Πλοήγηση ανά Θέμα "cancer prognosis"

99mTc sestamibi as a prognostic factor of response to first-line therapy and outcome in patients with malignant lymphoma

Spyridonidis, T. J.; Matsouka, P.; Symeonidis, A.; Savvopoulos, C.; Vassilakos, P. J.; Apostolopoulos, D. J. (2013)

INTRODUCTION: Resistance to chemotherapy poses a major problem in cancer patients. Although of multifactorial origin, some of the implicated mechanisms also interfere with Tc-MIBI uptake and retention in cancer cells. The ...

Adherence to Mediterranean Diet and Nutritional Status in Women with Breast Cancer: What Is Their Impact on Disease Progression and Recurrence-Free Patients’ Survival?

Mantzorou M., Tolia M., Poultsidi A., Vasios G.K., Papandreou D., Theocharis S., Kavantzas N., Troumbis A.Y., Giaginis C. (2022)

Introduction: Nutritional status impacts the survival of patients with cancer. There are few studies that investigate the role of nutritional status on breast cancer survival in women with breast cancer, and even fewer ...

AJCC-8 TNM Staging System for Gastric Cancer. Is There a Scope for Improvement?: (Invited brief commentary on a paper entitled: Proposed modification of the 8th edition of the AJCC staging system for gastric cancer)

Tsoukalas N., Tsapakidis K., Kamposioras K. (2020)

[No abstract available]

aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis

Fan R., Papatheodoridis G., Sun J., Innes H., Toyoda H., Xie Q., Mo S., Sypsa V., Guha I.N., Kumada T., Niu J., Dalekos G., Yasuda S., Barnes E., Lian J., Suri V., Idilman R., Barclay S.T., Dou X., Berg T., Hayes P.C., Flaherty J.F., Zhou Y., Zhang Z., Buti M., Hutchinson S.J., Guo Y., Calleja J.L., Lin L., Zhao L., Chen Y., Janssen H.L.A., Zhu C., Shi L., Tang X., Gaggar A., Wei L., Jia J., Irving W.L., Johnson P.J., Lampertico P., Hou J. (2020)

Background & Aims: Hepatocellular carcinoma (HCC) is the leading cause of death in patients with chronic hepatitis. In this international collaboration, we sought to develop a global universal HCC risk score to predict the ...

Anti-Ro52 antibody is highly prevalent and a marker of better prognosis in patients with ovarian cancer

Bogdanos D.P., Gkoutzourelas A., Papadopoulos V., Liaskos C., Patrikiou E., Tsigalou C., Saratziotis A., Hajiioannou J., Scheper T., Meyer W., Sakkas L.I., Papandreou C. (2021)

Background and Aims: Anti-Ro52 antibody (Ab) reactivity is highly prevalent in autoimmune rheumatic diseases (ARDs), mainly Sjögren's syndrome (SjS) and systemic lupus erythematosus (SLE), but also in other inflammatory ...

Application of Radiomics and Decision Support Systems for Breast MR Differential Diagnosis

Tsougos I., Vamvakas A., Kappas C., Fezoulidis I., Vassiou K. (2018)

Over the years, MR systems have evolved from imaging modalities to advanced computational systems producing a variety of numerical parameters that can be used for the noninvasive preoperative assessment of breast pathology. ...

Benign intracranial lesions-radiotherapy: An overview of treatment options, indications and therapeutic results

Tzikoulis V., Gkantaifi A., Alongi F., Tsoukalas N., Saraireh H.H., Charalampakis N., Tzikoulis G., Andreou E., Tsapakidis K., Kardamakis D., Tsanadis K., Kyrgias G., Tolia M. (2020)

Background: Radiation Therapy (RT) is an established treatment option for benign intracranial lesions. The aim of this study is to display an update on the role of RT concerning the most frequent benign brain lesions and ...

Biomarkers in prostate-specific membrane antigen theranostics

Vlachostergios P.J., Zachos I., Tzortzis V. (2021)

Theranostics of prostate cancer (PC) represents a growing area of development of imaging agents and targeted radionuclide therapeutics against a major target, prostate specific membrane antigen (PSMA). In view of the ...

Can bioelectrical impedance analysis and BMI be a prognostic tool in head and neck cancer patients? A review of the evidence

Mantzorou M., Tolia M., Poultsidi A., Pavlidou E., Papadopoulou S.K., Papandreou D., Giaginis C. (2020)

Background: Malnutrition can significantly affect disease progression and patient survival. The efficiency of weight loss and bioimpedance analysis (BIA)-derived measures in the evaluation of malnutrition, and disease ...

CD90/Thy-1, a cancer-associated cell surface signaling molecule

Sauzay C., Voutetakis K., Chatziioannou A.A., Chevet E., Avril T. (2019)

CD90 is a membrane GPI-anchored protein with one Ig V-type superfamily domain that was initially described in mouse T cells. Besides the specific expression pattern and functions of CD90 that were described in normal tissues ...

Circulating tumor cells as prognostic biomarkers in breast cancer: current status and future prospects

Chantzara E., Xenidis N., Kallergi G., Georgoulias V., Kotsakis A. (2021)

Introduction : Despite advances in diagnostic and therapeutic techniques breast cancer is still associated with significant morbidity and mortality. CTCs play a crucial role in the metastatic process, which is the main ...

