Πλοήγηση ανά Θέμα "immunoregulation"

The challenges of primary biliary cholangitis: What is new and what needs to be done

Terziroli Beretta-Piccoli B., Mieli-Vergani G., Vergani D., Vierling J.M., Adams D., Alpini G., Banales J.M., Beuers U., Björnsson E., Bowlus C., Carbone M., Chazouillères O., Dalekos G., De Gottardi A., Harada K., Hirschfield G., Invernizzi P., Jones D., Krawitt E., Lanzavecchia A., Lian Z.-X., Ma X., Manns M., Mavilio D., Quigley E.M., Sallusto F., Shimoda S., Strazzabosco M., Swain M., Tanaka A., Trauner M., Tsuneyama K., Zigmond E., Gershwin M.E. (2019)

Primary Biliary Cholangitis (PBC) is an uncommon, chronic, cholangiopathy of autoimmune origin and unknown etiology characterized by positive anti-mitochondrial autoantibodies (AMA), female preponderance and progression ...

Chios mastic gum: A plant-produced resin exhibiting numerous diverse pharmaceutical and biomedical prοperties

Dimas, K. S.; Pantazis, P.; Ramanujam, R. (2012)

Chios mastic gum (CMG) is a resin produced by the plant Pistacia lentiscus var. chia. CMG is used to extract the mastic gum essential oil (MGO). CMG and MGO consist of nearly 70 constituents and have demonstrated numerous ...

Delphinidin diminishes in vitro interferon-γ and interleukin-17 producing cells in patients with psoriatic disease

Tsiogkas S.G., Mavropoulos Α., Skyvalidas D.N., Patrikiou E., Ntavari N., Daponte A.I., Grammatikopoulou M.G., Dardiotis E., Roussaki-Schulze A.-V., Sakkas L.I., Zafiriou E., Bogdanos D.P. (2022)

The anthocyanidin delphinidin reduces psoriasiform lesions and inflammatory mediators in human cell culture systems. Its role in psoriatic disease has not yet been investigated. We assessed delphinidin’s in vitro ...

Editorial: Role of Ribonucleases in Immune Response Regulation During Infection and Cancer

Boix E., Acquati F., Leonidas D., Pulido D. (2020)

[No abstract available]

The effect of Apremilast on signal transduction and IL-10 production in CD39high regulatory B cells in patients with psoriatic arthritis

Sakkas L.I., Mavropoulos A., Zafiriou E., Roussaki-Schulze A., Bogdanos D.P. (2018)

Background. IL-10-producing regulatory B cells (Bregs) are of great importance in autoimmunity, as they inhibit proinflammatory T cells. We have shown that IL-10-producing Bregs in psoriatic arthritis(PsA) were decreased ...

Evidence of a Redox-Dependent Regulation of Immune Responses to Exercise-Induced Inflammation

Sakelliou A., Fatouros I.G., Athanailidis I., Tsoukas D., Chatzinikolaou A., Draganidis D., Jamurtas A.Z., Liacos C., Papassotiriou I., Mandalidis D., Stamatelopoulos K., Dimopoulos M.A., Mitrakou A. (2016)

We used thiol-based antioxidant supplementation (n-acetylcysteine, NAC) to determine whether immune mobilisation following skeletal muscle microtrauma induced by exercise is redox-sensitive in healthy humans. According to ...

The hygiene hypothesis and evolutionary medicine

Germenis, A. E. (2014)

The hygiene hypothesis is an explanatory model for increases in the incidence of chronic inflammatory disorders which have become much more prevalent in developed countries during recent last decades. Accumulating evidence ...

Immune-Related Gene Polymorphisms and Pharmacogenetic Studies in Nephrology

Tziastoudi M., Cholevas C., Stefanidis I., Theoharides T.C. (2021)

A large subgroup of patients with chronic kidney disease still encounter serious adverse effects and lack of responsiveness to medications, possibly because of the interindividual genetic variability in genes involved in ...

The immunopathogenetic role of autoantibodies in canine autoimmune hepatitis: Lessons to learn from human autoimmune hepatitis

Liaskos, C.; Mavropoulos, A.; Orfanidou, T.; Spyrou, V.; Athanasiou, L. V.; Billinis, C. (2012)

Autoimmune hepatitis (AIH) is not a disease entity restricted to man, but it can be found in other animals including canines. An increasing number of studies have focused on the immunopathogenesis of human autoimmune ...

On the immunoregulatory role of statins in multiple sclerosis: the effects on Th17 cells

Ntolkeras G., Barba C., Mavropoulos A., Vasileiadis G.K., Dardiotis E., Sakkas L.I., Hadjigeorgiou G., Bogdanos D.P. (2019)

Statins, the cholesterol-lowering drugs, also possess immunomodulatory properties, affecting among others T cell activation and differentiation, antigen presentation, and regulatory T cell (Tregs) maintenance and ...

On the Role of Salt in Immunoregulation and Autoimmunity

Mavropoulos A. (2021)

[No abstract available]

p38 mitogen-activated protein kinase impairment of innate immune cells is a characteristic feature of HBeAg-negative chronic hepatitis B

Bakarozi M., Mavropoulos A., Bogdanos D.P., Dalekos G.N., Rigopoulou E.I. (2020)

The mitogen-activated protein kinase p38 (MAPK) is implicated in the induction of immune responses by regulating the differentiation of T lymphocytes and production of cytokines. Our aim was to investigate p38MAPK ...

The role of platelets in autoimmunity, vasculopathy, and fibrosis: Implications for systemic sclerosis

Ntelis K., Solomou E.E., Sakkas L., Liossis S.-N., Daoussis D. (2017)

Introduction Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy, autoimmunity, and widespread dermal and visceral fibrosis. This article summarizes the current knowledge about the potential ...