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    • Belimumab is a promising third-line treatment option for refractory autoimmune hepatitis 

      Arvaniti P., Giannoulis G., Gabeta S., Zachou K., Koukoulis G.K., Dalekos G.N. (2020)
      Background & Aims: Autoimmune hepatitis (AIH) is a disease of unknown aetiology with a favourable response to immunosuppression. However, in the clinic, it appears that <50% of patients achieve complete response on standard ...

    • COVID-19 immunopathology and the central nervous system: Implication for multiple sclerosis and other autoimmune diseases with associated demyelination 

      Boziki M.K., Mentis A.-F.A., Shumilina M., Makshakov G., Evdoshenko E., Grigoriadis N. (2020)
      In the frame of the coronavirus disease 2019 (COVID-19) pandemic, recent reports on SARS-CoV-2 potential neuroinvasion placed neurologists on increased alertness in order to assess early neurological manifestations and ...

    • COVID-19 pandemic and cardiovascular disease: where do we stand? 

      Chatzis D.G., Magounaki K.T., Pantazopoulos I.N., Johnson E.O., Tsioufis K.P. (2020)
      Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19) which recently has been characterized as a pandemic by the World Health Organization (WHO) having killed ...

    • Drug genetic associations with COVID-19 manifestations: a data mining and network biology approach 

      Charitou T., Kontou P.I., Tamposis I.A., Pavlopoulos G.A., Braliou G.G., Bagos P.G. (2022)
      Available drugs have been used as an urgent attempt through clinical trials to minimize severe cases of hospitalizations with Coronavirus disease (COVID-19), however, there are limited data on common pharmacogenomics ...

    • Incidence, risk factors and validation of the RABBIT score for serious infections in a cohort of 1557 patients with rheumatoid arthritis 

      Thomas K., Lazarini A., Kaltsonoudis E., Voulgari P.V., Drosos A.A., Repa A., Sali A.M.I., Sidiropoulos P., Tsatsani P., Gazi S., Evangelia A., Boki K.A., Katsimbri P., Boumpas D., Fragkiadaki K., Tektonidou M.G., Sfikakis P.P., Karagianni K., Sakkas L.I., Grika E.P., Vlachoyiannopoulos P.G., Evangelatos G., Iliopoulos A., Dimitroulas T., Garyfallos A., Melissaropoulos K., Georgiou P., Areti M., Georganas C., Vounotrypidis P., Georgiopoulos G., Kitas G.D., Vassilopoulos D. (2021)
      Objectives: Predicting serious infections (SI) in patients with rheumatoid arthritis (RA) is crucial for the implementation of appropriate preventive measures. Here we aimed to identify risk factors for SI and to validate ...

    • Interleukin-6 inhibitors reduce mortality in coronavirus disease-2019: An individual patient data meta-analysis from randomized controlled trials 

      Tasoudis P.T., Arvaniti C.K., Adamou A.T., Belios I., Stone J.H., Horick N., Sagris D., Dalekos G.N., Ntaios G. (2022)
      Objective: To assess the efficacy of IL-6 inhibitors compared to standard of care (SOC) in COVID-19 patients. Data Sources: A systematic review of the MEDLINE and Scopus databases (last search: October 8th, 2021) was ...

    • Major vault protein/lung resistance related protein: A novel biomarker for rheumatoid arthritis 

      Marinou D., Katsifis G., Barouta G., Liaskos C., Sakkas L.I., Tsakris A., Routsias J.G. (2021)
      Objective Rheumatoid arthritis (RA) can lead to joint destruction and early institution of effective treatment can preserve joint function. Biomarkers can establish early diagnosis and predict effect of treatment. Vault ...

    • Platelets in Systemic Sclerosis: the Missing Link Connecting Vasculopathy, Autoimmunity, and Fibrosis? 

      Ntelis K., Bogdanos D., Dimitroulas T., Sakkas L., Daoussis D. (2019)
      Purpose of Review: Platelets are no longer recognized solely as cell fragments regulating hemostasis. They have pleiotropic functions and they are linked directly or indirectly with the three cornerstones of systemic ...

