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    • Anti-SLA/LP alone or in combination with anti-Ro52 and fine specificity of anti-Ro52 antibodies in patients with autoimmune hepatitis 

      Zachou, K.; Gampeta, S.; Gatselis, N. K.; Oikonomou, K.; Goulis, J.; Manoussakis, M. N.; Renaudineau, Y.; Bogdanos, D. P.; Dalekos, G. N. (2015)
      Background & AimsAntibodies (Abs) to soluble liver antigen/liver pancreas (anti-SLA/LP) are considered markers of worse prognosis and outcome in patients with autoimmune hepatitis (AIH) although this assumption has recently ...

    • Helicobacter pylori and autoimmune disease: Cause or bystander 

      Smyk, D. S.; Koutsoumpas, A. L.; Mytilinaiou, M. G.; Rigopoulou, E. I.; Sakkas, L. I.; Bogdanos, D. P. (2014)
      Helicobacter pylori (H. pylori) is the main cause of chronic gastritis and a major risk factor for gastric cancer. This pathogen has also been considered a potential trigger of gastric autoimmunity, and in particular of ...

    • IgA anti-b2GPI antibodies in patients with autoimmune liver diseases 

      Gabeta, S.; Norman, G. L.; Gatselis, N.; Liaskos, C.; Papamichalis, P. A.; Garagounis, A.; Zachou, K.; Rigopoulou, E. I.; Dalekos, G. N. (2008)
      Introduction Recently, we reported a high prevalence of immunoglobulin G and/or immunoglobulin M anticardiolipin antibodies (aCL) in patients with autoimmune liver diseases, namely, autoimmune hepatitis (AIH), primary ...

    • Low Serum Hepcidin in Patients with Autoimmune Liver Diseases 

      Lyberopoulou, A.; Chachami, G.; Gatselis, N. K.; Kyratzopoulou, E.; Saitis, A.; Gabeta, S.; Eliades, P.; Paraskeva, E.; Zachou, K.; Koukoulis, G. K.; Mamalaki, A.; Dalekos, G. N.; Simos, G. (2015)
      Hepcidin, a liver hormone, is important for both innate immunity and iron metabolism regulation. As dysfunction of the hepcidin pathway may contribute to liver pathology, we analysed liver hepcidin mRNA and serum hepcidin ...

    • A novel mutation of the hGR gene causing Chrousos syndrome 

      Nicolaides, N. C.; Geer, E. B.; Vlachakis, D.; Roberts, M. L.; Psarra, A. M. G.; Moutsatsou, P.; Sertedaki, A.; Kossida, S.; Charmandari, E. (2015)
      Background Natural mutations in the human glucocorticoid receptor (hGR, NR3C1) gene cause Chrousos syndrome, a rare condition characterized by generalized, partial, target-tissue insensitivity to glucocorticoids. Objective ...

    • Twin studies in autoimmune disease: Genetics, gender and environment 

      Bogdanos, D. P.; Smyk, D. S.; Rigopoulou, E. I.; Mytilinaiou, M. G.; Heneghan, M. A.; Selmi, C.; Gershwin, M. E. (2012)
      Twin studies are powerful tools to discriminate whether a complex disease is due to genetic or environmental factors. High concordance rates among monozygotic (MZ) twins support genetic factors being predominantly involved, ...