dc.creator | Petinaki, E. | en |
dc.creator | Kontos, F. | en |
dc.creator | Miriagou, V. | en |
dc.creator | Maniati, M. | en |
dc.creator | Hatzi, F. | en |
dc.creator | Maniatis, A. N. | en |
dc.date.accessioned | 2015-11-23T10:45:25Z | |
dc.date.available | 2015-11-23T10:45:25Z | |
dc.date.issued | 2001 | |
dc.identifier | 10.1016/S0924-8579(01)00454-X | |
dc.identifier.issn | 9248579 | |
dc.identifier.uri | http://hdl.handle.net/11615/32180 | |
dc.description.abstract | A sample of 450 consecutive, non-replicated coagulase-negative staphylococci (CoNS), collected from clinical specimens during the period 2000-2001 from the five major hospitals of Thessaly district (Central Greece) were investigated for resistance to methicillin. Most of the isolates had been collected in a sporadic fashion from the intensive care units and the surgical wards of the participating hospitals. The majority of the isolates (76%) were Staphylococcus epidermidis (50%), Staphylococcus haemolyticus (14.8%) and Staphylococcus hominis (11.1%). All 316 isolates (70%) were classified as resistant according to NCCLS breakpoints (MIC ≥ 0.5 mg/l); 268 (59.5%) of them were mecA-positive in a PCR-based assay. All isolates with MIC ≥ 8 mg/l carried the gene, while, only 23.8% of isolates with MIC, 0.5-4 mg/l were carriers. Only 9% of the mecA-positive isolates were found to be sensitive to various non-β-lactams, while 41.8% of the isolates were resistant to more than three antimicrobial groups apart from β-lactams. Molecular typing by PFGE showed apparent heterogeneity among isolates of each species and the absence of predominant clones. © 2001 Elsevier Science B.V. and the International Society of Chemotherapy. All rights reserved. | en |
dc.source.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-0035215982&partnerID=40&md5=e81f52dd1c8b7be72a2a06f36c4fe167 | |
dc.subject | Coagulase-negative staphylococci | en |
dc.subject | Methicillin-resistance | en |
dc.subject | beta lactam antibiotic | en |
dc.subject | clindamycin | en |
dc.subject | cotrimoxazole | en |
dc.subject | erythromycin | en |
dc.subject | fusidic acid | en |
dc.subject | gentamicin | en |
dc.subject | ofloxacin | en |
dc.subject | oxacillin | en |
dc.subject | penicillin G | en |
dc.subject | rifampicin | en |
dc.subject | tetracycline | en |
dc.subject | tobramycin | en |
dc.subject | vancomycin | en |
dc.subject | antibiotic resistance | en |
dc.subject | antibiotic sensitivity | en |
dc.subject | article | en |
dc.subject | bacterium isolate | en |
dc.subject | bacterium isolation | en |
dc.subject | coagulase negative Staphylococcus | en |
dc.subject | controlled study | en |
dc.subject | Greece | en |
dc.subject | hospital | en |
dc.subject | intensive care unit | en |
dc.subject | minimum inhibitory concentration | en |
dc.subject | nonhuman | en |
dc.subject | penicillin resistance | en |
dc.subject | phenotype | en |
dc.subject | polymerase chain reaction | en |
dc.subject | priority journal | en |
dc.subject | Staphylococcus epidermidis | en |
dc.subject | Staphylococcus haemolyticus | en |
dc.subject | Staphylococcus hominis | en |
dc.subject | surgical ward | en |
dc.subject | Coagulase | en |
dc.subject | Cross Infection | en |
dc.subject | Genotype | en |
dc.subject | Hospitals | en |
dc.subject | Humans | en |
dc.subject | Intensive Care Units | en |
dc.subject | Methicillin | en |
dc.subject | Methicillin Resistance | en |
dc.subject | Microbial Sensitivity Tests | en |
dc.subject | Penicillins | en |
dc.subject | Staphylococcal Infections | en |
dc.subject | Staphylococcus | en |
dc.title | Survey of methicillin-resistant coagulase-negative staphylococci in the hospitals of central Greece | en |
dc.type | journalArticle | en |