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Πλοήγηση ανά Θέμα "leukocyte elastase"

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    • Incorporating Biomarkers in COPD Management: The Research Keeps Going 

      Pantazopoulos I., Magounaki K., Kotsiou O., Rouka E., Perlikos F., Kakavas S., Gourgoulianis K. (2022)
      Globally, chronic obstructive pulmonary disease (COPD) remains a major cause of morbidity and mortality, having a significant socioeconomic effect. Several molecular mechanisms have been related to COPD including chronic ...

    • Marilines A-C: Novel phthalimidines from the sponge-derived fungus Stachylidium sp 

      Almeida, C.; Hemberger, Y.; Schmitt, S. M.; Bouhired, S.; Natesan, L.; Kehraus, S.; Dimas, K.; Gütschow, M.; Bringmann, G.; König, G. M. (2012)
      A marine-derived fungus of the genus Stachylidium was isolated from the sponge Callyspongia cf. C. flammea. Chemical investigation of the bioactive fungal extract led to the isolation of the novel phthalimidine derivatives ...

    • Systemic Biomarkers of Collagen and Elastin Turnover Are Associated With Clinically Relevant Outcomes in COPD 

      Stolz D., Leeming D.J., Kristensen J.H.E., Karsdal M.A., Boersma W., Louis R., Milenkovic B., Kostikas K., Blasi F., Aerts J., Sand J.M.B., Wouters E.F.M., Rohde G., Prat C., Torres A., Welte T., Roth M., Papakonstantinou E., Tamm M. (2017)
      Background Extracellular matrix (ECM) remodeling of the lung tissue releases protein fragments into the blood, where they may be detected as serologic surrogate markers of disease activity in COPD. Our goal was to assess ...