Πλοήγηση ανά Θέμα "computer simulation"
Αποτελέσματα 1-20 από 56
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Application of a One-Dimensional Computational Model for the Prediction of Deposition from a Dry Powder Inhaler
(2017)Background: Accurate prediction of the regional deposition of inhaled dry powders as a function of powder properties and breathing pattern is a long-term research goal for pulmonary drug delivery. In the present work, ... -
Assessing the results of a virtual pressure management project applied in Kos Town water distribution network
(2016)Water pressure management (PM) is one of the most cost-effective ways for a water utility to reduce water leakage, pipes’ bursts, improve the level of services provided to its customers and lower its operating expenses. ... -
Bar-HRM for Species Confirmation of Native Plants Used in Forest Restoration in Northern Thailand
(2022)Plant species confirmation is a crucial step in using native plant species for forest restoration. To enhance this, a hybrid method of DNA barcoding and high-resolution melting analysis (Bar-HRM) was investigated in this ... -
Blood flow and diameter effect in the navigation process of magnetic nanocarriers inside the carotid artery
(2022)Background and objective: Serious side effects are occurred during the cancer therapy. Magnetic driving of nanoparticles is a novel method for the elimination of these effects by supplying with anticancer drug or increase ... -
Bootstrap-based testing approaches for the assessment of the diagnostic accuracy of biomarkers subject to a limit of detection
(2019)Assessment of the diagnostic accuracy of biomarkers through receiver operating characteristic curve analysis frequently involves a limit of detection imposed by the laboratory analytical system precision. As a consequence, ... -
Calculation of multiple critical depths in open channels using an adaptive cubic polynomials algorithm
(2020)A method for the calculation of multiple critical depths in compound and natural channels, using an adaptive cubic polynomials algorithm (ACPA), is presented in this paper. The algorithm is based on the approximation of ... -
Carotid Bifurcation Geometry and Atherosclerosis
(2017)Hemodynamic changes occurring at the initial segments of the arterial bifurcations appear to play an important role in the development of atherosclerotic plaque. Therefore, arterial geometry might be a potential marker for ... -
Cheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL)
(2017)We present an in silico drug discovery pipeline developed and applied for the identification and virtual screening of small-molecule Protein-Protein Interaction (PPI) compounds that act as dual inhibitors of TNF and RANKL ... -
A computational fluid dynamics modelling of maternal-fetal heat exchange and blood flow in the umbilical cord
(2020)Human fetal thermoregulation, maternal-fetal heat exchange, and the role of the umbilical cord in these processes are not well understood. Ethical and technical limitations have restricted current knowledge to animal ... -
A computer algebra system approach in gene expression analysis
(2017)The primary purpose of this study is to provide an immediate connection to analytics of biological functions and visualisation. We introduce a visual framework in the environment of a main computer algebra system (CAS), ... -
Computer-simulation-based selection of optimal monomer for imprinting of tri-O-acetyl adenosine in a polymer matrix: calculations for benzene solution
(2016)Molecular imprinting is a promising way to create polymer materials that can be used as artificial receptors, and have anticipated use in synthetic imitation of natural antibodies. In case of successful imprinting, the ... -
Confidence intervals for differences between volumes under receiver operating characteristic surfaces (VUS) and generalized Youden indices (GYIs)
(2018)This article explores both existing and new methods for the construction of confidence intervals for differences of indices of diagnostic accuracy of competing pairs of biomarkers in three-class classification problems and ... -
Construction of joint confidence regions for the optimal true class fractions of Receiver Operating Characteristic (ROC) surfaces and manifolds
(2017)The three-class approach is used for progressive disorders when clinicians and researchers want to diagnose or classify subjects as members of one of three ordered categories based on a continuous diagnostic marker. The ... -
Coupled FEA Model with Continuum Damage Mechanics for the Degradation of Polymer-based coatings on Drug-Eluting Stents
(2021)Drug-Eluting Stents (DES) are commonly used in Coronary angioplasty procedures to reduce the phenomenon of restenosis. Numerical simulations are proven to be a useful tool to the Bioengineering community in computing the ... -
Coupled numerical simulation of low-cycle fatigue damage in metal components
(2021)A coupled cyclic plasticity-damage model is implemented for simulating low-cycle fatigue in metal components. Constitutive relations account for J2-flow theory with nonlinear kinematic/isotropic hardening, coupled with ... -
A data-driven hypothesis on the epigenetic dysregulation of host metabolism by SARS coronaviral infection: Potential implications for the SARS-CoV-2 modus operandi
(2020)COVID-19, the disease caused by the novel SARS-CoV-2, a betacoronavirus structurally similar to SARS-CoV. Based on both structural and syndromic similarities with SARS-CoV, a hypothesis is formed on SARS-CoV-2 potential ... -
Demographic window to aging in the wild: Constructing life tables and estimating survival functions from marked individuals of unknown age
(2004)We address the problem of establishing a survival schedule for wild populations. A demographic key identity is established, leading to a method whereby age-specific survival and mortality can be deduced from a marked cohort ... -
Discovery and characterization of 2-anilino-4- (thiazol-5-yl)pyrimidine transcriptional CDK inhibitors as anticancer agents
(2010)The main difficulty in the development of ATP antagonist kinase inhibitors is target specificity, since the ATP-binding motif is present in many proteins. We introduce a strategy that has allowed us to identify compounds ... -
Double hit viral parasitism, polymicrobial CNS residency and perturbed proteostasis in Alzheimer's disease: A data driven, in silico analysis of gene expression data
(2020)The aim of this study was to determine the interaction of peripheral immunity vs. the CNS in the setting of AD pathogenesis at the transcriptomic level in a data driven manner. For this purpose, publicly available gene ... -
Environmental parameters as risk factors for human and canine Leishmania infection in Thessaly, Central Greece
(2016)Thessaly, Central Greece, is an endemic area for leishmaniasis with higher incidence rate during the last years. We herein investigated the geographical distribution of human leishmaniasis cases and Leishmania infected ...