Πλοήγηση ανά Θέμα "neutropenia"

Association of ITPA gene polymorphisms with adverse effects of AZA/6-MP administration: a systematic review and meta-analysis

Barba E., Kontou P.I., Michalopoulos I., Bagos P.G., Braliou G.G. (2022)

Azathioprine (AZA) and its metabolite, mercaptopurine (6-MP), are widely used immunosuppressant drugs. Polymorphisms in genes implicated in AZA/6-MP metabolism, reportedly, could account in part for their potential toxicity. ...

COVID-19 among children with cancer in Greece (2020): Results from the Nationwide Registry of Childhood Hematological Malignancies and Solid Tumors (NARECHEM-ST)

Baka M., Michos A., Alexopoulou A., Bouka P., Bouka E., Dana E., Dimitriou G., Doganis, Grivea I., Ioannidou M., Kourti M., Magkou E., Makis A., Malama A., Mantadakis E., Markozannes G., Mitsios A., Moschovi M., Papadakis V., Panagopoulou P., Papakonstantinou E., Papadopoulos S., Polychronopoulou S., Themistocleous M., Tzotzola V., Ntzani E., Petridou E.T. (2021)

[No abstract available]

The effect of 5-azacytidine treatment delays and dose reductions on the prognosis of patients with myelodysplastic syndrome: how to optimize treatment results and outcomes

Diamantopoulos P.T., Symeonidis A., Pappa V., Kotsianidis I., Galanopoulos A., Pontikoglou C., Anagnostopoulos A., Vassilopoulos G., Zikos P., Hatzimichael E., Papaioannou M., Megalakaki A., Repousis P., Kotsopoulou M., Dimou M., Solomou E., Dryllis G., Tsokanas D., Papoutselis M.-K., Papageorgiou S., Kyrtshonis M.-C., Kourakli A., Papadaki H., Panayiotidis P., Viniou N.-A. (2021)

The regimen of 5-azacytidine for patients with myelodysplastic syndrome (MDS) has remained unchanged since its first approval. Although several modifications have since been made and delays and dose reductions are common ...

Erythema Multiforme Associated with Respiratory Disease in a Commercial Breeding Pig Herd

Papatsiros V.G., Athanasiou L.V., Psalla D., Petridou E., Maragkakis G.G., Papatsas I., Arsenakis I., Maes D. (2015)

This study describes an erythema multiforme (EM) in breeding sows, after their mixing in the group housing system. Sows at 30-35 days of gestation showed red and raised skin areas, depression, anorexia, fever, respiratory ...

Evaluating Alternative Ramucirumab Doses as a Single Agent or with Paclitaxel in Second-Line Treatment of Locally Advanced or Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma: Results from Two Randomized, Open-Label, Phase II Studies

Shah M.A., Udrea A.A., Bondarenko I., Mansoor W., Sánchez R.G., Sarosiek T., Bozzarelli S., Schenker M., Gomez-Martin C., Morgan C., Özgüroğlu M., Pikiel J., Kalofonos H.P., Wojcik E., Buchler T., Swinson D., Cicin I., Joseph M., Vynnychenko I., Luft A.V., Enzinger P.C., Salek T., Papandreou C., Tournigand C., Maiello E., Wei R., Ferry D., Gao L., Oliveira J.M., Ajani J.A. (2022)

Studies JVDB and JVCZ examined alternative ramucirumab dosing regimens as monotherapy or combined with paclitaxel, respectively, in patients with advanced/metastatic gastric/gastroesophageal junction (GEJ) adenocarcinoma. ...

Hematological features in sheep with igg and igm antibodies against borrelia burgdorferi sensu lato

Athanasiou L.V., Spanou V.M., Katsogiannou E.G., Katsoulos P.D. (2021)

Exposure of sheep to Borrelia burgdorferi sensu lato (s.I.) complex, the causative agent of Lyme borreliosis (LB), has been reported in tick-abundant areas worldwide, while no data have been reported in Greece. The aim of ...

Histograms of Complete Blood Counts in Dogs: Maximizing Diagnostic Information

Athanasiou L.V., Tsokana C.N., Pardali D., Moraitou K.A. (2018)

Histograms, which are an integral part of the automated complete blood count, are now available through most of the automatic hematology analyzers used in veterinary clinical practice. Data concerning the size and number ...

Lessons from pathophysiology: Use of individualized combination treatments with immune interventional agents to tackle severe respiratory failure in patients with COVID-19

Dalekos G.N., Stefos A., Georgiadou S., Lygoura V., Michail A., Ntaios G., Samakidou A., Giannoulis G., Gabeta S., Vlychou M., Petinaki E., Leventogiannis K., Giamarellos-Bourboulis E.J., Gatselis N.K. (2021)

Aims Infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) may lead to the development of severe respiratory failure. In hospitalized-patients, prompt interruption of the virus-driven inflammatory process ...

Management of covid-19 patients in the emergency department

Pantazopoulos I., Tsikrika S., Kolokytha S., Manos E., Porpodis K. (2021)

COVID-19 is an emerging disease of global public health concern. As the pandemic overwhelmed emergency departments (EDs), a restructuring of emergency care delivery became necessary in many hospitals. Furthermore, with ...

