (PCVs); 10-valent was introduced in May 2009 and 13-valent (PCV13) in June 2010. Since July 2010, PCV13 has been the most commonly used PCV. In a study conducted at the University General Hospital of Larissa, Central Greece, from January 2012 to January 2016, 85.7% of children born after the implementation of PCV13 and aged 24–59 months had received the complete series (3 + 1 immunization schedule) of PCV13. Methods: We studied all paediatric community-acquired pneumonia cases with empyema hospitalized at the University General Hospital of Larissa from January 2008 to January 2016. Results: There were 30 cases of parapneumonic empyema. Among 27 empyema cases of known aetiology, 19 (70.4%) were due to Streptococcus pneumoniae (identifiable serotypes 3, 19A, 7F, and 9N/L). After September 2011, no more cases caused by serotypes 7F and 19A were observed, whereas serotype 3 emerged as the predominant pathogen of pneumococcal empyema (9 of 11 cases). Serotype 3 continued to cause empyema despite vaccination with PCV13 either fully with a 3 + 1 schedule (n = 3) or with one booster dose at the age of 21 months (n = 1). Conclusion: In Central Greece during the first five years of high coverage with PCV13, serotype 3 was the only PCV13 serotype that clearly persisted in children with empyema. © 2016 Society for Scandinavian Journal of Infectious Diseases. | en |
dc.language.iso | en | en |
dc.source | Infectious Diseases | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84978496366&doi=10.1080%2f23744235.2016.1192720&partnerID=40&md5=ebd1bb5ed88cb404022c246f552c2b48 | |
dc.subject | Pneumococcus vaccine | en |
dc.subject | 13-valent pneumococcal vaccine | en |
dc.subject | Pneumococcus vaccine | en |
dc.subject | Article | en |
dc.subject | child | en |
dc.subject | childhood disease | en |
dc.subject | clinical article | en |
dc.subject | community acquired pneumonia | en |
dc.subject | empyema | en |
dc.subject | female | en |
dc.subject | general hospital | en |
dc.subject | Greece | en |
dc.subject | hospitalized child | en |
dc.subject | human | en |
dc.subject | immunization | en |
dc.subject | male | en |
dc.subject | observational study | en |
dc.subject | preschool child | en |
dc.subject | prospective study | en |
dc.subject | serotype | en |
dc.subject | Streptococcus pneumoniae | en |
dc.subject | university hospital | en |
dc.subject | vaccination | en |
dc.subject | classification | en |
dc.subject | complication | en |
dc.subject | empyema | en |
dc.subject | infant | en |
dc.subject | isolation and purification | en |
dc.subject | microbiology | en |
dc.subject | newborn | en |
dc.subject | Pneumonia, Pneumococcal | en |
dc.subject | serotype | en |
dc.subject | utilization | en |
dc.subject | Child | en |
dc.subject | Child, Preschool | en |
dc.subject | Empyema | en |
dc.subject | Female | en |
dc.subject | Greece | en |
dc.subject | Hospitals, University | en |
dc.subject | Humans | en |
dc.subject | Infant | en |
dc.subject | Infant, Newborn | en |
dc.subject | Male | en |
dc.subject | Pneumococcal Vaccines | en |
dc.subject | Pneumonia, Pneumococcal | en |
dc.subject | Prospective Studies | en |
dc.subject | Serogroup | en |
dc.subject | Streptococcus pneumoniae | en |
dc.subject | Vaccination | en |
dc.subject | Taylor and Francis Ltd. | en |
dc.title | Pneumonia with empyema among children in the first five years of high coverage with 13-valent pneumococcal conjugate vaccine | en |
dc.type | journalArticle | en |
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