Clinical Significance of Circulating Osteopontin Levels in Patients With Lung Cancer and Correlation With VEGF and MMP-9

Kerenidi T., Kazakou A.P., Lada M., Tsilioni I., Daniil Z., Gourgoulianis K.I. (2016)

Osteopontin (OPN) is a multifunctional cytokine involved in carcinogenesis. Serum levels of OPN, vascular endothelial growth factor (VEGF), and matrix metalloproteinase-9 (MMP-9) were measured by ELISA in 90 lung cancer ...

COVID-19 and human reproduction: A pandemic that packs a serious punch

Anifandis G., Tempest H.G., Oliva R., Swanson G.M., Simopoulou M., Easley C.A., Primig M., Messini C.I., Turek P.J., Sutovsky P., Ory S.J., Krawetz S.A. (2021)

The COVID-19 pandemic has led to a worldwide health emergency that has impacted 188 countries at last count. The rapid community transmission and relatively high mortality rates with COVID-19 in modern times are relatively ...

The effect of 5-azacytidine treatment delays and dose reductions on the prognosis of patients with myelodysplastic syndrome: how to optimize treatment results and outcomes

Diamantopoulos P.T., Symeonidis A., Pappa V., Kotsianidis I., Galanopoulos A., Pontikoglou C., Anagnostopoulos A., Vassilopoulos G., Zikos P., Hatzimichael E., Papaioannou M., Megalakaki A., Repousis P., Kotsopoulou M., Dimou M., Solomou E., Dryllis G., Tsokanas D., Papoutselis M.-K., Papageorgiou S., Kyrtshonis M.-C., Kourakli A., Papadaki H., Panayiotidis P., Viniou N.-A. (2021)

The regimen of 5-azacytidine for patients with myelodysplastic syndrome (MDS) has remained unchanged since its first approval. Although several modifications have since been made and delays and dose reductions are common ...

Effects of TP53 and PIK3CA mutations in early breast cancer: a matter of co-mutation and tumor-infiltrating lymphocytes

Kotoula V., Karavasilis V., Zagouri F., Kouvatseas G., Giannoulatou E., Gogas H., Lakis S., Pentheroudakis G., Bobos M., Papadopoulou K., Tsolaki E., Pectasides D., Lazaridis G., Koutras A., Aravantinos G., Christodoulou C., Papakostas P., Markopoulos C., Zografos G., Papandreou C., Fountzilas G. (2016)

The purpose of this study is to investigate whether the outcome of breast cancer (BC) patients treated with adjuvant chemotherapy is affected by co-mutated TP53 and PIK3CA according to stromal tumor-infiltrating lymphocytes ...

Endocan and the respiratory system: A review

Kechagia M., Papassotiriou I., Gourgoulianis K.I. (2016)

Endocan, formerly called endothelial cell-specific molecule 1, is an endothelial cell-associated proteoglycan that is preferentially expressed by renal and pulmonary endothelium. It is upregulated by proangiogenic molecules ...

Endothelin-1 indicates unfavorable prognosis in primary high-grade non-muscle-invasive urothelial bladder cancer

Mitrakas L., Gravas S., Karasavvidou F., Zachos I., Karatzas A., Oeconomou A., Koukoulis G., Tzortzis V., Papandreou C., Mitrakas L. (2021)

Objective: To conduct a prospective study of the potential prognostic role of endothelin-1 (ET-1) in a cohort of primary high-grade non-muscle-invasive urothelial bladder cancer patients, who were treated with adjuvant ...

ERK signaling controls productive HIF-1 binding to chromatin and cancer cell adaptation to hypoxia through HIF-1α interaction with NPM1

Koukoulas K., Giakountis A., Karagiota A., Samiotaki M., Panayotou G., Simos G., Mylonis I. (2021)

The hypoxia-inducible factor HIF-1 is essential for oxygen homeostasis. Despite its well-understood oxygen-dependent expression, regulation of its transcriptional activity remains unclear. We show that phosphorylation by ...

ETV6/RUNX1-positive childhood acute lymphoblastic leukemia (ALL): The spectrum of clonal heterogeneity and its impact on prognosis

Ampatzidou Μ., Papadhimitriou S.I., Paterakis G., Pavlidis D., Tsitsikas Κ., Kostopoulos I.V., Papadakis V., Vassilopoulos G., Polychronopoulou S. (2018)

The prognostic significance of the ETV6/RUNX1-fusion and of the accompanying aberrations is disputable; whether co-existing sub-clones are responsible for delayed MRD-clearance and thus, moderate outcome, remains to be ...

Exploring the potential of mucin 13 (MUC13) as a biomarker for carcinomas and other diseases

Filippou P.S., Ren A.H., Korbakis D., Dimitrakopoulos L., Soosaipillai A., Barak V., Frenkel S., Pe'Er J., Lotem M., Merims S., Molina R., Blasutig I., Bogdanos D.P., Diamandis E.P. (2018)

Mucin 13 (MUC13) is a cell surface glycoprotein aberrantly expressed in a variety of epithelial carcinomas. Thus far, the role of MUC13 in various diseases remains elusive. To the best of our knowledge, this is the first ...