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Πλοήγηση ανά Θέμα "nucleic acid database"

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    • DIANA-LncBase v2: Indexing microRNA targets on non-coding transcripts 

      Paraskevopoulou M.D., Vlachos I.S., Karagkouni D., Georgakilas G., Kanellos I., Vergoulis T., Zagganas K., Tsanakas P., Floros E., Dalamagas T., Hatzigeorgiou A.G. (2016)
      MicroRNAs (miRNAs) are short non-coding RNAs (ncRNAs) that act as post-transcriptional regulators of coding gene expression. Long non-coding RNAs (lncRNAs) have been recently reported to interact with miRNAs. The sponge-like ...

    • DIANA-LncBase v3: Indexing experimentally supported miRNA targets on non-coding transcripts 

      Karagkouni D., Paraskevopoulou M.D., Tastsoglou S., Skoufos G., Karavangeli A., Pierros V., Zacharopoulou E., Hatzigeorgiou A.G. (2020)
      DIANA-LncBase v3.0 (www.microrna.gr/LncBase) is a reference repository with experimentally supported miRNA targets on non-coding transcripts. Its third version provides approximately half a million entries, corresponding ...

    • DIANA-miRGen v3.0: Accurate characterization of microRNA promoters and their regulators 

      Georgakilas G., Vlachos I.S., Zagganas K., Vergoulis T., Paraskevopoulou M.D., Kanellos I., Tsanakas P., Dellis D., Fevgas A., Dalamagas T., Hatzigeorgiou A.G. (2016)
      MicroRNAs (miRNAs) are small non-coding RNAs that actively fine-tune gene expression. The accurate characterization of the mechanisms underlying miRNA transcription regulation will further expand our knowledge regarding ...

    • DIANA-miRGen v4: Indexing promoters and regulators for more than 1500 microRNAs 

      Perdikopanis N., Georgakilas G.K., Grigoriadis D., Pierros V., Kavakiotis I., Alexiou P., Hatzigeorgiou A. (2021)
      Deregulation of microRNA (miRNA) expression plays a critical role in the transition from a physiological to a pathological state. The accurate miRNA promoter identification in multiple cell types is a fundamental endeavor ...

    • DIANA-miTED: A microRNA tissue expression database 

      Kavakiotis I., Alexiou A., Tastsoglou S., Vlachos I.S., Hatzigeorgiou A.G. (2022)
      microRNAs (miRNAs) are short (∼23nt) single-stranded non-coding RNAs that act as potent post-transcriptional gene expression regulators. Information about miRNA expression and distribution across cell types and tissues is ...

    • DIANA-TarBase v8: A decade-long collection of experimentally supported miRNA-gene interactions 

      Karagkouni D., Paraskevopoulou M.D., Chatzopoulos S., Vlachos I.S., Tastsoglou S., Kanellos I., Papadimitriou D., Kavakiotis I., Maniou S., Skoufos G., Vergoulis T., Dalamagas T., Hatzigeorgiou A.G. (2018)
      DIANA-TarBase v8 (http://www.microrna.gr/tarbase) is a reference database devoted to the indexing of experimentally supported microRNA (miRNA) targets. Its eighth version is the first database indexing >1 million entries, ...

    • Identifying pri-miRNA transcription start sites 

      Georgakilas G., Perdikopanis N., Hatzigeorgiou A.G. (2018)
      MicroRNAs (miRNAs) are small non-coding RNAs that can regulate gene expression playing vital role in nearly all biological pathways. Even though miRNAs have been intensely studied for more than two decades, information ...

    • In silico methods for the identification of diagnostic and favorable prognostic markers in acute myeloid leukemia 

      Yılmaz H., Toy H.I., Marquardt S., Karakülah G., Küçük C., Kontou P.I., Logotheti S., Pavlopoulou A. (2021)
      Acute myeloid leukemia (AML), the most common type of acute leukemia in adults, is mainly asymptomatic at early stages and progresses/recurs rapidly and frequently. These attributes necessitate the identification of ...

    • RNAcentral: A comprehensive database of non-coding RNA sequences 

      Petrov A.I., Kay S.J.E., Kalvari I., Howe K.L., Gray K.A., Bruford E.A., Kersey P.J., Cochrane G., Finn R.D., Bateman A., Kozomara A., Griffiths-Jones S., Frankish A., Zwieb C.W., Lau B.Y., Williams K.P., Chan P.P., Lowe T.M., Cannone J.J., Gutell R.R., Machnicka M.A., Bujnicki J.M., Yoshihama M., Kenmochi N., Chai B., Cole J.R., Szymanski M., Karlowski W.M., Wood V., Huala E., Berardini T.Z., Zhao Y., Chen R., Zhu W., Paraskevopoulou M.D., Vlachos I.S., Hatzigeorgiou A.G., Ma L., Zhang Z., Puetz J., Stadler P.F., McDonald D., Basu S., Fey P., Engel S.R., Cherry J.M., Volders P.-J., Mestdagh P., Wower J., Clark M., Quek X.C., Dinger M.E., The RNAcentral Consortium (2017)
      RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for accessing ncRNA sequences of all ncRNA types from all organisms. Since ...

    • RNAcentral: A hub of information for non-coding RNA sequences 

      Sweeney B.A., Petrov A.I., Burkov B., Finn R.D., Bateman A., Szymanski M., Karlowski W.M., Gorodkin J., Seemann S.E., Cannone J.J., Gutell R.R., Fey P., Basu S., Kay S., Cochrane G., Billis K., Emmert D., Marygold S.J., Huntley R.P., Lovering R.C., Frankish A., Chan P.P., Lowe T.M., Bruford E., Seal R., Vandesompele J., Volders P.-J., Paraskevopoulou M., Ma L., Zhang Z., Griffiths-Jones S., Bujnicki J.M., Boccaletto P., Blake J.A., Bult C.J., Chen R., Zhao Y., Wood V., Rutherford K., Rivas E., Cole J., Laulederkind S.J.F., Shimoyama M., Gillespie M.E., Orlic-Milacic M., Kalvari I., Nawrocki E., Engel S.R., Cherry J.M., Team S., Berardini T.Z., Hatzigeorgiou A., Karagkouni D., Howe K., Davis P., Dinger M., He S., Yoshihama M., Kenmochi N., Stadler P.F., Williams K.P. (2019)
      RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences, collating information on ncRNA sequences of all types from a broad range of organisms. We have recently added a new genome mapping pipeline that ...