Πλοήγηση ανά Θέμα "drug dose reduction"
Αποτελέσματα 1-20 από 22
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Ascites in a patient with episodic angio-oedema and eosinophilia: Thinking outside the box
(2017)Episodic angio-oedema with eosinophilia (EAE) or Gleich's syndrome is a rare condition characterised by recurrent episodes of oedema and eosinophilia, accompanied by urticaria, fever and weight gain. The presence of ascites ... -
Autoimmune hepatitis in patients with multiple sclerosis: The role of immunomodulatory treatment
(2019)Background: Development of autoimmune hepatitis (AIH) has been sporadically reported in patients with multiple sclerosis (MS) either concurrently or after treatment with immunomodulatory drugs, including interferon-beta ... -
Black holes and high levels of neurofilaments in glial fibrillary acidic protein – astrocytopathy: a case report
(2020)Background and purpose: Glial fibrillary acidic protein (GFAP) is an intracellular protein of the astrocytic cytoskeleton. Recently, autoantibodies to GFAP detected by cell-based assay in cerebrospinal fluid (CSF) or serum ... -
A case of membranous nephropathy associated with Sjögren syndrome, polymyositis and autoimmune hepatitis
(2008)Sjögren syndrome (SS) is a chronic systemic autoimmune disease characterized by lymphocytic infiltration of exocrine glands, especially lacrimal and salivary. The immunologic process which occurs in this syndrome is B cell ... -
A case report of mesalazine-induced lung injury: A reversible drug side effect
(2019)Introduction: Mesalazine is widely used in the treatment of the acute and maintenance phase of ulcerative colitis (UC). The possibility of interstitial lung disease being induced by mesalazine in the form of eosinophilic ... -
Concurrent cardiac sarcoidosis and obstructive sleep apnea presenting as arrhythmias
(2020)Background: Cardiac involvement is a rare and potentially fatal presentation of sarcoidosis. Obstructive sleep apnea may complicate sarcoidosis. Case presentation: We report a case of a sarcoidosis patient with cardiac ... -
Early primary biliary cirrhosis: A new association with erythema nodosum of unknown origin
(2010)Primary biliary cirrhosis (PBC) is associated with immune-mediated dermatologic disorders. The association of PBC with erythema nodosum (EN) seems rare. We report two females (42 and 44 years old) with low-grade fever, ... -
The effect of 5-azacytidine treatment delays and dose reductions on the prognosis of patients with myelodysplastic syndrome: how to optimize treatment results and outcomes
(2021)The regimen of 5-azacytidine for patients with myelodysplastic syndrome (MDS) has remained unchanged since its first approval. Although several modifications have since been made and delays and dose reductions are common ... -
Efficacy and safety of nintedanib in a greek multicentre idiopathic pulmonary fibrosis registry: A retrospective, observational, cohort study
(2020)Nintedanib is a tyrosine kinase inhibitor approved for the treatment of idiopathic pulmonary fibrosis (IPF). In a retrospective, real-world study across seven Greek hospitals, we evaluated the effectiveness and safety of ... -
FIP1L1-PDGFRA molecular analysis in the differential diagnosis of eosinophilia
(2009)Background: Primary eosinophlia associated with the FIP1L1-PDGFRA rearrangement represents a subset of chronic eosinophilic leukaemia (CEL) and affected patients are very sensitive to imatinib treatment. This study was ... -
Glioblastoma Multiforme in a Patient with Celiac Disease: Management of Seizures After Gross Total Tumor Resection
(2018)Background: A 55-year-old woman with a history of celiac disease presented with focal seizures and a mass lesion located at the left frontal lobe. Management of seizures in these patients is challenging. Case Description: ... -
The IL-1 inhibitor Canakinumab for Familial Mediterranean Fever: The Greek experience in 12 patients
(2015)[No abstract available] -
The influence of β-blockade on the hemodynamic effects of levosimendan in elderly (≥=70 years) patients with acutely decompensated systolic heart failure
(2009)The purpose of this study was to evaluate the influence of chronic β-blockade on the hemodynamic parameters in elderly (≥70 years) patients with acutely decompensated systolic heart failure treated with levosimendan. ... -
Interstitial lung disease in anti-synthetase syndrome
(2019)Anti-synthetase syndrome is an autoimmune disorder characterized by the presence of autoantibodies against aminoacyl transfer RNA (tRNA) synthetases, and myositis, interstitial lung disease (ILD), arthritis, fever and ... -
Mycophenolate for the treatment of autoimmune hepatitis: Prospective assessment of its efficacy and safety for induction and maintenance of remission in a large cohort of treatment-naïve patients
(2011)Background & Aims: Standard therapy for autoimmune hepatitis (AIH) is corticosteroids with or without azathioprine. However, 20% of patients do not respond or are intolerant to conventional treatment. Therefore, we evaluated ... -
Outcomes in meningitis/ventriculitis treated with intravenous or intraventricular plus intravenous colistin
(2016)Background: The aim of this work is to evaluate the outcome of patients treated with intrathecal colistin for meningitis/ventriculitis. Methods: This retrospective case series study included patients presenting with ... -
A real-world study focused on the long-term efficacy of mycophenolate mofetil as first-line treatment of autoimmune hepatitis
(2016)Background Front-line therapy with mycophenolate mofetil (MMF) in autoimmune hepatitis (AIH) has shown high on-treatment remission rates. Aim To study prospectively in a real-world fashion the long-term outcome of a large ... -
Real-world treatment patterns, patient-reported outcomes, and effectiveness of flexible-dosing etanercept in patients with plaque psoriasis in Greece
(2022)Etanercept is approved for continuous or intermittent use and flexible dosing in plaque psoriasis (PsO). The objectives of this study were to investigate real-world treatment patterns with etanercept in Greek adults with ... -
A single load of fructose attenuates the risk of exercise-induced hypoglycemia in adults with type 1 diabetes on ultra-long-acting basal insulin: A randomized, open-label, crossover proof-of-principle study
(2020)OBJECTIVE While the adjustment of insulin is an established strategy to reduce the risk of exercise-associated hypoglycemia for individuals with type 1 diabetes, it is not easily feasible for those treated with ultra-long-acting ...