Πλοήγηση ανά Θέμα "homeostasis"
Αποτελέσματα 1-20 από 28
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Appetite control across the lifecourse: The acute impact of breakfast drink quantity and protein content. the full4health project
(2020)Understanding the mechanisms of hunger, satiety and how nutrients affect appetite control is important for successful weight management across the lifecourse. The primary aim of this study was to describe acute appetite ... -
BAFF receptor polymorphisms and deficiency in humans
(2021)The BAFF-receptor (BAFFR) is a member of the TNF-receptor family. It is expressed only by B cells and binds BAFF as single ligand, which activates key signaling pathways regulating essential cellular functions, including ... -
Clinical reasoning in patients with lower limb tendinopathy a rehabilitation framework
(2020)Tendinopathy is an “umbrella” term that indicates a load-related, non-rupture injury of the tendon. The etiology of tendinopathy can be considered as multifactorial, and its identification and management have proved to be ... -
Editorial: Nicotine and SARS-CoV-2: COVID-19 may be a disease of the nicotinic cholinergic system
(2020)[No abstract available] -
Editorial: Physiological response to environmental stressors in invertebrates
(2022)[No abstract available] -
Effect of Exogenous Intermittent Recombinant Human PTH 1-34 Administration and Chronic Endogenous Parathyroid Hormone Excess on Glucose Homeostasis and Insulin Sensitivity
(2008)We aimed to evaluate the effects of exogenous intermittent teriparatide (rhPTH 1-34) administration versus the chronic exposure to excess endogenous parathyroid hormone (PTH), as in pHPT, on glucose homeostasis. Two patient ... -
The expression of myeloproliferative neoplasm-associated calreticulin variants depends on the functionality of er-associated degradation
(2019)Background: Mutations in CALR observed in myeloproliferative neoplasms (MPN) were recently shown to be pathogenic via their interaction with MPL and the subsequent activation of the Janus Kinase – Signal Transducer and ... -
Fasting-mediated metabolic and toxicity reprogramming impacts circulating microRNA levels in humans
(2021)It is well-established that long-term fasting improves metabolic health, enhances the total antioxidant capacity and increases well-being. MicroRNAs oversee energy homeostasis and metabolic processes and are widely used ... -
Heat remains unaccounted for in thermal physiology and climate change research
(2017)In the aftermath of the Paris Agreement, there is a crucial need for scientists in both thermal physiology and climate change research to develop the integrated approaches necessary to evaluate the health, economic, ... -
Human white-fat thermogenesis: Experimental and meta-analytic findings
(2021)White adipose tissue (WAT) thermogenic activity may play a role in whole-body energy balance and two of its main regulators are thought to be environmental temperature (Tenv) and exercise. Low Tenv may increase uncoupling ... -
IL-33/ST2 axis in organ fibrosis
(2018)Interleukin 33 (IL-33) is highly expressed in barrier sites, acting via the suppression of tumorigenicity 2 receptor (ST2). IL-33/ST2 axis has long been known to play a pivotal role in immunity and cell homeostasis by ... -
Impact of Interleukin 10 Deficiency on Intestinal Epithelium Responses to Inflammatory Signals
(2021)Interleukin 10 (IL-10) is a pleiotropic, anti-inflammatory cytokine that has a major protective role in the intestine. Although its production by cells of the innate and adaptive immune system has been extensively studied, ... -
Impairment in selenocysteine synthesis as a candidate mechanism of inducible coagulopathy in COVID-19 patients
(2021)Coagulopathy has recently been recognized as a recurring complication of COVID-19, most typically associated with critical illness. There are epidemiological, mechanistic and transcriptomic evidence that link Selenium with ... -
Irrigation of radish (Raphanus sativus L.) with microcystin-enriched water holds low risk for plants and their associated rhizopheric and epiphytic microbiome
(2020)Microcystins (MCs) are toxins produced during cyanobacterial blooms. They reach soil and translocated to plants through irrigation of agricultural land with water from MC-impacted freshwater systems. To date we have good ... -
Microcirculation-mediated preconditioning and intracellular hypothermia
(2018)Microcirculation is a network of perfused capillaries that connects macrocirculation with the cells. Although research has provided insight into microcirculatory blood flow, our knowledge remains limited. In this article, ... -
Mycobacterial immunomodulation and viral manipulation of neuronal copper efflux in the setting of sporadic Parkinson's disease: A multi – hit, outside – in hypothesis of its pathogenesis
(2020)Following Braak's hypothesis on the infectious pathogenesis of sporadic Parkinson's disease (sPD), several bacteria and viruses have been investigated as likely culprits. Recent research has focused on neuroinvasive influenza ... -
Nicotinamide riboside supplementation dysregulates redox and energy metabolism in rats: Implications for exercise performance
(2018)New Findings: What is the central question of this study? The aim was to investigate the potential metabolic and redox mechanisms that impaired exercise performance after 21 days of supplementation with 300 mg (kg body ... -
Nicotinic cholinergic system and covid-19: In silico identification of an interaction between sars-cov-2 and nicotinic receptors with potential therapeutic targeting implications
(2020)While SARS-CoV-2 uses angiotensin converting enzyme 2 (ACE2) as the receptor for cell entry, it is important to examine other potential interactions between the virus and other cell receptors. Based on the clinical observation ... -
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Oxidative Stress and Acute Kidney Injury in Critical Illness: Pathophysiologic Mechanisms - Biomarkers - Interventions, and Future Perspectives
(2017)Acute kidney injury (AKI) is a multifactorial entity that occurs in a variety of clinical settings. Although AKI is not a usual reason for intensive care unit (ICU) admission, it often complicates critically ill patients' ...