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Administration of an oral hydration solution prevents electrolyte and fluid disturbances and reduces readmissions in patients with a diverting ileostomy after colorectal surgery: A prospective, randomized, controlled trial
dc.creator | Migdanis A., Koukoulis G., Mamaloudis I., Baloyiannis I., Migdanis I., Kanaki M., Malissiova E., Tzovaras G. | en |
dc.date.accessioned | 2023-01-31T08:59:59Z | |
dc.date.available | 2023-01-31T08:59:59Z | |
dc.date.issued | 2018 | |
dc.identifier | 10.1097/DCR.0000000000001082 | |
dc.identifier.issn | 00123706 | |
dc.identifier.uri | http://hdl.handle.net/11615/76630 | |
dc.description.abstract | BACKGROUND: Patients with a newly formed ileostomy often develop electrolyte abnormalities and dehydration. OBJECTIVE: The study assessed the prophylactic effect of an isotonic hydration solution on dehydration and electrolyte abnormalities in patients with a newly formed ileostomy. DESIGN: This was a prospective, randomized, controlled trial (NCT02036346). SETTINGS: The study was conducted at a single surgical unit of a public university hospital. PATIENTS: Patients scheduled for elective rectosigmoid resection were considered for study inclusion. INTERVENTION: Patients in whom a diverting ileostomy was created were randomly assigned to the intervention group (n = 39), which received an oral isotonic glucosesodium hydration solution for 40 days postdischarge and the control group (n = 41) which did not receive an intervention. The 2 groups were compared with a group of patients who underwent rectosigmoid resection without diverting ileostomy (n = 37). MAIN OUTCOME MEASURES: Serum electrolyte and renal function markers were assessed preoperatively and at 20 and 40 days postdischarge. RESULTS: At 20 days postdischarge, the serum sodium of the control group appeared lower than the serum sodium of the intervention group and the nonileostomy group (p = 0.007). At the same time point, urea and creatinine levels of the control group were higher than the urea and creatinine levels of the other 2 groups (p = 0.01 and p = 0.02). At 40 days postdischarge, mean sodium and renal function markers improved in the control group, but sodium and creatinine continued to differ in comparison with the intervention and nonileostomy groups (p = 0.01 and p = 0.04). The readmission rate for?uid and electrolyte abnormalities was higher in the control group (24%) than in the other 2 groups, where no rehospitalization for such a reason was required (p = 0.001). LIMITATIONS: The study was limited by its single-center design. CONCLUSION: An oral isotonic drink postdischarge can have a prophylactic effect on patients with a newly formed ileostomy, preventing readmission for fluid and electrolyte abnormalities. © 2018 Wolters Kluwer Health, Inc. All rights reserved. | en |
dc.language.iso | en | en |
dc.source | Diseases of the Colon and Rectum | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049253669&doi=10.1097%2fDCR.0000000000001082&partnerID=40&md5=e2b82376572bf1e9cca14efa6ce4315a | |
dc.subject | creatinine | en |
dc.subject | isotonic solution | en |
dc.subject | oral rehydration solution | en |
dc.subject | sodium | en |
dc.subject | urea | en |
dc.subject | oral rehydration solution | en |
dc.subject | sodium | en |
dc.subject | Article | en |
dc.subject | colorectal surgery | en |
dc.subject | controlled study | en |
dc.subject | creatinine blood level | en |
dc.subject | dehydration | en |
dc.subject | elective surgery | en |
dc.subject | electrolyte disturbance | en |
dc.subject | hospital discharge | en |
dc.subject | hospital readmission | en |
dc.subject | human | en |
dc.subject | hydration | en |
dc.subject | ileostomy | en |
dc.subject | kidney function | en |
dc.subject | preoperative evaluation | en |
dc.subject | prophylaxis | en |
dc.subject | prospective study | en |
dc.subject | randomized controlled trial | en |
dc.subject | sodium blood level | en |
dc.subject | university hospital | en |
dc.subject | urea blood level | en |
dc.subject | abdominal surgery | en |
dc.subject | aged | en |
dc.subject | blood | en |
dc.subject | colon resection | en |
dc.subject | dehydration | en |
dc.subject | female | en |
dc.subject | fluid therapy | en |
dc.subject | hospital readmission | en |
dc.subject | ileostomy | en |
dc.subject | male | en |
dc.subject | metabolic disorder | en |
dc.subject | middle aged | en |
dc.subject | postoperative care | en |
dc.subject | postoperative complication | en |
dc.subject | procedures | en |
dc.subject | rectum | en |
dc.subject | sigmoid | en |
dc.subject | statistics and numerical data | en |
dc.subject | surgery | en |
dc.subject | Aged | en |
dc.subject | Colectomy | en |
dc.subject | Colon, Sigmoid | en |
dc.subject | Dehydration | en |
dc.subject | Digestive System Surgical Procedures | en |
dc.subject | Female | en |
dc.subject | Fluid Therapy | en |
dc.subject | Humans | en |
dc.subject | Ileostomy | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Patient Readmission | en |
dc.subject | Postoperative Care | en |
dc.subject | Postoperative Complications | en |
dc.subject | Rectum | en |
dc.subject | Rehydration Solutions | en |
dc.subject | Sodium | en |
dc.subject | Water-Electrolyte Imbalance | en |
dc.subject | Lippincott Williams and Wilkins | en |
dc.title | Administration of an oral hydration solution prevents electrolyte and fluid disturbances and reduces readmissions in patients with a diverting ileostomy after colorectal surgery: A prospective, randomized, controlled trial | en |
dc.type | journalArticle | en |
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