dc.creator | Morres I.D., Tzouma N.-A., Hatzigeorgiadis A., Krommidas C., Kotronis K.V., Dafopoulos K., Theodorakis Y., Comoutos N. | en |
dc.date.accessioned | 2023-01-31T09:01:18Z | |
dc.date.available | 2023-01-31T09:01:18Z | |
dc.date.issued | 2022 | |
dc.identifier | 10.1016/j.jad.2021.10.124 | |
dc.identifier.issn | 01650327 | |
dc.identifier.uri | http://hdl.handle.net/11615/76745 | |
dc.description.abstract | Background: Exercise improves perinatal depressive (PD) symptoms, but reports call for more robust evidence. This systematic review and meta-analysis aimed at synthesizing evidence exclusively from randomized controlled trials (RCTs) examining the effects of exercise on PD symptoms in women recruited through perinatal health services. Methods: Nine e-databases and fifteen systematic reviews were searched for relevant RCTs. Exercise-specific tools extracted/coded data. A meta-analysis using a random effects model (Standardized Mean Difference [SMD]) investigated the effects of exercise on PD scores post-intervention. Results: From 285 records, 14 RCTs (2.025 participants) were considered eligible including two RCTs with clinically diagnosed PD women. Exercise showed a statistically significant, small, overall antidepressant effect (SMD = -0.21, 95% CI = -0.31, -0.11, p = 0.0001) with low/non-significant heterogeneity (Q = 17.82, I 2 = 16%, p = 0.27). Only the fail-safe criterion recorded marginally significant publication bias, but trim-fill analysis added no study. Sensitivity analyses increased the overall effect in RCTs showing lower risk of bias or delivering ≥150 min/week moderate intensity aerobic exercise. Subgroup analyses revealed significant antidepressant effects for exercise across various settings, delivery formats, depressive symptoms severities and outcome measures used. Heterogeneity was low/non-significant in all analyses (I 2 ≤ 50%). Hedges’ g corrections did not influence the results. Limitations: Study limitations include the small number of available trials and clinically diagnosed PD samples and the variety of exercise modalities. Conclusions: Exercise improved PD symptoms, especially in RCTs with lower risk of bias or with ≥150 min/day moderate intensity aerobic exercise interventions. Findings are clinically useful but more RCTs for clinically diagnosed PD women are needed for firmer conclusions. © 2021 Elsevier B.V. | en |
dc.language.iso | en | en |
dc.source | Journal of Affective Disorders | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118554874&doi=10.1016%2fj.jad.2021.10.124&partnerID=40&md5=16c905c91b5cf965f3ce82b01c83f94b | |
dc.subject | adult | en |
dc.subject | aerobic exercise | en |
dc.subject | antidepressant activity | en |
dc.subject | clinical outcome | en |
dc.subject | disease severity | en |
dc.subject | exercise intensity | en |
dc.subject | female | en |
dc.subject | health service | en |
dc.subject | human | en |
dc.subject | meta analysis | en |
dc.subject | muscle stretching | en |
dc.subject | perinatal depression | en |
dc.subject | physical activity | en |
dc.subject | randomized controlled trial (topic) | en |
dc.subject | Review | en |
dc.subject | sensitivity analysis | en |
dc.subject | systematic review | en |
dc.subject | depression | en |
dc.subject | exercise | en |
dc.subject | pregnancy | en |
dc.subject | antidepressant agent | en |
dc.subject | Antidepressive Agents | en |
dc.subject | Depression | en |
dc.subject | Exercise | en |
dc.subject | Female | en |
dc.subject | Health Services | en |
dc.subject | Humans | en |
dc.subject | Pregnancy | en |
dc.subject | Randomized Controlled Trials as Topic | en |
dc.subject | Elsevier B.V. | en |
dc.title | Exercise for perinatal depressive symptoms: A systematic review and meta-analysis of randomized controlled trials in perinatal health services | en |
dc.type | other | en |