• Antithrombotic treatment in patients with stroke and supracardiac atherosclerosis 

      Sagris D., Georgiopoulos G., Leventis I., Pateras K., Pearce L.A., Korompoki E., Makaritsis K., Vemmos K., Milionis H., Ntaios G. (2020)
      Objective To compare the efficacy and safety of oral anticoagulants vs antiplatelets in patients with stroke and atherosclerotic plaques in the aortic arch or cervical or intracranial arteries, collectively described as ...
    • Aortic Arch Atherosclerosis in Patients With Embolic Stroke of Undetermined Source: An Exploratory Analysis of the NAVIGATE ESUS Trial 

      Ntaios G., Pearce L.A., Meseguer E., Endres M., Amarenco P., Ozturk S., Lang W., Bornstein N.M., Molina C.A., Pagola J., Mundl H., Berkowitz S.D., Liu Y.Y., Sen S., Connolly S.J., Hart R.G. (2019)
      Background and Purpose- Aortic arch atherosclerosis (AAA) is a possible source of embolism in patients with embolic stroke of undetermined source. Previous studies reported high rates of embolic events in patients with ...
    • Arginase type I as a marker of coronary heart disease in hemodialysis patients 

      Eleftheriadis, T.; Liakopoulos, V.; Antoniadi, G.; Stefanidis, I.; Galaktidou, G. (2011)
      Cardiovascular disease, and mainly coronary heart disease (CHD), is the leading cause of death in hemodialysis (HD) patients. Non-traditional risk factors may play an important role in this population. Arginase is known ...
    • Canine hyperlipidaemia 

      Xenoulis P.G., Steiner J.M. (2015)
      Hyperlipidaemia refers to an increased concentration of lipids in the blood. Hyperlipidaemia is common in dogs and has recently emerged as an important clinical condition that requires a systematic diagnostic approach and ...
    • Carotid Bifurcation Geometry and Atherosclerosis 

      Spanos K., Petrocheilou G., Karathanos C., Labropoulos N., Mikhailidis D., Giannoukas A. (2017)
      Hemodynamic changes occurring at the initial segments of the arterial bifurcations appear to play an important role in the development of atherosclerotic plaque. Therefore, arterial geometry might be a potential marker for ...
    • Depression and atherosclerosis 

      Saleptsis, V. G.; Labropoulos, N.; Halaris, A.; Angelopoulos, N. V.; Giannoukas, A. D. (2011)
      The aim of this paper was to examine the interaction between depression and atherosclerosis through a systematic review. A Medline search was performed from 1966 through 2009 using relevant terms such as depression, ...
    • Effects of obstructive sleep apnea severity on serum lipid levels in Greek children with snoring 

      Alexopoulos, E. I.; Gletsou, E.; Kostadima, E.; Kaditis, D.; Zakynthinos, E.; Gourgoulianis, K.; Kaditis, A. (2011)
      Although obstructive sleep apnea (OSA) is related to dyslipidemia in adults, limited data are available regarding its effects on serum lipids during childhood. Aim of this study was to assess the potential relationships ...
    • Erosive hand osteoarthritis is associated with subclinical atherosclerosis and endothelial dysfunction 

      Koutroumpas, A.; Giannoukas, A.; Zintzaras, E.; Exarchou, E.; Baliakos, A.; Makaritsis, K.; Sakkas, L. I. (2013)
      Chronic inflammatory disorders have been associated with accelerated atherosclerosis and increased cardiovascular (CV) risk. Recent evidence suggests that erosive hand osteoarthritis (EOA) has considerable inflammation; ...
    • Evidence of deregulated cholesterol efflux in abdominal aortic aneurysm 

      Mourmoura E., Vasilaki A., Giannoukas A., Michalodimitrakis E., Pavlidis P., Tsezou A. (2016)
      Previous studies indicated that lipids may be associated with abdominal aortic aneurysm (AAA); however the molecular mechanism involved is unclear. Our study aimed to investigate the expression pattern of cholesterol efflux ...
    • Glycosaminoglycans as Key Molecules in Atherosclerosis: The Role of Versican and Hyaluronan 

      Karangelis, D. E.; Kanakis, I.; Asimakopoulou, A. P.; Karousou, E.; Passi, A.; Theocharis, A. D.; Triposkiadis, F.; Tsilimingas, N. B.; Karamanos, N. K. (2010)
      Cardiovascular disease is the largest cause of death in Western societies and it primarily results from atherosclerosis of large and medium-sized vessels. Atherosclerosis leads to myocardial infarction, when it occurs in ...
    • Histology and immunohistochemistry of radial arteries are suggestive of an interaction between calcification and early atherosclerotic lesions in chronic kidney disease 

