Όλο το DSpace

Πλοήγηση ανά Θέμα "Sepsis"

Αποτελέσματα 1-20 από 20

    • -572 G/C single nucleotide polymorphism of interleukin-6 and sepsis predisposition in chronic renal disease 

      Panayides A., Ioakeimidou A., Karamouzos V., Antonakos N., Koutelidakis I., Giannikopoulos G., Makaritsis K., Voloudakis N., Toutouzas K., Rovina N., Bristianou M., Damoraki G., Routsi C., Giamarellos-Bourboulis E.J. (2015)
      Single nucleotide polymorphisms (SNPs) of interleukin (IL)-6 are associated with the development of chronic renal disease (CRD). Their impact for sepsis in the field of CRD was investigated. One control cohort of 115 ...

    • Angiopoietin-2 associations with the underlying infection and sepsis severity 

      Lymperopoulou, K.; Velissaris, D.; Kotsaki, A.; Antypa, E.; Georgiadou, S.; Tsaganos, T.; Koulenti, D.; Paggalou, E.; Damoraki, G.; Karagiannidis, N.; Orfanos, S. E. (2015)
      Angiopoietin-2 (Ang-2) is an important mediator in sepsis. We have previously shown that endotoxemia levels are related to the underlying infection and affect septic patients' outcome. Based on this background we now ...

    • Antibiotic use and the prevention and management of infectious complications in stone disease 

      Wollin D.A., Joyce A.D., Gupta M., Wong M.Y.C., Laguna P., Gravas S., Gutierrez J., Cormio L., Wang K., Preminger G.M. (2017)
      The importance of assessing perioperative urine/stone cultures and providing appropriate antibiotic prophylaxis prior to shock wave lithotripsy (SWL) or endoscopic intervention cannot be minimized. Urinary tract infection ...

    • Bloodstream infections and sepsis in Greece: Over-time change of epidemiology and impact of de-escalation on final outcome 

      Koupetori, M.; Retsas, T.; Antonakos, N.; Vlachogiannis, G.; Perdios, I.; Nathanail, C.; Makaritsis, K.; Papadopoulos, A.; Sinapidis, D.; Giamarellos-Bourboulis, E. J.; Pneumatikos, I.; Gogos, C.; Armaganidis, A.; Paramythiotou, E. (2014)
      Background: Choice of empirically prescribed antimicrobials for sepsis management depends on epidemiological factors. The epidemiology of sepsis in Greece was studied in two large-periods.Methods: Sepsis due to bloodstream ...

    • Diabetes on sepsis outcomes in non-ICU patients: A cohort study and review of the literature 

      Akinosoglou K., Kapsokosta G., Mouktaroudi M., Rovina N., Kaldis V., Stefos A., Kontogiorgi M., Giamarellos-Bourboulis E., Gogos C., Hellenic Sepsis Study Group (2021)
      Aims: We sought to determine whether primary outcomes differ between non-ICU septic patients with and without type 2 diabetes (T2D). Methods: This study utilized the Hellenic Sepsis Study Group Registry, collecting nationwide ...

    • The effect of homocysteine on the clinical outcomes of ventilated patients with severe sepsis 

      Tsantes, A.; Tsangaris, I.; Nikolopoulos, G.; Bagos, P.; Kopterides, P.; Antonakos, G.; Dimopoulou, I.; Vrioni, G.; Kapsimali, V.; Dima, K.; Armaganidis, A.; Travlou, A. (2010)
      Background. There is considerable evidence that elevated plasma homocysteine levels are associated with a prothrombotic milieu, whereas activation of the coagulation cascade is an important component of the pathogenesis ...

    • Genetic polymorphisms of innate and adaptive immunity as predictors of outcome in critically ill patients 

      Kompoti, M.; Michopoulos, A.; Michalia, M.; Clouva-Molyvdas, P. M.; Germenis, A. E.; Speletas, M. (2015)
      Sepsis and septic shock frequently cause the admission or complicate the clinical course of critically ill patients admitted in the intensive care units (ICU). Genetic variations disrupting the immune sensing of infectious ...

