dc.creator | Manolakis, A. C. | en |
dc.creator | Kapsoritakis, A. N. | en |
dc.creator | Tsikouras, A. D. | en |
dc.creator | Tsiopoulos, F. D. | en |
dc.creator | Psychos, A. K. | en |
dc.creator | Potamianos, S. P. | en |
dc.date.accessioned | 2015-11-23T10:38:44Z | |
dc.date.available | 2015-11-23T10:38:44Z | |
dc.date.issued | 2008 | |
dc.identifier | 10.3748/wjg.14-4241 | |
dc.identifier.issn | 1007-9327 | |
dc.identifier.uri | http://hdl.handle.net/11615/30642 | |
dc.description.abstract | Hemobilia is a rare manifestation of hemophilia and is usually iatrogenic following liver biopsy. There are only few reports of spontaneous hemobilia in hemophilia patients. Cholangiocarcinoma is a well-established cause of hemobilia. We describe a case of a 70-year-old male, with known haemophilia B and a past history of papillotomy, who presented with classical symptoms of hemobilia. The initial diagnostic work-up failed to demonstrate a potential cause of bleeding other than the coagulopathy. Three months later, he was readmitted to our hospital with a second episode of hemobilia. During the second work-up, a cholangiocarcinoma was diagnosed both by imaging studies and by a significant elevation of cancer antigen 19-9. Although hemobilia could be attributed to hemophilia, especially in a patient with previous papillotomy, an underlying malignancy of the biliary tree should be suspected. (C) 2008 The WJG Press. All rights reserved. | en |
dc.source | World Journal of Gastroenterology | en |
dc.source.uri | <Go to ISI>://WOS:000257955300023 | |
dc.subject | hemobilia | en |
dc.subject | hemophilia | en |
dc.subject | cholangiocarcinoma | en |
dc.subject | cancer antigen 19-9 | en |
dc.subject | cholangiopancreatography | en |
dc.subject | TRANSJUGULAR LIVER-BIOPSY | en |
dc.subject | CHOLANGITIS | en |
dc.subject | Gastroenterology & Hepatology | en |
dc.title | Hemobilia as the initial manifestation of cholangiocarcinoma in a hemophilia B patient | en |
dc.type | journalArticle | en |