Πλοήγηση ανά Θέμα "ovary cancer"
Αποτελέσματα 1-14 από 14
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Alterations of microRNAs in solid cancers and their prognostic value
(2010)MicroRNAs (miRNAs) are evolutionarily conserved, naturally abundant, small, regulatory non-coding RNAs that inhibit gene expression at the post-transcriptional level in a sequence-specific manner. Each miRNA represses the ... -
Anti-Ro52 antibody is highly prevalent and a marker of better prognosis in patients with ovarian cancer
(2021)Background and Aims: Anti-Ro52 antibody (Ab) reactivity is highly prevalent in autoimmune rheumatic diseases (ARDs), mainly Sjögren's syndrome (SjS) and systemic lupus erythematosus (SLE), but also in other inflammatory ... -
BRCA1 and BRCA2 germline testing in Cretan isolates reveals novel and strong founder effects
(2020)Germline BRCA1 and BRCA2 loss-of-function variants have been linked to increased breast and ovarian cancer risk, with more than 5,000 distinct pathogenic variants being reported worldwide. Among individuals of Greek descent, ... -
Endocrine resistance and epigenetic reprogramming in estrogen receptor positive breast cancer
(2021)Despite the enormous advances during the last three decades, breast cancer continues to be the most frequent type of cancer as well as one of the most frequent cancer-related causes of death in women. Therapeutic management ... -
Exercise, supportive group therapy, and mood profile of Greek cancer patients: intervention effect and related comparisons
(2018)Purpose: The purpose of this study was to examine the effect of exercise program and a group psychotherapy program on mood profile of Greek cancer patients as well as to make the necessary comparisons. Methods: The sample ... -
Exploring the potential of mucin 13 (MUC13) as a biomarker for carcinomas and other diseases
(2018)Mucin 13 (MUC13) is a cell surface glycoprotein aberrantly expressed in a variety of epithelial carcinomas. Thus far, the role of MUC13 in various diseases remains elusive. To the best of our knowledge, this is the first ... -
Global, regional, and national age-sex specifc mortality for 264 causes of death, 1980-2016: A systematic analysis for the Global Burden of Disease Study 2016
(2017)Background: Monitoring levels and trends in premature mortality is crucial to understanding how societies can address prominent sources of early death. The Global Burden of Disease 2016 Study (GBD 2016) provides a comprehensive ... -
How can we effectively address the paraneoplastic dermatomyositis: Diagnosis, risk factors and treatment options
(2017)Purpose: Dermatomyositis (DM) represents an auto-immune inflammatory myopathy. In this review, we analyzed the incidence of DM as a clinical manifestation highlighting the peculiar clinical and treatment characteristics ... -
Identification of neoplasm-specific signatures of miRNA interactions by employing a systems biology approach
(2022)MicroRNAs represent major regulatory components of the disease epigenome and they constitute powerful biomarkers for the accurate diagnosis and prognosis of various diseases, including cancers. The advent of high-throughput ... -
Myeloid-derived suppressor cells in prostate cancer: Present knowledge and future perspectives
(2022)Several lines of research are being investigated to better understand mechanisms implicated in response or resistance to immune checkpoint blockade in prostate cancer (PCa). Myeloid-derived suppressor cells (MDSCs) have ... -
Objective and Subjective Appetite Assessment in Patients with Gynecological Cancer: A Pre- and Post-Operative Pilot Study
(2022)Although appetite and its disorders have been implicated in disease progression and outcomes, ghrelin concentrations, an objective appetite measure, are rarely assessed in patients with gynecological malignancies. The ... -
Physicians’ experience, practice and education, on genetic testing and genetic counseling: a nationwide survey study in Greece
(2022)Genetic testing has been implemented in clinical practice. However, data on physician’s practices and education related to cancer genetics, risk assessment and clinical management in Greece, is limited. In Greece, genetic ... -
The role of MiRNA-21 in gliomas: Hope for a novel therapeutic intervention?
(2020)Gliomas are the most common primary brain tumors in adults. They are generally very resistant to treatment and are therefore associated with negative outcomes. MicroRNAs (miRNAs) are small, non-coding RNA molecules that ... -
Solitary axillary lymph nodal metastasis from primary ovarian cancer: An unusual presentation
(2017)Background: The most common sites of visceral metastases in ovarian cancer are the liver and lungs, whereas the most frequent sites of lymph nodal involvement are abdominal, para-aortic, mediastinal, and pelvic nodes. ...