dc.creator | Ntaios, G. | en |
dc.creator | Papavasileiou, V. | en |
dc.creator | Milionis, H. | en |
dc.creator | Makaritsis, K. | en |
dc.creator | Manios, E. | en |
dc.creator | Spengos, K. | en |
dc.creator | Michel, P. | en |
dc.creator | Vemmos, K. | en |
dc.date.accessioned | 2015-11-23T10:41:31Z | |
dc.date.available | 2015-11-23T10:41:31Z | |
dc.date.issued | 2015 | |
dc.identifier | 10.1161/strokeaha.114.007240 | |
dc.identifier.issn | 0039-2499 | |
dc.identifier.uri | http://hdl.handle.net/11615/31445 | |
dc.description.abstract | Background and Purpose-A new clinical construct termed embolic stroke of undetermined source (ESUS) was recently introduced, but no such population has been described yet. Our aim is to provide a detailed descriptive analysis of an ESUS population derived from a large prospective ischemic stroke registry using the proposed diagnostic criteria. Methods-The criteria proposed by the Cryptogenic Stroke/ESUS International Working Group were applied to the Athens Stroke Registry to identify all ESUS patients. ESUS was defined as a radiologically confirmed nonlacunar brain infarct in the absence of (a) extracranial or intracranial atherosclerosis causing >= 50% luminal stenosis in arteries supplying the ischemic area, (b) major-risk cardioembolic source, and (c) any other specific cause of stroke. Results-Among 2735 patients admitted between 1992 and 2011, 275 (10.0%) were classified as ESUS. In the majority of ESUS (74.2%), symptoms were maximal at onset. ESUS were of moderate severity (median National Institute Health Stroke Scale score, 5). The most prevalent risk factor was arterial hypertension (64.7%), and 50.9% of patients were dyslipidemic. Among potential causes of the ESUS, covert atrial fibrillation (AF) was the most prevalent: in 30 (10.9%) patients, AF was diagnosed during hospitalization for stroke recurrence, whereas in 50 (18.2%) patients AF was detected after repeated ECG monitoring during follow-up. Also, covert AF was strongly suggested in 38 patients (13.8%) but never recorded. Conclusions-About 10% of patients with first-ever ischemic stroke met criteria for ESUS; covert paroxysmal AF seems to be a frequent cause of ESUS. | en |
dc.source.uri | <Go to ISI>://WOS:000346735800043 | |
dc.subject | covert atrial fibrillation | en |
dc.subject | cryptogenic | en |
dc.subject | embolic stroke of undetermined | en |
dc.subject | cause | en |
dc.subject | embolism | en |
dc.subject | ESUS | en |
dc.subject | ACUTE ISCHEMIC-STROKE | en |
dc.subject | ATRIAL-FIBRILLATION | en |
dc.subject | RISK STRATIFICATION | en |
dc.subject | CRYPTOGENIC STROKE | en |
dc.subject | PREDICTING STROKE | en |
dc.subject | DIAGNOSIS | en |
dc.subject | SCALE | en |
dc.subject | Clinical Neurology | en |
dc.subject | Peripheral Vascular Disease | en |
dc.title | Embolic Strokes of Undetermined Source in the Athens Stroke Registry A Descriptive Analysis | en |
dc.type | journalArticle | en |