    • Geographical variation in therapy for bloodstream infections due to multidrug-resistant Enterobacteriaceae: a post-hoc analysis of the INCREMENT study 

      Harris P.N.A., Pezzani M.D., Gutiérrez-Gutiérrez B., Viale P., Hsueh P.-R., Ruiz-Garbajosa P., Venditti M., Tumbarello M., Navarro-Francisco C., Calbo E., Akova M., Giamarellou H., Oliver A., Almirante B., Gasch O., Martínez-Martínez L., Schwaber M.J., Daikos G., Pitout J., Peña C., Hernández-Torres A., Doi Y., Pérez F., Tuon F.F., Tacconelli E., Carmeli Y., Bonomo R.A., Pascual Á., Paterson D.L., Rodríguez-Baño J., del Toro M.D., Gálvez J., Falcone M., Russo A., Karaiskos I., Trecarichi E.M., Losito A.R., García-Vázquez E., Gómez J., Roilides E., Iosifidis E., Pournaras S., Prim N., Navarro F., Mirelis B., Origüen J., Juan R.S., Fernández-Ruiz M., Almela M., de la Calle C., Martínez J.A., Morata L., Larrosa N., Puig-Asensio M., Bou G., Molina J., González V., Bermejo J., Rucci V., de Gopegui E.R., Marinescu C.I., Fariñas M.C., Cano M.E., Gozalo M., Paño-Pardo J.R., Mora-Rillo M., Gómez-Zorrilla S., Tubau F., Tsakris A., Zarkotou O., Antoniadou A., Poulakou G., Souli M., Lowman W., Virmani D., Torre-Cisneros J., Machuca I., Gracia-Ahufinger I., Azap Ö.K., Helvaci Ö., Sahin A.O., Cantón R., Pintado V., Bartoletti M., Giannella M., Peter S., Hamprecht A., Badia C., Xercavins M., Fontanals D., Jové E., ESGBIS/REIPI/INCREMENT Group (2017)
      We describe regional differences in therapy for bloodstream infection (BSI) caused by extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) or carbapenemase-producing Enterobacteriaceae (CPE). Patients (n = ...

    • Increasing stress volume vs. increasing tissue perfusion in septic patients 

      Chalkias A. (2022)
      [No abstract available]

    • Intraoperative initiation of a modified ARDSNet protocol increases survival of septic patients with severe acute respiratory distress syndrome 

      Chalkias A., Xanthos T., Papageorgiou E., Anania A., Beloukas A., Pavlopoulos F. (2018)
      Purpose: To assess the intraoperative initiation and feasibility of a modified NIH-NHLBI ARDS Network Mechanical Ventilation Protocol (mARDSNet protocol) in septic patients with severe ARDS. Materials and methods: This ...

    • MACHINE LEARNING to DEVELOP A MODEL THAT PREDICTS EARLY IMPENDING SEPSIS in NEUROSURGICAL PATIENTS 

      Vlachos E., Salapatas Gkinis A., Papastergiou V., Tsitsipanis C., Giannakopoulos G. (2022)
      Sepsis is currently defined as a "life-threatening organ dysfunction caused by a dysregulated host response to infection". The early detection and prediction of sepsis is a challenging task, with significant potential gains ...

    • Open or Endovascular Repair of Aortoenteric Fistulas? A Multicentre Comparative Study 

      Kakkos, S. K.; Antoniadis, P. N.; Klonaris, C. N.; Papazoglou, K. O.; Giannoukas, A. D.; Matsagkas, M. I.; Kotsis, T.; Dervisis, K.; Gerasimidis, T.; Tsolakis, I. A.; Liapis, C. D. (2011)
      Objectives: To compare aortoenteric fistula (AEF) outcome after endovascular (EV-AEFR) or open repair (O-AEFR). Design: Multicentre retrospective comparative study. Materials/Methods: 25 patients with AEF (24 secondary, ...

