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Listar por tema "nuclear magnetic resonance"

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    • Assessment of the antioxidant activity of an olive oil total polyphenolic fraction and hydroxytyrosol from a Greek Olea europea variety in endothelial cells and myoblasts 

      Kouka P., Priftis A., Stagos D., Angelis A., Stathopoulos P., Xinos N., Skaltsounis A.-L., Mamoulakis C., Tsatsakis A.M., Spandidos D.A., Kouretas D. (2017)
      Olive oil (OO) constitutes the basis of the Mediterranean diet, and it seems that its biophenols, such as hydroxytyrosol (HT) may scavenge free radicals, attracting distinct attention due to their beneficial effects in ...

    • Evidence for Novel Action at the Cell-Binding Site of Human Angiogenin Revealed by Heteronuclear NMR Spectroscopy, in silico and in vivo Studies 

      Chatzileontiadou D.S.M., Tsika A.C., Diamantopoulou Z., Delbé J., Badet J., Courty J., Skamnaki V.T., Parmenopoulou V., Komiotis D., Hayes J.M., Spyroulias G.A., Leonidas D.D. (2018)
      A member of the ribonuclease A superfamily, human angiogenin (hAng) is a potent angiogenic factor. Heteronuclear NMR spectroscopy combined with induced-fit docking revealed a dual binding mode for the most antiangiogenic ...

    • Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X-ray Crystallography 

      Szabó K.E., Kyriakis E., Psarra A.-M.G., Karra A.G., Sipos Á., Docsa T., Stravodimos G.A., Katsidou E., Skamnaki V.T., Liggri P.G.V., Zographos S.E., Mándi A., Király S.B., Kurtán T., Leonidas D.D., Somsák L. (2019)
      Epimeric series of aryl-substituted glucopyranosylidene-spiro-imidazolinones, an unprecedented new ring system, were synthesized from the corresponding Schiff bases of O-perbenzoylated (gluculopyranosylamine)onamides by ...

    • Magnetic resonance morphometry of the adult normal lumbar intervertebral space 

      Fyllos A.H., Arvanitis D.L., Karantanas A.H., Varitimidis S.E., Hantes M., Zibis A.H. (2018)
      Purpose: This study aims to: (a) quantify and evaluate normal relationships between neighboring spinal units using MR imaging indices, (b) propose an easy-to-apply-and-reproduce method of estimating the correct amount of ...

    • Marilines A-C: Novel phthalimidines from the sponge-derived fungus Stachylidium sp 

      Almeida, C.; Hemberger, Y.; Schmitt, S. M.; Bouhired, S.; Natesan, L.; Kehraus, S.; Dimas, K.; Gütschow, M.; Bringmann, G.; König, G. M. (2012)
      A marine-derived fungus of the genus Stachylidium was isolated from the sponge Callyspongia cf. C. flammea. Chemical investigation of the bioactive fungal extract led to the isolation of the novel phthalimidine derivatives ...

    • NMR study of Met-1 human Angiogenin: 1H, 13C, 15N backbone and side-chain resonance assignment 

      Tsika A.C., Chatzileontiadou D.S.M., Leonidas D.D., Spyroulias G.A. (2016)
      Here, we report the high yield expression and preliminary structural analysis via solution hetero-nuclear NMR spectroscopy of the recombinant Met-1 human Angiogenin. The analysis reveals a well folded as well as, a monomeric ...

    • Plant terpenoid metabolism co-opts a component of the cell wall biosynthesis machinery 

      Jozwiak A., Sonawane P.D., Panda S., Garagounis C., Papadopoulou K.K., Abebie B., Massalha H., Almekias-Siegl E., Scherf T., Aharoni A. (2020)
      Glycosylation is one of the most prevalent molecular modifications in nature. Single or multiple sugars can decorate a wide range of acceptors from proteins to lipids, cell wall glycans and small molecules, dramatically ...

    • Prediction of Early Recurrent Thromboembolic Event and Major Bleeding in Patients with Acute Stroke and Atrial Fibrillation by a Risk Stratification Schema: The ALESSA Score Study 

      Paciaroni M., Agnelli G., Caso V., Tsivgoulis G., Furie K.L., Tadi P., Becattini C., Falocci N., Zedde M., Abdul-Rahim A.H., Lees K.R., Alberti A., Venti M., Acciarresi M., D'Amore C., Mosconi M.G., Cimini L.A., Procopio A., Bovi P., Carletti M., Rigatelli A., Cappellari M., Putaala J., Tomppo L., Tatlisumak T., Bandini F., Marcheselli S., Pezzini A., Poli L., Padovani A., Masotti L., Vannucchi V., Sohn S.-I., Lorenzini G., Tassi R., Guideri F., Acampa M., Martini G., Ntaios G., Karagkiozi E., Athanasakis G., Makaritsis K., Vadikolias K., Liantinioti C., Chondrogianni M., Mumoli N., Consoli D., Galati F., Sacco S., Carolei A., Tiseo C., Corea F., Ageno W., Bellesini M., Colombo G., Silvestrelli G., Ciccone A., Scoditti U., Denti L., Mancuso M., Maccarrone M., Orlandi G., Giannini N., Gialdini G., Tassinari T., De Lodovici M.L., Bono G., Rueckert C., Baldi A., D'Anna S., Toni D., Letteri F., Giuntini M., Lotti E.M., Flomin Y., Pieroni A., Kargiotis O., Karapanayiotides T., Monaco S., Baronello M.M., Csiba L., Szabó L., Chiti A., Giorli E., Del Sette M., Imberti D., Zabzuni D., Doronin B., Volodina V., Michel P., Vanacker P., Barlinn K., Pallesen L.-P., Kepplinger J., Bodechtel U., Gerber J., Deleu D., Melikyan G., Ibrahim F., Akhtar N., Gourbali V., Yaghi S. (2017)
      Background and Purposes - This study was designed to derive and validate a score to predict early ischemic events and major bleedings after an acute ischemic stroke in patients with atrial fibrillation. Methods - The ...