Πλοήγηση ανά Συγγραφέα "Mitroulis, I."
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Endothelin-1 Signaling Promotes Fibrosis In Vitro in a Bronchopulmonary Dysplasia Model by Activating the Extrinsic Coagulation Cascade
Kambas, K.; Chrysanthopoulou, A.; Kourtzelis, I.; Skordala, M.; Mitroulis, I.; Rafail, S.; Vradelis, S.; Sigalas, I.; Wu, Y. Q.; Speletas, M.; Kolios, G.; Ritis, K. (2011)Neonatal respiratory distress syndrome can progress to bronchopulmonary dysplasia (BPD), a serious pulmonary fibrotic disorder. Given the involvement of the extrinsic coagulation cascade in animal models of lung fibrosis, ... -
Fast and reliable mutation detection of the complete exon 11-15 JAK2 coding region using non-isotopic RNase cleavage assay (NIRCA)
Kambas, K.; Mitroulis, I.; Kourtzelis, I.; Chrysanthopoulou, A.; Speletas, M.; Ritis, K. (2009)The screening for JAK2 V617F mutation in patients with polycythemia vera, essential thrombocythemia, and idiopathic myelofibrosis offers crucial information for the final diagnosis of these disorders. Recently, several ... -
Genetic analysis of C5a receptors in neutrophils from patients with familial Mediterranean fever
Apostolidou, E.; Kambas, K.; Chrysanthopoulou, A.; Kourtzelis, I.; Speletas, M.; Ritis, K.; Mitroulis, I. (2012)Familial Mediterranean fever (FMF) is an autoinflammatory disease, characterized by MEFV gene mutations and self-limited recurrent episodes of fever and localized serositis. Complement system is a key regulator of the ... -
In vivo induction of the autophagic machinery in human bone marrow cells during Leishmania donovani complex infection
Mitroulis, I.; Kourtzelis, I.; Papadopoulos, V. P.; Mimidis, K.; Speletas, M.; Ritis, K. (2009)Autophagy is a homeostatic process promoting cell survival in periods of stress. The induction of the autophagic machinery has also been implicated in both innate and adaptive immunity. Leishmania donovani, which is the ... -
Regulation of the autophagic machinery in human neutrophils
Mitroulis, I.; Kourtzelis, I.; Kambas, K.; Rafail, S.; Chrysanthopoulou, A.; Speletas, M.; Ritis, K. (2010)The induction of the autophagy machinery, a process for the catabolism of cytosolic proteins and organelles, constitutes a crucial mechanism in innate immunity. However, the involvement of autophagy in human neutrophils ... -
TLR single nucleotide polymorphisms (SNPs) distribution among familial mediterranean fever (FMF) patients and normal individuals
Speletas, M.; Kalala, F.; Papadopoulos, V. P.; Merentiti, V.; Mitroulis, I.; Ritis, K.; Germenis, A. E. (2009) -
TLR2 and TLR4 polymorphisms in familial Mediterranean fever
Speletas, M.; Kalala, F.; Mitroulis, I.; Papadopoulos, V.; Merentiti, V.; Germenis, A. E.; Ritis, K. (2009)It has been suggested that MEVF mutations offer advantage against infections, including tuberculosis. Bearing in mind the central role of TLR-2 and TLR-4 in the recognition of pathogens, we conducted this study to examine ...