    • Oxidative status in ICU patients with septic shock 

      Karapetsa, M.; Pitsika, M.; Goutzourelas, N.; Stagos, D.; Becker, A. T.; Zakynthinos, E. (2013)
      The aim of this pilot study was to investigate variability of oxidative stress during sepsis evolution. ICU patients with the diagnosis of septic shock were included. Thiobarbituric-acid reactive substances, total antioxidant ...

    • Progression into sepsis: An individualized process varying by the interaction of comorbidities with the underlying infection 

      Sinapidis D., Kosmas V., Vittoros V., Koutelidakis I.M., Pantazi A., Stefos A., Katsaros K.E., Akinosoglou K., Bristianou M., Toutouzas K., Chrisofos M., Giamarellos-Bourboulis E.J. (2018)
      Background: Development of sepsis is a process with significant variation among individuals. The precise elements of this variation need to be defined. This study was designed to define the way in which comorbidities ...

    • Role of Oxidative Stress and Mitochondrial Dysfunction in Sepsis and Potential Therapies 

      Mantzarlis K., Tsolaki V., Zakynthinos E. (2017)
      Sepsis is one of the most important causes of death in intensive care units. Despite the fact that sepsis pathogenesis remains obscure, there is increasing evidence that oxidants and antioxidants play a key role. The ...

    • Secondary bacterial infections are a leading factor triggering New Onset Atrial Fibrillation in intubated ICU Covid-19 ARDS patients 

      Zakynthinos G.E., Tsolaki V., Karavidas N., Vazgiourakis V., Dimeas G., Mantzarlis K., Vavougios G., Makris D. (2022)
      Background: Cardiac arrhythmias, mainly atrial fibrillation (AF), is frequently reported in COVID-19 patients, more often in Intensive Care Unit (ICU) patients, yet causality has not been virtually explored. Moreover, ...

    • Sepsis-Induced Cardiomyopathy: Oxidative Implications in the Initiation and Resolution of the Damage 

      Tsolaki V., Makris D., Mantzarlis K., Zakynthinos E. (2017)
      Cardiac dysfunction may complicate the course of severe sepsis and septic shock with significant implications for patient's survival. The basic pathophysiologic mechanisms leading to septic cardiomyopathy have not been ...

    • Statins in bacteremia, sepsis and pneumonia: Have we found the holy grail? 

      Stamatogiannis, N.; Makris, D.; Zakynthinos, E. (2009)
      Statins, beyond their lipid lowering properties, have pleiotropic properties that may modulate the inflammatory cascade and potentially could be useful in the management of inflammatory conditions such as bacteremia and ...

    • Toll-like receptors and their role in renal pathologies 

      Eleftheriadis, T.; Pissas, G.; Liakopoulos, V.; Stefanidis, I.; Lawson, B. R. (2012)
      Toll-like receptors (TLRs) are the first identified and best studied family of pattern recognition receptors. Expressed in immunocytes, TLRs initiate innate immune responses and concurrently shape the subsequent adaptive ...

    • Validation of the new Sepsis-3 definitions: proposal for improvement in early risk identification 

      Giamarellos-Bourboulis E.J., Tsaganos T., Tsangaris I., Lada M., Routsi C., Sinapidis D., Koupetori M., Bristianou M., Adamis G., Mandragos K., Dalekos G.N., Kritselis I., Giannikopoulos G., Koutelidakis I., Pavlaki M., Antoniadou E., Vlachogiannis G., Koulouras V., Prekates A., Dimopoulos G., Koutsoukou A., Pnevmatikos I., Ioakeimidou A., Kotanidou A., Orfanos S.E., Armaganidis A., Gogos C., the Hellenic Sepsis Study Group (2017)
      Objectives Sepsis-3 definitions generated controversies regarding their general applicability. The Sepsis-3 Task Force outlined the need for validation with emphasis on the quick Sequential Organ Failure Assessment (qSOFA) ...