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Potential Role of the Alcohol and Smoking in the Squamous Cell Carcinoma of the Head And Neck: Review of the Current Literature and New Perspectives

dc.creatorZygogianni, A.en
dc.creatorKyrgias, G.en
dc.creatorMystakidou, K.en
dc.creatorAntypas, C.en
dc.creatorKouvaris, J.en
dc.creatorPapadimitriou, C.en
dc.creatorArmonis, V.en
dc.creatorAlkati, H.en
dc.creatorKouloulias, V.en
dc.date.accessioned2015-11-23T10:55:30Z
dc.date.available2015-11-23T10:55:30Z
dc.date.issued2011
dc.identifier.issn1513-7368
dc.identifier.urihttp://hdl.handle.net/11615/35046
dc.description.abstractAlcohol and tobacco are responsible for a very large proportion of chronic disease and some tumors in particular may be the result of interactions between the two risk factors. The present systematic literature review was conducted to judge combined effects of alcohol drinking and tobacco, as well as and genetic polymorphisms on alcohol-related cancer risk. We can conclude that the interaction of smoking and alcohol significantly increases the risk for aero-digestive cancers. Unfortunately, little is known about mechanisms and details of interaction with regard to disease outcomes, which is why particular questions must be targeted in future research efforts.en
dc.source.uri<Go to ISI>://WOS:000293172800001
dc.subjectAlcohol consumptionen
dc.subjecttobacco smokingen
dc.subjectcanceren
dc.subjecthead and necken
dc.subjectfactoren
dc.subjectinteractionsen
dc.subjectUPPER AERODIGESTIVE TRACTen
dc.subjectMETHYLENETETRAHYDROFOLATE REDUCTASEen
dc.subjectPOLYMORPHISMen
dc.subjectLARYNGEAL-CANCER RISKen
dc.subjectHUMAN-LIVER ALCOHOLen
dc.subjectS-TRANSFERASEen
dc.subjectM1en
dc.subjectGENETIC POLYMORPHISMSen
dc.subjectHUMAN-PAPILLOMAVIRUSen
dc.subjectORAL-CANCERen
dc.subjectCOLORECTAL-CANCERen
dc.subjectALDEHYDE DEHYDROGENASESen
dc.subjectOncologyen
dc.titlePotential Role of the Alcohol and Smoking in the Squamous Cell Carcinoma of the Head And Neck: Review of the Current Literature and New Perspectivesen
dc.typejournalArticleen


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