    • Postdischarge thromboembolic outcomes and mortality of hospitalized patients with COVID-19: the CORE-19 registry 

      Giannis D., Allen S.L., Tsang J., Flint S., Pinhasov T., Williams S., Tan G., Thakur R., Leung C., Snyder M., Bhatia C., Garrett D., Cotte C., Isaacs S., Gugerty E., Davidson A., Marder G.S., Schnitzer A., Goldberg B., McGinn T., Davidson K.W., Barish M.A., Qiu M., Zhang M., Goldin M., Matsagkas M., Arnaoutoglou E., Spyropoulos A.C. (2021)
      Thromboembolic events, including venous thromboembolism (VTE) and arterial thromboembolism (ATE), and mortality from subclinical thrombotic events occur frequently in coronavirus disease 2019 (COVID-19) inpatients. Whether ...

    • Primary sjögren’s syndrome and cardiovascular disease 

      Melissaropoulos K., Bogdanos D., Dimitroulas T., Sakkas L.I., Kitas G.D., Daoussis D. (2020)
      Sjögren’s syndrome is a rheumatic autoimmune disease that primarily affects middle-aged women and runs a slowly progressing course with sicca symptoms being the prevalent manifestation. Premature atherosclerosis and increased ...

    • Real-world safety and efficacy data of immunotherapy in patients with cancer and autoimmune disease: the experience of the Hellenic Cooperative Oncology Group 

      Fountzilas E., Lampaki S., Koliou G.-A., Koumarianou A., Levva S., Vagionas A., Christopoulou A., Laloysis A., Psyrri A., Binas I., Mountzios G., Kentepozidis N., Kotsakis A., Saloustros E., Boutis A., Nikolaidi A., Fountzilas G., Georgoulias V., Chrysanthidis M., Kotteas E., Vo H., Tsiatas M., Res E., Linardou H., Daoussis D., Bompolaki I., Andreadou A., Papaxoinis G., Spyratos D., Gogas H., Syrigos K.N., Bafaloukos D. (2022)
      Background: Data on the safety and efficacy of immune checkpoint inhibitors (ICI) in patients with concurrent autoimmune diseases (AID) are limited. Methods: We performed a retrospective multicenter review of medical records ...

    • Relationship between SARS-CoV-2 infection and the incidence of ventilator-associated lower respiratory tract infections: a European multicenter cohort study 

      Rouzé A., Martin-Loeches I., Povoa P., Makris D., Artigas A., Bouchereau M., Lambiotte F., Metzelard M., Cuchet P., Boulle Geronimi C., Labruyere M., Tamion F., Nyunga M., Luyt C.-E., Labreuche J., Pouly O., Bardin J., Saade A., Asfar P., Baudel J.-L., Beurton A., Garot D., Ioannidou I., Kreitmann L., Llitjos J.-F., Magira E., Mégarbane B., Meguerditchian D., Moglia E., Mekontso-Dessap A., Reignier J., Turpin M., Pierre A., Plantefeve G., Vinsonneau C., Floch P.-E., Weiss N., Ceccato A., Torres A., Duhamel A., Nseir S., Favory R., Preau S., Jourdain M., Poissy J., Bouras C., Saint Leger P., Fodil H., Aptel F., Van Der Linden T., Thille A.W., Azoulay E., Pène F., Razazi K., Bagate F., Contou D., Voiriot G., Thevenin D., Guidet B., Le Guennec L., Kouatchet A., Ehrmann S., Brunin G., Morawiec E., Boyer A., Argaud L., Voicu S., Nieszkowska A., Kowalski B., Goma G., Diaz E., Morales L., Tsolaki V., Gtavriilidis G., Mentzelopoulos S.D., Nora D., Boyd S., Coelho L., Maizel J., Du Cheyron D., Imouloudene M., Quenot J.-P., Guilbert A., Cilloniz C., on behalf of the coVAPid study Group (2021)
      Purpose: Although patients with SARS-CoV-2 infection have several risk factors for ventilator-associated lower respiratory tract infections (VA-LRTI), the reported incidence of hospital-acquired infections is low. We aimed ...

    • The second greek–israeli symposium on autoimmunity and rheumatology: Success through synergy 

      Sakkas L.I., Bogdanos D.P., Boumpas D., Mamouris Z., Gkoutzourelas A., Mavropoulos A., Tsouris Z., Liossis S.-N., Daoussis D., Vasilopoulos D., Tektonidou M., Tzioufas A., Efthymiou G., Dardiotis E., Kitas G., Sharif K., Blank M., Karussis D., Rimar D., Slobodin G., Porat-Katz B.-S., Vadasz Z., Amital H., Toubi E., Shoenfeld Y. (2019)
      [No abstract available]