• Antimicrobial activity of bee-collected pollen and beebread: State of the art and future perspectives 

      Didaras N.A., Karatasou K., Dimitriou T.G., Amoutzias G.D., Mossialos D. (2020)
      Bee-collected pollen (BCP) is a well-known functional food. Honey bees process the collected pollen and store it in the hive, inside the comb cells. The processed pollen is called beebread or ambrosia and it is the main ...
    • Cancer's smart bombs: Tumor-derived exosomes target lung epithelial cells triggering pre-metastatic niche formation 

      Antonopoulos D., Balatsos N.A.A., Gourgoulianis K.I. (2017)
      [No abstract available]
    • Myeloid-derived suppressor cells: Major figures that shape the immunosuppressive and angiogenic network in cancer 

      Vetsika E.-K., Koukos A., Kotsakis A. (2019)
      Myeloid-derived suppressor cells (MDSCs) constitute a vast population of immature myeloid cells implicated in various conditions. Most notably, their role in cancer is of great complexity. They exert immunosuppressive ...
    • Non-coding RNAs in cancer-associated cachexia: clinical implications and future perspectives 

      Kottorou A., Dimitrakopoulos F.-I., Tsezou A. (2021)
      Cachexia is a multifactorial syndrome characterized by skeletal muscle loss, with or without adipose atrophy, irreversible through nutritional support, in the context of systemic inflammation and metabolic disorders. It ...
    • Post-COVID-19 Parkinsonism and Parkinson’s Disease Pathogenesis: The Exosomal Cargo Hypothesis 

      Mysiris D.S., Vavougios G.D., Karamichali E., Papoutsopoulou S., Stavrou V.T., Papayianni E., Boutlas S., Mavridis T., Foka P., Zarogiannis S.G., Gourgoulianis K., Xiromerisiou G. (2022)
      Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease after Alzheimer’s disease, globally. Dopaminergic neuron degeneration in substantia nigra pars compacta and aggregation of misfolded alpha-synuclein ...
    • The role of MiRNA-21 in gliomas: Hope for a novel therapeutic intervention? 

      Aloizou A.-M., Pateraki G., Siokas V., Mentis A.-F.A., Liampas I., Lazopoulos G., Kovatsi L., Mitsias P.D., Bogdanos D.P., Paterakis K., Dardiotis E. (2020)
      Gliomas are the most common primary brain tumors in adults. They are generally very resistant to treatment and are therefore associated with negative outcomes. MicroRNAs (miRNAs) are small, non-coding RNA molecules that ...
    • Small extracellular vesicles in pre-therapy plasma predict clinical outcome in non-small-cell lung cancer patients 

      Vetsika E.-K., Sharma P., Samaras I., Markou A., Georgoulias V., Whiteside T.L., Kotsakis A. (2021)
      The potential use of plasma-derived small extracellular vesicles (sEV) as predictors of response to therapy and clinical outcome in chemotherapy-naïve patients with non-small-cell lung cancer (NSCLC) was explored. sEV were ...
    • Somatic evolution and global expansion of an ancient transmissible cancer lineage 

      Baez-Ortega A., Gori K., Strakova A., Allen J.L., Allum K.M., Bansse-Issa L., Bhutia T.N., Bisson J.L., Briceño C., Domracheva A.C., Corrigan A.M., Cran H.R., Crawford J.T., Davis E., De Castro K.F., De Nardi A.B., De Vos A.P., Keenan L.D., Donelan E.M., Espinoza Huerta A.R., Faramade I.A., Fazil M., Fotopoulou E., Fruean S.N., Gallardo-Arrieta F., Glebova O., Gouletsou P.G., Häfelin Manrique R.F., Henriques J.J.G.P., Horta R.S., Ignatenko N., Kane Y., King C., Koenig D., Krupa A., Kruzeniski S.J., Kwon Y.-M., Lanza-Perea M., Lazyan M., Lopez Quintana A.M., Losfelt T., Marino G., Castañeda S.M., Martínez-López M.F., Meyer M., Migneco E.J., Nakanwagi B., Neal K.B., Neunzig W., Leathlobhair M.N., Nixon S.J., Ortega-Pacheco A., Pedraza-Ordoñez F., Peleteiro M.C., Polak K., Pye R.J., Reece J.F., Gutierrez J.R., Sadia H., Schmeling S.K., Shamanova O., Sherlock A.G., Stammnitz M., Steenland-Smit A.E., Svitich A., Tapia Martínez L.J., Ngoka I.T., Torres C.G., Tudor E.M., Van Der Wel M.G., Viţălaru B.A., Vural S.A., Walkinton O., Wang J., Wehrle-Martinez A.S., Widdowson S.A.E., Stratton M.R., Alexandrov L.B., Martincorena I., Murchison E.P. (2019)
      The canine transmissible venereal tumor (CTVT) is a cancer lineage that arose several millennia ago and survives by “metastasizing” between hosts through cell transfer. The somatic mutations in this cancer record its ...
    • A ‘waste product’ to save the day in the field of transplantation: The evolving potential of extracellular vesicles 

      Lazana I., Vassilopoulos G. (2022)
      Graft rejection and graft-versus-host disease constitute the leading causes of morbidity and early mortality after solid organ and haematopoietic stem cell transplantation, respectively. Despite the current advances in ...