UGT1A1 promoter polymorphism as a predisposing factor of hyperbilirubinaemia in neonates with acute pyelonephritis

dc.creator	Fretzayas, A.	en
dc.creator	Kitsiou, S.	en
dc.creator	Tsezou, A.	en
dc.creator	Alexaki, A.	en
dc.creator	Nicolaidou, P.	en
dc.date.accessioned	2015-11-23T10:26:47Z
dc.date.available	2015-11-23T10:26:47Z
dc.date.issued	2006
dc.identifier	10.1080/00365540500494087
dc.identifier.issn	0036-5548
dc.identifier.uri	http://hdl.handle.net/11615/27575
dc.description.abstract	We describe 4 jaundiced neonates with acute pyelonephritis of whom family history was positive for or pointed to Gilbert's syndrome (GS). Uridine diphosphate glucuronosyltransferase 1A1 (UGT-1A1), ( TA) 7 polymorphism, associated with GS was found in these neonates. We suggest that extended ( TA) 7 promoter, acting as a predisposing factor, contributes substantially to hyperbilirubinaemia seen in a number of neonates with urinary tract infections (UTIs).	en
dc.source	Scandinavian Journal of Infectious Diseases	en
dc.source.uri	<Go to ISI>://WOS:000238562300023
dc.subject	URINARY-TRACT INFECTIONS	en
dc.subject	BACTERIAL INFECTION	en
dc.subject	GILBERTS-SYNDROME	en
dc.subject	FEBRILE INFANTS	en
dc.subject	BILIRUBIN LEVEL	en
dc.subject	JAUNDICE	en
dc.subject	EXPRESSION	en
dc.subject	NEWBORN	en
dc.subject	LIVER	en
dc.subject	GENE	en
dc.subject	Infectious Diseases	en
dc.title	UGT1A1 promoter polymorphism as a predisposing factor of hyperbilirubinaemia in neonates with acute pyelonephritis	en
dc.type	journalArticle	en

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