      Lysitska A., Galanis N., Skandalos I., Nikolaidou C., Briza S., Fylaktou A., Lioulios G., Mitsoglou Z., Papadopoulou D., Antoniadis N., Papagianni A., Stangou M. (2021)
      Background and Objectives: recent studies suggest an implication of immune mechanisms in atherosclerotic disease. In this paper, the interaction between inflammation, calcification, and atherosclerosis on the vessel walls ...
    • IL-1 cytokines in cardiovascular disease: Diagnostic, prognostic and therapeutic implications 

      Apostolakis, S.; Vogiatzi, K.; Krambovitis, E.; Spandidos, D. A. (2008)
      Interleukins (ILs) are key mediators in the chronic vascular inflammatory response underlying several aspects of cardiovascular disease. Due to their powerful pro-inflammatory potential, and the fact that they are highly ...
    • Immunity, Vascular Aging and Stroke 

      Louka A.-M., Sagris D., Ntaios G. (2022)
      Stroke is one of the most devastating manifestations of cardiovascular disease. Growing age, arterial hypertension, and atherosclerosis are identified as independent risk factors for stroke, primarily due to structural and ...
    • Lipid metabolism and osteoarthritis: Lessons from atherosclerosis 

      Gkretsi, V.; Simopoulou, T.; Tsezou, A. (2011)
      Osteoarthritis (OA) is an age-related degenerative disease comprising the main reason of handicap in the Western world. Interestingly, to date, there are neither available biomarkers for early diagnosis of the disease nor ...
    • Lipoprotein(a) is associated with large artery atherosclerosis stroke aetiology and stroke recurrence among patients below the age of 60 years: Results from the BIOSIGNAL study 

      Arnold M., Schweizer J., Nakas C.T., Schütz V., Westphal L.P., Inauen C., Pokorny T., Luft A., Leichtle A., Arnold M., Bicvic A., Fischer U., De Marchis G.M., Bonati L.H., Müller M.D., Kahles T., Nedeltchev K., Cereda C.W., Kägi G., Bustamante A., Montaner J., Ntaios G., Foerch C., Spanaus K., Von Eckardstein A., Katan M. (2021)
      Aims: Lipoprotein(a) [Lp(a)] is a recognized causal risk factor for atherosclerotic cardiovascular disease but its role for acute ischaemic stroke (AIS) is controversial. In this study, we evaluated the association of Lp(a) ...
    • Lipoproteins and atherosclerosis 

      Kotsovassilis, C.; Bei, T. A. (2003)
      The lipoproteins constitute valuable clinical diagnostic tools. This review will highlight the key clinical diagnostic aspects of the lipoprotein system at the phenotypic level; with the main focus on the following topics: ...
    • Loss of heterozygosity in DNA mismatch repair genes in human atherosclerotic plaques 

      Flouris, G. A.; Arvanitis, D. A.; Parissis, J. T.; Arvanitis, D. L.; Spandidos, D. A. (2001)
      To detect the incidence of loss of heterozygosity (LOH) in DNA mismatch repair genes (MMR) occurring in atherosclerosis, fifty human autopsy cases of atherosclerosis were examined for LOH using 19 microsatellite markers, ...
    • Mechanistic insights on the effect of crocin, an active ingredient of saffron, on atherosclerosis in apolipoprotein E knockout mice 

      Makaritsis K.P., Kotidis C., Papacharalampous K., Kouvaras E., Poulakida E., Tarantilis P., Asprodini E., Ntaios G., Koukoulis G.K., Dalekos G.N., Ioannou M. (2022)
      Background We investigated the effect of crocin treatment on atherosclerosis and serum lipids in apolipoprotein E knockout (ApoE-/-) mice, focusing on the expression of endothelial nitric oxide synthase (eNOS) and ...
    • Nocturnal change of circulating intercellular adhesion molecule 1 levels in children with snoring 

      Kaditis, A. G.; Alexopoulos, E. I.; Kalampouka, E.; Hatzi, F.; Karadonta, I.; Kyropoulos, T.; Kaditis, D. G.; Gourgoulianis, K.; Syrogiannopoulos, G. A. (2007)
      Hypoxia promotes adherence of leukocytes to endothelial cells by inducing expression of adhesion molecules like intercellular adhesion molecule 1 (ICAM-1). Increased serum levels of circulating ICAM-1 (cICAM-1) have been ...
    • Periodontitis and carotid atheroma: is there a causal relationship? 

      Tzorbatzoglou, I. D.; Sfyroeras, G. S.; Giannoukas, A. D. (2010)
      Periodontal diseases are highly prevalent in the population. Several studies implicated that chronic periodontitis may affect the arterial wall inducing subclinical atherosclerosis by triggering a systemic inflammatory ...