Guidelines for the Management of Wet Age-Related Macular Degeneration: Recommendations from a Panel of Greek Experts
dc.creator | Androudi S., Dastiridou A., Pharmakakis N., Stefaniotou M., Kalogeropoulos C., Symeonidis C., Charonis A., Tsilimbaris M. | en |
dc.date.accessioned | 2023-01-31T07:31:38Z | |
dc.date.available | 2023-01-31T07:31:38Z | |
dc.date.issued | 2016 | |
dc.identifier | 10.1007/s12325-016-0332-7 | |
dc.identifier.issn | 0741238X | |
dc.identifier.uri | http://hdl.handle.net/11615/70585 | |
dc.description.abstract | Purpose: To propose guidelines for the management of patients with wet age-related macular degeneration (wAMD), taking into account the results of large multicenter studies and clinical experience of retina experts. Method: A team of retina experts developed a consensus paper after three consecutive meetings. The group was focused on guidelines to help clinical decision-making around the definition of successful treatment and the definition of non-response to therapy. Results: Parameters suggestive of a successful response to treatments included: any gain in best corrected visual acuity (BCVA) or vision loss that is less than 5–10 Early Treatment Diabetic Retinopathy Study (ETDRS) letters, reduction of central retinal thickness, partial or complete absorption of subretinal fluid (SRF), reduction of intraretinal fluid, reduction of pigment epithelial detachment or restoration of the anatomy of outer retinal layers. Non-response to current treatment was considered in the case of loss of BCVA greater than 10 ETDRS letters, increased retinal edema or increase of SRF as evidenced by optical coherence tomography or new bleeding in biomicroscopy. Conclusion: The introduction of anti-VEGF agents revolutionized the treatment of wAMD. Given the complexity of the disease, the emerging new agents and the difference of cases recruited in clinical trials compared to those appearing in every-day practice, it is essential to individualize treatment options taking into account the results of clinical trials. © 2016, The Author(s). | en |
dc.language.iso | en | en |
dc.source | Advances in Therapy | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84971354002&doi=10.1007%2fs12325-016-0332-7&partnerID=40&md5=e3476c9e270ae4fb70eb856ac5231731 | |
dc.subject | angiogenic factor | en |
dc.subject | ranibizumab | en |
dc.subject | angiogenesis inhibitor | en |
dc.subject | vasculotropin A | en |
dc.subject | age related macular degeneration | en |
dc.subject | anatomy | en |
dc.subject | biomicroscopy | en |
dc.subject | central retinal thickness | en |
dc.subject | central scotoma | en |
dc.subject | clinical decision making | en |
dc.subject | contrast sensitivity | en |
dc.subject | human | en |
dc.subject | ophthalmology | en |
dc.subject | optical coherence tomography | en |
dc.subject | practice guideline | en |
dc.subject | relapse | en |
dc.subject | retina detachment | en |
dc.subject | retina edema | en |
dc.subject | Review | en |
dc.subject | subretinal fluid | en |
dc.subject | treatment response | en |
dc.subject | visual acuity | en |
dc.subject | visual impairment | en |
dc.subject | wet age related macular degeneration | en |
dc.subject | aged | en |
dc.subject | antagonists and inhibitors | en |
dc.subject | disease course | en |
dc.subject | disease management | en |
dc.subject | Greece | en |
dc.subject | metabolism | en |
dc.subject | pathophysiology | en |
dc.subject | procedures | en |
dc.subject | wet macular degeneration | en |
dc.subject | Aged | en |
dc.subject | Angiogenesis Inhibitors | en |
dc.subject | Disease Management | en |
dc.subject | Disease Progression | en |
dc.subject | Greece | en |
dc.subject | Humans | en |
dc.subject | Practice Guidelines as Topic | en |
dc.subject | Tomography, Optical Coherence | en |
dc.subject | Vascular Endothelial Growth Factor A | en |
dc.subject | Wet Macular Degeneration | en |
dc.subject | Springer Healthcare | en |
dc.title | Guidelines for the Management of Wet Age-Related Macular Degeneration: Recommendations from a Panel of Greek Experts | en |
dc.type | other | en |
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