• Genetic growth potential interacts with nutrition on the ability of mice to cope with Heligmosomoides bakeri infection 

      Coltherd, J. C.; Bnger, L.; Kyriazakis, I.; Houdijk, J. G. M. (2009)
      Artificial selection for improved productivity may reduce an animal's ability to cope with pathogens. Here, we used Roslin mice, uniquely divergently selected for high (ROH) and low (ROL) body weight, to assess interactive ...
    • Genetic variation of eggplant mottled dwarf virus from annual and perennial plant hosts 

      Pappi P.G., Maliogka V.I., Amoutzias G.D., Katis N.I. (2016)
      The genetic diversity of eggplant mottled dwarf virus (EMDV), a member of the family Rhabdoviridae, was studied using isolates collected from different herbaceous and woody plant species and remote geographic areas. Sequences ...
    • Positive selection and precipitation effects on the mitochondrial NADH dehydrogenase subunit 6 gene in brown hares (Lepus europaeus) under a phylogeographic perspective 

      Stefanović M., Djan M., Veličković N., Beuković D., Lavadinović V., Zhelev C.D., Demirbaş Y., Paule L., Gedeon C.I., Mamuris Z., Posautz A., Beiglböck C., Kübber-Heiss A., Suchentrunk F. (2019)
      Previous studies in hares and jackrabbits have indicated that positive selection has shaped the genetic diversity of mitochondrial genes involved in oxidative phosphorylation, which may affect cellular energy production ...
    • Recurrent horizontal transfer identifies mitochondrial positive selection in a transmissible cancer 

      Strakova A., Nicholls T.J., Baez-Ortega A., Ní Leathlobhair M., Sampson A.T., Hughes K., Bolton I.A.G., Gori K., Wang J., Airikkala-Otter I., Allen J.L., Allum K.M., Arnold C.L., Bansse-Issa L., Bhutia T.N., Bisson J.L., Blank K., Briceño C., Castillo Domracheva A., Corrigan A.M., Cran H.R., Crawford J.T., Cutter S.M., Davis E., de Castro K.F., De Nardi A.B., de Vos A.P., Delgadillo Keenan L., Donelan E.M., Espinoza Huerta A.R., Faramade I.A., Fazil M., Fotopoulou E., Fruean S.N., Gallardo-Arrieta F., Glebova O., Gouletsou P.G., Häfelin Manrique R.F., Henriques J.J.G.P., Horta R.S., Ignatenko N., Kane Y., King C., Koenig D., Krupa A., Kruzeniski S.J., Lanza-Perea M., Lazyan M., Lopez Quintana A.M., Losfelt T., Marino G., Martínez Castañeda S., Martínez-López M.F., Masuruli B.M., Meyer M., Migneco E.J., Nakanwagi B., Neal K.B., Neunzig W., Nixon S.J., Ortega-Pacheco A., Pedraza-Ordoñez F., Peleteiro M.C., Polak K., Pye R.J., Ramirez-Ante J.C., Reece J.F., Rojas Gutierrez J., Sadia H., Schmeling S.K., Shamanova O., Sherlock A.G., Steenland-Smit A.E., Svitich A., Tapia Martínez L.J., Thoya Ngoka I., Torres C.G., Tudor E.M., van der Wel M.G., Vițălaru B.A., Vural S.A., Walkinton O., Wehrle-Martinez A.S., Widdowson S.A.E., Zvarich I., Chinnery P.F., Falkenberg M., Gustafsson C.M., Murchison E.P. (2020)
      Autonomous replication and segregation of mitochondrial DNA (mtDNA) creates the potential for evolutionary conflict driven by emergence of haplotypes under positive selection for ‘selfish’ traits, such as replicative ...
    • Sex-specific impact of inbreeding on pathogen load in the striped dolphin 

      Gkafas G.A., de Jong M., Exadactylos A., Raga J.A., Aznar F.J., Rus Hoelzel A. (2020)
      The impact of inbreeding on fitness has been widely studied and provides consequential inference about adaptive potential and the impact on survival for reduced and fragmented natural populations. Correlations between ...
    • Somatic evolution and global expansion of an ancient transmissible cancer lineage 

      Baez-Ortega A., Gori K., Strakova A., Allen J.L., Allum K.M., Bansse-Issa L., Bhutia T.N., Bisson J.L., Briceño C., Domracheva A.C., Corrigan A.M., Cran H.R., Crawford J.T., Davis E., De Castro K.F., De Nardi A.B., De Vos A.P., Keenan L.D., Donelan E.M., Espinoza Huerta A.R., Faramade I.A., Fazil M., Fotopoulou E., Fruean S.N., Gallardo-Arrieta F., Glebova O., Gouletsou P.G., Häfelin Manrique R.F., Henriques J.J.G.P., Horta R.S., Ignatenko N., Kane Y., King C., Koenig D., Krupa A., Kruzeniski S.J., Kwon Y.-M., Lanza-Perea M., Lazyan M., Lopez Quintana A.M., Losfelt T., Marino G., Castañeda S.M., Martínez-López M.F., Meyer M., Migneco E.J., Nakanwagi B., Neal K.B., Neunzig W., Leathlobhair M.N., Nixon S.J., Ortega-Pacheco A., Pedraza-Ordoñez F., Peleteiro M.C., Polak K., Pye R.J., Reece J.F., Gutierrez J.R., Sadia H., Schmeling S.K., Shamanova O., Sherlock A.G., Stammnitz M., Steenland-Smit A.E., Svitich A., Tapia Martínez L.J., Ngoka I.T., Torres C.G., Tudor E.M., Van Der Wel M.G., Viţălaru B.A., Vural S.A., Walkinton O., Wang J., Wehrle-Martinez A.S., Widdowson S.A.E., Stratton M.R., Alexandrov L.B., Martincorena I., Murchison E.P. (2019)
      The canine transmissible venereal tumor (CTVT) is a cancer lineage that arose several millennia ago and survives by “metastasizing” between hosts through cell transfer. The somatic mutations in this cancer record its ...
    • The structure of feeding behavior in commercial broiler lines selected for different growth rates 

      Howie, J. A.; Tolkamp, B. J.; Avendano, S.; Kyriazakis, I. (2009)
      Selection for increased growth rate in livestock is accompanied by increased requirements for food resources. It has been suggested that more intensively selected birds, such as broilers, have altered food intake control ...
    • A unique hydrophobic cluster near the active site contributes to differences in borrelidin inhibition, among threonyl-tRNA synthetases 

      Ruan, B.; Bovee, M. L.; Sacher, M.; Stathopoulos, C.; Poralla, K.; Francklyn, C. S.; Söll, D. (2005)
      Borrelidin, a compound with anti-microbial and anti-angiogenic properties, is a known inhibitor of bacterial and eukaryal threonyl-tRNA synthetase (ThrRS). The inhibition mechanism of borrelidin is not well understood. ...
    • Unravelling the relationship between animal growth and immune response during micro-parasitic infections 

      Doeschl-Wilson, A. B.; Brindle, W.; Emmans, G.; Kyriazakis, I. (2009)
      Background: Both host genetic potentials for growth and disease resistance, as well as nutrition are known to affect responses of individuals challenged with micro-parasites, but their interactive effects are difficult to ...