• Flash proton radiotherapy spares normal epithelial and mesenchymal tissues while preserving sarcoma response 

      Velalopoulou A., Karagounis I.V., Cramer G.M., Kim M.M., Skoufos G., Goia D., Hagan S., Verginadis I.I., Shoniyozov K., Chiango J., Cerullo M., Varner K., Yao L., Qin L., Hatzigeorgiou A.G., Minn A.J., Putt M., Lanza M., Assenmacher C.-A., Radaelli E., Huck J., Diffenderfer E., Dong L., Metz J., Koumenis C., Cengel K.A., Maity A., Busch T.M. (2021)
      In studies of electron and proton radiotherapy, ultrahigh dose rates of FLASH radiotherapy appear to produce fewer toxicities than standard dose rates while maintaining local tumor control. FLASHproton radiotherapy (F-PRT) ...
    • Intraoperative radiation therapy (IORT) in head and neck cancer: A systematic review 

      Kyrgias G., Hajiioannou J., Tolia M., Kouloulias V., Lachanas V., Skoulakis C., Skarlatos I., Rapidis A., Bizakis I. (2016)
      Background: Multimodality therapy constitutes the standard treatment of advanced and recurrent head and neck cancer. Since locoregional recurrence comprises a major obstacle in attaining cure, the role of intraoperative ...
    • Is locally advanced head-neck cancer one more candidate for accelerated hypofractionation? 

      KOUKOURAKIS I.M., ZYGOGIANNI A., KOULOULIAS V., KYRGIAS G., PANTELIADOU M., NANOS C., ABATZOGLOU I., KOUKOURAKIS M.I. (2021)
      Background/Aim: Hypofractionated accelerated radiotherapy (HypoAR) is widely applied for the treatment of early laryngeal cancer. Its role in locally advanced head-neck cancer (LA-HNC) is unexplored. Patients and Methods: ...
    • Late results of a randomized trial on the role of mild hypofractionated radiotherapy for the treatment of localized prostate cancer 

      Alexidis P., Karatzoglou S., Dragoumis D., Drevelegas K., Tzitzikas I., Hatzimouratidis K., Chrisogonidis I., Ioannidis A., Katsios I.N., Zarogoulidis P., Sapalidis K., Koulouris C., Michalopoulos N., Giannakidis D., Aidoni Z., Fyntanidou V., Amaniti A., Boniou K., Kesisoglou I., Vagionas A., Romanidis K., Oikonomou P., Goganau A.M., Petanidis S., Maragouli E., Kosmidis C. (2020)
      Background: Prostate cancer is considered to be highly sensitive to changes in radiation therapy dose per fraction, specifically to hypofractionation. An increase in the fractionation dose could cause a higher increase to ...
    • Oligometastasis and local ablation in the era of systemic targeted and immunotherapy 

      Mazzola R., Jereczek-Fossa B.A., Franceschini D., Tubin S., Filippi A.R., Tolia M., Lancia A., Minniti G., Corradini S., Arcangeli S., Scorsetti M., Alongi F. (2020)
      Background: During these last years, new agents have dramatically improved the survival of the metastatic patients. Oligometastases represent a continuous field of interest in which the integration of metastases-directed ...
    • Primary extramammary invasive Paget's vulvar disease: What is the standard, what are the challenges and what is the future for radiotherapy? 

      Tolia M., Tsoukalas N., Sofoudis C., Giaginis C., Spyropoulou D., Kardamakis D., Kouloulias V., Kyrgias G. (2016)
      Background: Primary invasive Extramammary Paget's vulvar disease is a rare tumor that is challenging to control. Wide surgical excision represents the standard treatment approach for Primary invasive Extramammary Paget's ...