Πλοήγηση ανά Θέμα "fibronectin"
Αποτελέσματα 1-10 από 10
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Cell and extracellular matrix interaction models in benign mesothelial and malignant pleural mesothelioma cells in 2D and 3D in-vitro
(2021)Malignant pleural mesothelioma (MPM) is an aggressive tumour that grows in the pleural cavity. MPM spheroids released in the pleural fluid can form new tumour foci. Cell–cell, cell–extracellular matrix (ECM) interactions ... -
Epithelial-mesenchymal transition in non small-cell lung cancer
(2017)Background/Aim: Lung cancer is the first cause of cancer related deaths in both males and females. Epithelial-mesenchymal transition (EMT) is a reversible process by which epithelial cells transform to mesenchymal stem ... -
Gene variants of adhesion molecules act as modifiers of disease severity in MS
(2017)Objective: To assess the potential effect of variants in genes encoding molecules that are implicated in leukocyte trafficking into the CNS on the clinical phenotype of multiple sclerosis (MS). Methods: A total of 389 Greek ... -
Gene variants of adhesion molecules predispose to MS: A case-control study
(2019)ObjectiveTo examine the effect of variants in genes encoding molecules that are implicated in leukocyte trafficking into the CNS on the development of MS.MethodsA total of 389 Greek MS cases and 336 controls were recruited ... -
Immunohistochemical expression of extracellular matrix components tenascin, fibronectin, collagen type IV and laminin in breast cancer: their prognostic value and role in tumour invasion and progression
(2002)The immunohistochemical expression of the extracellular matrix (ECM) components tenascin (TN), fibronectin (FN), collagen type IV (Coll) and laminin (LN), and their possible relationships were studied in a series of 134 ... -
Influence of AQP1 on cell adhesion, migration, and tumor sphere formation in malignant pleural mesothelioma is substratum-and histological-type dependent
(2016)Malignant pleural mesothelioma (MPM) is an aggressive cancer. MPM cells express aquaporin-1 (AQP1) that in other cancers has been shown to participate in the tumor metastasis processes. However, in MPM patients AQP1 ... -
Irisin regulates thermogenesis and lipolysis in 3T3-L1 adipocytes
(2022)Background: Adipose tissue plays a pivotal role in the development and progression of the metabolic syndrome which along with its complications is an epidemic of the 21st century. Irisin is an adipo-myokine secreted mainly ... -
Is irisin the new player in exercise-induced adaptations or not? A 2017 update
(2018)Irisin is produced by a proteolytic cleavage of fibronectin type III domain-containing protein 5 (FNDC5) and has emerged as a potential mediator of exercise-induced energy metabolism. The purpose of this study was to review ... -
Traumatic brain injury and gene knockout animal models: An up-to-date review
(2017)Traumatic brain injury (TBI) is a major cause of mortality and morbidity worldwide. Identification of endogenous neuroprotective mechanisms after TBI and the development of therapeutic targets to improve TBI outcomes are ... -
Treatment with long acting muscarinic antagonists stimulates serum levels of irisin in patients with COPD
(2018)Long acting muscarinic antagonists (LAMA) are currently considered the therapeutic mainstay for patients with COPD and have been shown to improve clinical outcomes including symptoms, exercise capacity and airflow limitation. ...