Patients with haemoglobinopathies and chronic hepatitis C: A real difficult to treat population in 2016?

Zachou K., Arvaniti P., Gatselis N.K., Azariadis K., Papadamou G., Rigopoulou E., Dalekos G.N. (2017)

Background & objectives: In the past, patients with haemoglobinopathies were at high risk of acquiring hepatitis C virus (HCV) due to multiple transfusions before HCV screening. In these patients, the coexistence of ...

A prospective epidemiological, clinical, and clinicopathologic study of feline leukemia virus and feline immunodeficiency virus infection in 435 cats from Greece

Kokkinaki K.G., Saridomichelakis M.N., Leontides L., Mylonakis M.E., Konstantinidis A.O., Steiner J.M., Suchodolski J.S., Xenoulis P.G. (2021)

Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are retroviruses causing significant morbidity and mortality in cats. The aim of this study was to describe the epidemiological, clinical and clinicopathologic ...

The proteasome as a target for cancer treatment: Focus on bortezomib

Papandreou, C. N. (2005)

Targeted degradation of key regulatory proteins is an essential element of cell-cycle control. The proteasome plays a pivotal role in the degradation of such proteins and has, therefore, become an important therapeutic ...

Quantitative and Morphological Blood Cell Findings Associated with the Presence of Antigen and/or Antibodies against Anaplasma phagocytophilum in Sheep

Katsogiannou E.G., Katsoulos P.D., Christodoulopoulos G., Polizopoulou Z.S., Papadakis S.M., Kokkinaki K.C., Billinis C., Boutsini S., Stougiou D., Athanasiou L.V. (2021)

Anaplasma phagocytophilum is the causative agent of a disease known as tick borne fever in sheep, although fever is not always present. Due to inconclusive clinical signs, diagnosis is based on the cytological or molecular ...

Real world data on the prognostic significance of monocytopenia in myelodysplastic syndrome

Diamantopoulos P.T., Charakopoulos E., Symeonidis A., Kotsianidis I., Viniou N.-A., Pappa V., Pontikoglou C., Tsokanas D., Drakos G., Kourakli A., Solomou E., Hatzimichael E., Pouli A., Kotsopoulou M., Asmanis E., Dimou M., Panayiotidis P., Papageorgiou S., Vassilopoulos G., Anagnostopoulos A., Vassilakopoulos T., Papadaki H., Galanopoulos A. (2022)

Monocytopenia is a common finding in patients with myelodysplastic syndrome (MDS), but although monocytes may exhibit prognostic significance in MDS due to their role in innate immunity, they have not been incorporated in ...

Real-world data on prognosis and outcome of primary plasma cell leukemia in the era of novel agents: A multicenter national study by the Greek Myeloma Study Group

Katodritou E., Terpos E., Delimpasi S., Kotsopoulou M., Michalis E., Vadikolia C., Kyrtsonis M.-C., Symeonidis A., Giannakoulas N., Vadikolia C., Michael M., Kalpadakis C., Gougopoulou T., Prokopiou C., Kaiafa G., Christoulas D., Gavriatopoulou M., Giannopoulou E., Labropoulou V., Verrou E., Kastritis E., Konstantinidou P., Anagnostopoulos A., Dimopoulos M.A. (2018)

We have studied the efficacy and the prognostic impact of novel agents in 50 primary plasma cell leukemia (pPCL) patients registered in our database. Eighty percent of patients were treated upfront with novel agent-based ...

Steroid-responsive neutropenia in a cat with progressive feline leukemia virus infection

Stavroulaki E.M., Mylonakis M.E., Papanikolaou E., Hatzis A., Xenoulis P.G. (2020)

An 8-month-old female domestic shorthair cat was presented to the Animal Medical Center with anorexia, lethargy, and mild gastrointestinal signs. A CBC revealed a profound neutropenia, and serologic testing with an in-house ...

Taxane & cyclophosphamide vs anthracycline & taxane-based chemotherapy as adjuvant treatment for breast cancer: A pooled analysis of randomized controlled trias by the hellenic academy of oncology

Ntellas P., Spathas N., Agelaki S., Zintzaras E., Saloustros E. (2019)

Background: Adjuvant chemotherapy has an indisputable value for early breast cancer patients. Anthracycline and taxane-based regimens (TaxAC) have not been proven superior to taxane & cyclophosphamide (TC), a less toxic ...

Type 1 autoimmune hepatitis presenting with severe autoimmune neutropenia

Doumtsis P., Oikonomou T., Goulis I., Zachou K., Dalekos G., Cholongitas E. (2018)

Autoimmune hepatitis (AIH) is a progressive, chronic liver disease characterized by unresolving hepatocellular inflammation of autoimmune origin. The clinical spectrum may vary from asymptomatic presentation, to non-specific ...

Unnecessary diagnostic investigations in benign acute childhood myositis: A case series report

Neocleous, C.; Spanou, C.; Mpampalis, E.; Xatzigeorgiou, S.; Pavlidou, C.; Poulos, E.; Tzanetis, F. (2012)

Benign acute childhood myositis (BACM) is a rare, acute, self-limiting muscle disorder, mainly affecting school-aged boys, with an excellent prognosis, requiring no therapeutic intervention. We report a series of seven ...